Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Longhuan Ma"'
Autor:
Longhuan Ma, Morgan Terrell, Josephine Brown, Abigail Castellanos Garcia, Ahmed Elshikha, Laurence Morel
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundMounting evidence suggests that increased gut permeability, or leaky gut, and the resulting translocation of pathobionts or their metabolites contributes to the pathogenesis of Systemic Lupus Erythematosus. However, the mechanisms underlyin
Externí odkaz:
https://doaj.org/article/3913bd83cc71405b952edc18163d01b1
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 6, Pp 1561-1566 (2021)
Recent reemergence of pertussis (whooping cough) in highly vaccinated populations and rapid expansion of Bordetella pertussis strains lacking pertactin (PRN), a common acellular vaccine antigen, have raised the specter of vaccine-driven evolution and
Externí odkaz:
https://doaj.org/article/41b616159b1643b4a930bd07532b23c8
Autor:
Longhuan Ma, Laurence Morel
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Systemic Lupus Erythematosus is a complex autoimmune disease and its etiology remains unknown. Increased gut permeability has been reported in lupus patients, yet whether it promotes or results from lupus progression is unclear. Recent studies indica
Externí odkaz:
https://doaj.org/article/56bf02083b1e4c1791663ecc9d736f8e
Autor:
Illiassou H. Soumana, Kalyan K. Dewan, Bodo Linz, Israel Rivera, Longhuan Ma, Laura K. Howard, Amanda D. Caulfield, Colleen J. Sedney, Uriel Blas-Machado, Peter Sebo, Eric T. Harvill
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 5 (2022)
Pertussis (whooping cough) is a highly transmissible human respiratory disease caused by Bordetella pertussis, a human-restricted pathogen. Animal models generally involve pneumonic infections induced by depositing large numbers of bacteria in the lu
Externí odkaz:
https://doaj.org/article/4809b2a2ddca4bc081a6a4f564867de7
Autor:
Josephine Brown, Georges Abboud, Longhuan Ma, Seung-Chul Choi, Nathalie Kanda, Leilani Zeumer-Spataro, Jean Lee, Weidan Peng, Joy Cagmat, Tamas Faludi, Mansour Mohamadzadeh, Timothy Garrett, Laura Mandik-Nayak, Alexander Chervonsky, Andras Perl, Laurence Morel
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104241- (2022)
Summary: A skewed tryptophan metabolism has been reported in patients with lupus. Here, we investigated the mechanisms by which it occurs in lupus-susceptible mice, and how tryptophan metabolites exacerbate T cell activation. Metabolomic analyses dem
Externí odkaz:
https://doaj.org/article/d23480af288b4f76bbaf7d930d6da554
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Chronic otitis media (COM) is the long-term infection and inflammation of the middle ears typically caused by upper respiratory tract pathogens that are able to ascend the Eustachian tube. Our understanding of contributing factors is limited because
Externí odkaz:
https://doaj.org/article/2472a08460644a9aaae48326e50c58bc
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
A variety of bacteria have evolved the ability to interact with environmental phagocytic predators such as amoebae, which may have facilitated their subsequent interactions with phagocytes in animal hosts. Our recent study found that the animal patho
Externí odkaz:
https://doaj.org/article/f3191690690246adbd9483f41669bd85
Autor:
Kalyan K. Dewan, Colleen Sedney, Amanda D. Caulfield, Yang Su, Longhuan Ma, Uriel Blas-Machado, Eric T. Harvill
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2022)
Acute otitis media (AOM) is commonly caused by bacterial pathobionts of the nasopharynx that ascend the Eustachian tube to cause disease in the middle ears. To model and study the various complexities of AOM, common human otopathogens are injected di
Externí odkaz:
https://doaj.org/article/5e0b76720b444706ab5dcd9926c284ad
Autor:
Longhuan Ma, Kalyan K. Dewan, Dawn L. Taylor-Mulneix, Shannon M. Wagner, Bodo Linz, Israel Rivera, Yang Su, Amanda D. Caulfield, Uriel Blas-Machado, Eric T. Harvill
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8 (2021)
Whooping cough is resurging in the United States despite high vaccine coverage. The rapid rise of Bordetella pertussis isolates lacking pertactin (PRN), a key vaccine antigen, has led to concerns about vaccine-driven evolution. Previous studies showe
Externí odkaz:
https://doaj.org/article/060a2183d6cc4a8189e3a87d0ecf070c
Autor:
Israel Rivera, Bodo Linz, Kalyan K. Dewan, Longhuan Ma, Christopher A. Rice, Dennis E. Kyle, Eric T. Harvill
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Animal and human pathogens of the genus Bordetella are not commonly considered to be intracellular pathogens, although members of the closely related classical bordetellae are known to enter and persist within macrophages in vitro and have anecdotall
Externí odkaz:
https://doaj.org/article/1835c151f5a344f1925ae8de0da66139