Zobrazeno 1 - 10
of 204
pro vyhledávání: '"LongFei Jia"'
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Synaptic dysfunction with reduced synaptic protein levels is a core feature of Alzheimer’s disease (AD). Synaptic proteins play a central role in memory processing, learning, and AD pathogenesis. Evidence suggests that synaptic
Externí odkaz:
https://doaj.org/article/1170492fc4e04d97b1c19081ceed67f7
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Plasma amyloid-β (Aβ)42, phosphorylated tau (p-tau)181, and neurofilament light chain (NfL) are promising biomarkers of Alzheimer’s disease (AD). However, whether these biomarkers can predict AD in Chinese populations is yet to be fully
Externí odkaz:
https://doaj.org/article/8d845ef6b3b14dac8e326f1da4da33ca
Autor:
Wenwen Li, Yana Pang, Yan Wang, Fan Mei, Mengmeng Guo, Yiping Wei, Xinyue Li, Wei Qin, Wei Wang, Longfei Jia, Jianping Jia
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background The identification of pathogenic mutations in Alzheimer’s disease (AD) causal genes led to a better understanding of the pathobiology of AD. Familial Alzheimer’s disease (FAD) is known to be associated with mutations in the AP
Externí odkaz:
https://doaj.org/article/bc7fc09fd1e34b7bb4cc4f8c58b8509b
Autor:
Yuqiu Han, Qi Ling, Li Wu, Xiaosen Wang, Zhifei Wang, Jun Chen, Zhipeng Zheng, Ziyuan Zhou, Longfei Jia, Lanjuan Li, Baohong Wang
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTCurrent evidence indicates that the next-generation probiotic Akkermansia muciniphila (A. muciniphila) has therapeutic potential for nonalcoholic fatty liver disease (NAFLD), especially its inflammatory stage known as nonalcoholic steatohepat
Externí odkaz:
https://doaj.org/article/2466b12d8bd64e3cadcab74274ea9f98
Publikováno v:
Mathematics, Vol 12, Iss 7, p 1094 (2024)
In edge computing environments, limited storage and computational resources pose significant challenges to complex super-resolution network models. To address these challenges, we propose an agile super-resolution network via intelligent path selecti
Externí odkaz:
https://doaj.org/article/d25230a7fc204b8daabba74930060f86
Autor:
Meina Quan, Qi Wang, Wei Qin, Wei Wang, Fangyu Li, Tan Zhao, Tingting Li, Qiongqiong Qiu, Shuman Cao, Shiyuan Wang, Yan Wang, Hongmei Jin, Aihong Zhou, Jiliang Fang, Longfei Jia, Jianping Jia
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background Neuropsychology and imaging changes have been reported in the preclinical stage of familial Alzheimer’s disease (FAD). This study investigated the effects of APOEε4 and known pathogenic gene mutation on different cognitive doma
Externí odkaz:
https://doaj.org/article/e7b782a050fa4e239050aff5cd741110
Publikováno v:
IEEE Access, Vol 11, Pp 102340-102351 (2023)
This paper proposes a novel end-to-end controller for the lower-limb exoskeleton for human performance augmentation (LEHPA) systems based on deep reinforcement learning (E2EDRL). The model-free controller contains two control levels: the high-level c
Externí odkaz:
https://doaj.org/article/cbaef6baa1474651af41bb0dd68b1b6d
Publikováno v:
IEEE Access, Vol 11, Pp 36029-36040 (2023)
The lower-limb exoskeleton for human performance augmentation (LEHPA) in sensitivity amplification control (SAC) is vulnerable to model parameter uncertainties and unmodeled dynamics due to its large sensitivity to external disturbances resulting fro
Externí odkaz:
https://doaj.org/article/b4cc90fc5a9f4ea593c4edbbd86690b4
Autor:
Huimin Cai, Yana Pang, Qi Wang, Wei Qin, Cuibai Wei, Ying Li, Tingting Li, Fangyu Li, Qigeng Wang, Yan Li, Yiping Wei, Longfei Jia
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-10 (2022)
Abstract Background Neuronal- and astrocyte-derived exosomes have been identified as an optimal source for screening biomarkers for Alzheimer’s disease (AD). However, few studies focus on the bulk exosome population isolated from plasma of AD. This
Externí odkaz:
https://doaj.org/article/165c036d5935428787fe0c9d088d2f86
Publikováno v:
Applied Sciences, Vol 13, Iss 24, p 13334 (2023)
In this paper, a novel global time-varying path planning (GTVP) method is proposed. In the method, real-time paths can be generated based on tunable Bezier curves, which can realize obstacle avoidance of manipulators. First, finite feature points are
Externí odkaz:
https://doaj.org/article/9ae8cf37492c495fa5b28906db5c0022