Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Longhua Liu"'
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Obesity significantly contributes to the progression of cardiovascular diseases (CVDs) and elevates the risk of cardiovascular mortality. Atherosclerosis, the primary pathogenic process underlying CVDs, initiates with vascular endothelial dysfunction
Externí odkaz:
https://doaj.org/article/a53078a05a3e4daa85ef8015f32883a6
Autor:
Lihui Wang, Yinghao Li, Renfeng Li, Jinwen Luan, Kaiming Cao, Tiancheng Liu, Haiyang Hu, Shanshan Chen, Le Bu, Longhua Liu, Hongzhi Wang, Qing Lu
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
Pancreatic fat is associated with obesity and type 2 diabetes mellitus (T2DM); however, the relationship between different types of pancreatic fat and diabetes status remains unclear. Therefore, we aimed to determine the potential of different types
Externí odkaz:
https://doaj.org/article/9a3a3e7461aa48d898f6f418dbee645f
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Atherosclerosis is the hallmark of cardiovascular disease (CVD) which is a leading cause of death in type 2 diabetes patients, and glycemic control is not beneficial in reducing the potential risk of CVD. Clinically, it was shown that Thiazolidinedio
Externí odkaz:
https://doaj.org/article/153896699bba4f75a529c603ad3a0ce5
Publikováno v:
Biomolecules, Vol 12, Iss 12, p 1832 (2022)
The number of patients with type 2 diabetes mellitus (T2DM), which is mainly characterized by insulin resistance and insulin secretion deficiency, has been soaring in recent years. Accompanied by many other metabolic syndromes, such as cardiovascular
Externí odkaz:
https://doaj.org/article/8437a760ab8c487bb124d97839618439
Autor:
Nicole Aaron, Michael J Kraakman, Qiuzhong Zhou, Qiongming Liu, Samantha Costa, Jing Yang, Longhua Liu, Lexiang Yu, Liheng Wang, Ying He, Lihong Fan, Hiroyuki Hirakawa, Lei Ding, James Lo, Weidong Wang, Baohong Zhao, Edward Guo, Lei Sun, Cliff J Rosen, Li Qiang
Publikováno v:
eLife, Vol 10 (2021)
Background: Marrow adipose tissue (MAT) has been shown to be vital for regulating metabolism and maintaining skeletal homeostasis in the bone marrow (BM) niche. As a reflection of BM remodeling, MAT is highly responsive to nutrient fluctuations, horm
Externí odkaz:
https://doaj.org/article/dafb113ceb224ac9aedae25c7e925dc7
Autor:
Tarik Zahr, Longhua Liu, Michelle Chan, Qiuzhong Zhou, Bishuang Cai, Ying He, Nicole Aaron, Domenico Accili, Lei Sun, Li Qiang
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 43:30-44
Background: Atherosclerosis is a medical urgency manifesting at the onset of hypercholesterolemia and is associated with aging. Activation of PPARγ (peroxisome proliferator-activated receptor γ) counteracts metabolic dysfunction influenced by aging
Exercise Promotes Bone Marrow Microenvironment by Inhibiting Adipsin in Diet-Induced Male Obese Mice
Autor:
Zunhan Shi, Lihui Wang, Jinwen Luan, Liqin Yin, Xiaohui Ji, Wenqian Zhang, Bingxiang Xu, Linshan Chen, Ying He, Ru Wang, Longhua Liu
Publikováno v:
Nutrients; Volume 15; Issue 1; Pages: 19
Obesity is a growing global epidemic linked to many diseases, including diabetes, cardiovascular diseases, and musculoskeletal disorders. Exercise can improve bone density and decrease excess bone marrow adipose tissue (BMAT) in obese individuals. Ho
Autor:
Ying He, Alana B'nai Taub, Lexiang Yu, Yifan Yao, Ruotong Zhang, Tarik Zahr, Nicole Aaron, Joseph LeSauter, Lihong Fan, Longhua Liu, Ruya Tazebay, Jianwen Que, Utpal Pajvani, Liheng Wang, Rae Silver, Li Qiang
Publikováno v:
Advanced science (Weinheim, Baden-Wurttemberg, Germany).
Systemic glucose metabolism and insulin activity oscillate in response to diurnal rhythms and nutrient availability with the necessary involvement of adipose tissue to maintain metabolic homeostasis. However, the adipose-intrinsic regulatory mechanis
Publikováno v:
Am J Physiol Endocrinol Metab
Obesity is a potent risk factor for atherosclerotic morbidity and mortality. Cytokines secreted from adipose tissue, namely, adipokines, have been suggested to be actively involved in atherosclerosis. One of the most abundant adipokines, adipsin, is
Publikováno v:
Cellular and Molecular Life Sciences. 79
Characterized by a surplus of whole-body adiposity, obesity is strongly associated with the prognosis of atherosclerosis, a hallmark of coronary artery disease (CAD) and the major contributor to cardiovascular disease (CVD) mortality. Adipose tissue