Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Longchuan Chen"'
Autor:
Hailong Wang, Linda Z Shi, Catherine C L Wong, Xuemei Han, Patty Yi-Hwa Hwang, Lan N Truong, Qingyuan Zhu, Zhengping Shao, David J Chen, Michael W Berns, John R Yates, Longchuan Chen, Xiaohua Wu
Publikováno v:
PLoS Genetics, Vol 9, Iss 2, p e1003277 (2013)
CtIP plays an important role in homologous recombination (HR)-mediated DNA double-stranded break (DSB) repair and interacts with Nbs1 and BRCA1, which are linked to Nijmegen breakage syndrome (NBS) and familial breast cancer, respectively. We identif
Externí odkaz:
https://doaj.org/article/8606f4a68b27439399514e14dd129d54
Autor:
Qiuling Su, Longchuan Chen, Zhigao Huang, Jingying Zhang, Zhiya Lin, Yue Chen, Yanmin Yang, Yingbin Lin, Zhisheng Wang, Wei Chen
Publikováno v:
Journal of Alloys and Compounds. 711:462-472
Layered LiNi 1/3 Co 1/3 Mn 1/3 O 2 cathode materials were prepared using a sol-gel method and subsequently surface-modified with YF 3 layer by a wet chemical process. In comparison with pristine LiNi 1/3 Co 1/3 Mn 1/3 O 2 , LiNi 1/3 Co 1/3 Mn 1/3 O 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10b75648c401d3918fe9b640f6d661f8
https://doi.org/10.1016/j.jallcom.2017.03.130
https://doi.org/10.1016/j.jallcom.2017.03.130
Autor:
Arthur J.L. Cooper, Xiaoming Deng, Neil Hoa, John T. Pinto, Brankica Paunovic, Ganna Tolstanova, Joanna Kolodney, Longchuan Chen, Gordon D. McLaren, Tetyana Khomenko, Boris F. Krasnikov, Sandor Szabo
Publikováno v:
Archives of Biochemistry and Biophysics. 525:60-70
Cysteamine, a coenzyme A metabolite, induces duodenal ulcers in rodents. Our recent studies showed that ulcer formation was aggravated by iron overload and diminished in iron deficiency. We hypothesized that cysteamine is selectively taken up in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65bfb3682ba2e82fc2551590fd8e4220
https://doi.org/10.1016/j.abb.2012.05.013
https://doi.org/10.1016/j.abb.2012.05.013
Autor:
Jiahuai Han, Rong Liao, Naoto Yoshizuka, Guoliang Yu, Zeyu Xu, Wen-Yuan Hu, Lixin Hong, Rebecca M. Chen, Peiqing Sun, Longchuan Chen
Publikováno v:
Molecular and Cellular Biology. 32:606-618
The p38 mitogen-activated protein kinase (MAPK) pathway has been implicated in both suppression and promotion of tumorigenesis. It remains unclear how these 2 opposite functions of p38 operate in vivo to impact cancer development. We previously repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::993b7f31c65f2bb42ec4033533c97209
https://doi.org/10.1128/mcb.06301-11
https://doi.org/10.1128/mcb.06301-11
Autor:
Tetyana Khomenko, Sandor Szabo, Klara Osapay, Judah Folkman, Ximing Xiong, Joseph Shiloach, Zsuzsanna Sandor, Ganna Tolstanova, Xiaoming Deng, Longchuan Chen
Publikováno v:
Dig Dis Sci
BACKGROUND: Despite recent advances and better understanding of the etiology and the pathogenesis of gastrointestinal ulcer diseases, e.g., duodenal ulcer, the molecular events leading to ulcer development, delayed healing, and recurrence remain poor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2ab61295282748d6d5a8a301e37ec72
https://doi.org/10.1007/s10620-011-1753-4
https://doi.org/10.1007/s10620-011-1753-4
Autor:
Maria Dora Carrion, Olga Cruz-Lopez, Giampietro Viola, Roberta Bortolozzi, Longchuan Chen, Pier Giovanni Baraldi, Andrea Brancale, Ernest Hamel, Carlota Lopez Cara, Romeo Romagnoli, Giuseppe Basso
Publikováno v:
Journal of Medicinal Chemistry. 53:4248-4258
A series of 1-aryl-5-(3',4',5'-trimethoxyphenyl) derivatives and their related 1-(3',4',5'-trimethoxyphenyl)-5-aryl-1,2,4-triazoles, designed as cis-restricted combretastatin analogues, were synthesized and evaluated for antiproliferative activity, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02723622fb73d1da6a87e09faa2d73ef
https://doi.org/10.1021/jm100245q
https://doi.org/10.1021/jm100245q
Autor:
Xiaoming Deng, Andrzej S. Tarnawski, Amrita Ahluwalia, Sandor Szabo, Longchuan Chen, Ganna Tolstanova, Tetyana Khomenko, Zsuzsanna Sandor
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 328:749-757
In ulcerative colitis (UC), an increased expression of vascular endothelial growth factor (VEGF) correlates with disease activity, but a causal relationship is unknown. We tested the hypothesis that VEGF plays a mechanistic role in the pathogenesis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c99d9faf270841d8d7d7bda7be9c57a1
https://doi.org/10.1124/jpet.108.145128
https://doi.org/10.1124/jpet.108.145128
Publikováno v:
Journal of Biological Chemistry. 283:7713-7720
BRCA1 plays an important role in the homologous recombination (HR)-mediated DNA double-strand break (DSB) repair, but the mechanism is not clear. Here we describe that BRCA1 forms a complex with CtIP and MRN (Mre11/Rad50/Nbs1) in a cell cycle-depende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75b9041e89ab9b120632e811f03403bf
https://doi.org/10.1074/jbc.m710245200
https://doi.org/10.1074/jbc.m710245200
Autor:
Sandor Szabo, Xiaoming Deng, Martin R. Jadus, Longchuan Chen, Tetyana Khomenko, Masashi Yoshida
Publikováno v:
Digestive Diseases and Sciences. 53:375-384
We assessed the expression of about 8,000 known or unknown genes in the preulcerogenic stages of cysteamine-induced duodenal ulceration in rats, in comparison with the toxic but nonulcerogen ethanolamine. The most prominent gene changes were confirme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f75e5fcb1aec235de048a5448675496a
https://doi.org/10.1007/s10620-007-9890-5
https://doi.org/10.1007/s10620-007-9890-5
Publikováno v:
Journal of Biological Chemistry. 282:22939-22952
The Mre11-Rad50-Nbs1 (MRN) complex is required for mediating the S-phase checkpoint following UV treatment, but the underlying mechanism is not clear. Here we demonstrate that at least two mechanisms are involved in regulating the S-phase checkpoint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::315f0bfea83fe15c4dba6beaf871cc0f
https://doi.org/10.1074/jbc.m702162200
https://doi.org/10.1074/jbc.m702162200