Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Longchuan Yu"'
Publikováno v:
Brain Sciences, Vol 13, Iss 4, p 590 (2023)
Studies have demonstrated that the α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor is essential to drug addiction. In this study, we explored the influence of GluR2-3Y, an interfering peptide to prevent the endocytosis of AMPA r
Externí odkaz:
https://doaj.org/article/a291f2c7ac0f4b7a940fecf0a24e853c
Publikováno v:
Brain Sciences, Vol 12, Iss 8, p 985 (2022)
Drugs of abuse cause enduring functional disorders in the brain reward circuits, leading to cravings and compulsive behavior. Although people may rehabilitate by detoxification, there is a high risk of relapse. Therefore, it is crucial to illuminate
Externí odkaz:
https://doaj.org/article/8cf995866607443491e0c2938c3e1803
Autor:
Yusheng Qu, Robert Kirby, Richard Davies, Ayesha Jinat, Stefano Stabilini, Bin Wu, Longchuan Yu, BaoXi Gao, Hugo M. Vargas
Publikováno v:
Nucleic Acid Therapeutics. 33:132-140
Autor:
Yusheng, Qu, Robert, Kirby, Richard, Davies, Ayesha, Jinat, Stefano, Stabilini, Bin, Wu, Longchuan, Yu, BaoXi, Gao, Hugo M, Vargas
Publikováno v:
Nucleic acid therapeutics.
In accord with International Conference on Harmonization S7B guidelines, an
Autor:
William G. Richards, Denise Dwyer, Michael S. Ominsky, Kelly S. Villasenor, Qing-Tian Niu, Xiaodong Li, Marina Stolina, Mario Grisanti, Shawn T. Alexander, Frank Asuncion, James E. Tomlinson, Kelly Hensley, Hua Zhu Ke, Longchuan Yu, Chun-Ya Han, Charles W. Dean
Publikováno v:
Bone. 105:163-172
Sustained elevation of parathyroid hormone (PTH) is catabolic to cortical bone, as evidenced by deterioration in bone structure (cortical porosity), and is a major factor for increased fracture risk in chronic kidney disease (CKD). Etelcalcetide (AMG
Autor:
Chun-Ya Han, Xiaodong Li, William G. Richards, Shawn T. Alexander, James E. Tomlinson, Longchuan Yu, Charles W. Dean, Denise Dwyer, William G. Goodman, Marina Stolina, Kelly Hensley
Publikováno v:
Calcified Tissue International
Etelcalcetide, a novel peptide agonist of the calcium-sensing receptor, prevents vascular calcification in a rat model of renal insufficiency with secondary hyperparathyroidism. Vascular calcification occurs frequently in patients with chronic kidney
Autor:
William G. Richards, Ji Li, Frank Asuncion, Shirley Steavenson, Qing-Tian Niu, Kristi Daris, Tom Horan, Barbara Tipton, Mario Grisanti, Edward Lee, Mark Daris, Eliane G. Valente, Philip Babij, Hong-Lin Tan, Wei Fan, Chun-Ya Han, Hossein Salimi-Moosavi, Denise Dwyer, Paul J. Kostenuik, Zhaopo Geng, Mauricio Barrero, Hsieng Sen Lu, David L. Lacey, Marina Stolina, W. Scott Simonet, Frederick W. Jacobsen, Jackie Sheng, Rohini Deshpande, Pam Kurimoto, Aaron George Winters, Chaoyang Li, Xiaodong Li, Min Liu, Michael S. Ominsky, Longchuan Yu, Jae Lee, Hua Zhu Ke, Raj Haldankar, Qing Chen, Jennifer Lavallee
Publikováno v:
Journal of Bone and Mineral Research. 26:2610-2621
The physiological role of Dickkopf-1 (Dkk1) during postnatal bone growth in rodents and in adult rodents was examined utilizing an antibody to Dkk1 (Dkk1-Ab) that blocked Dkk1 binding to both low density lipoprotein receptor-related protein 6 (LRP6)
Autor:
Violeta Yu, David J. St. Jean, Youping Wang, Yen Nguyen, Longchuan Yu, David Powers, Chun-Ya E. Han, Xiaoling Xiong, Philip Babij
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:1442-1445
A chemical screen of 45,000 compounds from a diverse collection led to the identification of two series of small molecules with potent osteogenic activity in mouse MC3T3-E1 osteoblast cells. The first chemical group was characterized by an amino benz
Publikováno v:
Journal of Biological Chemistry. 269:30777-30780
A glycoprotein of M(r) 160,000 (gp160) represents the major protein component of GLUT4-containing vesicles other than GLUT4 itself. These vesicles are the tissue-specific secretory-like microsomal structures that are responsible for insulin-dependent
Autor:
Tom Graves, Michael Bass, Mark Chhoa, Sean Morony, George A. Carlson, Chi-Ming Li, Julie Amato, William G. Richards, Christine Ebeling, Chun-Ya E. Han, Longchuan Yu, Mario Grisanti, Todd Juan, Martine Roudier, David Lloyd, Philip Babij, Xiaodong Li, Denise Dwyer
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 24(9)
A large genome-wide, recessive, N-ethyl-N-nitrosourea (ENU)-induced mutagenesis screen was performed on a mixed C57BL/6J and C3H.SW-H2/SnJ mouse background to identify genes regulating bone mass. Approximately 6500 male and female G(3) hybrid mice we