Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Longchang Jiang"'
Publikováno v:
Cells, Vol 11, Iss 9, p 1427 (2022)
KRAS is one well-established tumor-driver gene associated with cancer initiation, development, and progression. Nonetheless, comparative studies of the relevance of KRAS across diverse tumors remain sparse. We explored the KRAS expression and prognos
Externí odkaz:
https://doaj.org/article/9a5e4e2642194a90ba9f3dc4f31b37e9
Autor:
Chieh-Yang Cheng, Chang-Il Hwang, David C. Corney, Andrea Flesken-Nikitin, Longchang Jiang, Gülfem Meryem Öner, Robert J. Munroe, John C. Schimenti, Heiko Hermeking, Alexander Yu. Nikitin
Publikováno v:
Cell Reports, Vol 6, Iss 6, Pp 1000-1007 (2014)
The miR-34 family was originally found to be a direct target of p53 and is a group of putative tumor suppressors. Surprisingly, mice lacking all mir-34 genes show no increase in cancer formation by 18 months of age, hence placing the physiological re
Externí odkaz:
https://doaj.org/article/eb540098fec04f6a8ededd0404e03aaa
Autor:
Chieh-Yang Cheng, Chang-Il Hwang, David C. Corney, Andrea Flesken-Nikitin, Longchang Jiang, Gülfem Meryem Öner, Robert J. Munroe, John C. Schimenti, Heiko Hermeking, Alexander Yu. Nikitin
Publikováno v:
Cell Reports, Vol 12, Iss 12, p 2181 (2015)
Externí odkaz:
https://doaj.org/article/b2c16592bd084985a572ea2becd8d759
Autor:
Heiko Hermeking, Longchang Jiang
'Supplementary Methods Scoring of immunohistochemical detections Supplementary Figure S1 Related to Figure 1 Supplementary Figure S2 Related to Figure 3 Supplementary Figure S3 Gene Ontology and KEGG pathway analysis of up-regulated mRNAs Supplementa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c6b499268779f5251a82226e7d9bb6d
https://doi.org/10.1158/0008-5472.22412763.v1
https://doi.org/10.1158/0008-5472.22412763.v1
Autor:
Heiko Hermeking, Longchang Jiang
The p53-inducible miR-34a and miR-34b/c genes are frequently silenced in colorectal cancer. To address the in vivo relevance of miR-34a/b/c function for suppression of intestinal tumor formation, we generated ApcMin/+ mice with deletions of the miR-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::805087daeace6bf2a1a2e3c98844079a
https://doi.org/10.1158/0008-5472.c.6508509.v1
https://doi.org/10.1158/0008-5472.c.6508509.v1
Autor:
Rawlings Achangwa, Aikaterini Gatsiou, Raphael Patras, Ariane Fischer, Kimon Stamatelopoulos, Christos Kontogiannis, Marco Sachse, Dimitrios Delialis, Ageliki Laina, Georgios Georgiopoulos, Eleftherios Zormpas, Francesca Bonini, Heiko Hermeking, Konstantinos Stellos, Longchang Jiang, Larissa Pfisterer, Simon Tual-Chalot, Stefanie Dimmeler, Andreas M. Zeiher, Nikolaos I. Vlachogiannis
Publikováno v:
Atherosclerosis. 327:49-58
Preclinical data suggest that the ageing-induced miR-34a regulates vascular senescence. Herein we sought to assess whether the miR-34 family members miR-34a, miR-34b and miR-34c are involved in human arterial disease.Expression levels of miR-34a/b/c
Publikováno v:
Reviews in medical virologyREFERENCES. 32(6)
Some viral infections lead to tumourigenesis explained by a variety of underlying molecular mechanisms. Long non-coding RNAs (lncRNAs) have the potential to be added to this list due to their diverse mechanisms in biological functions and disease pro
Autor:
Longchang, Jiang, Liangbiao George, Hu
Publikováno v:
Oncology Letters
Gastric cancer is the second most common cause of cancer-associated death in Asia. The incidence and mortality rates of gastric cancer have markedly increased in the past few decades. Therefore, the identification of novel gastric cancer biomarkers a
Publikováno v:
Journal of Translational Science. 6
Publikováno v:
Gastroenterology. 153:505-520
Background & Aims In colorectal tumors, hypoxia causes resistance to therapy and promotes metastasis. Loss of the tumor suppressor p53 (encoded by TP53 ) provides cancer cells with a selective advantage under conditions of hypoxia, but little is know