Zobrazeno 1 - 10
of 6 907
pro vyhledávání: '"Long non-coding RNAs"'
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-27 (2024)
Abstract Autophagy is a cellular process that involves the degradation and recycling of cellular components, including damaged proteins and organelles. It is an important mechanism for maintaining cellular homeostasis and has been implicated in vario
Externí odkaz:
https://doaj.org/article/e1c3e451ebb040d7932fb2de7f15f321
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Objectives The purpose of this study was to investigate the significance of pyroptosis-related lncRNAs (PRlncRNA) in predicting prognoses and immune landscapes of patients with gastric adenocarcinoma (STAD). Methods Transcriptomic data and c
Externí odkaz:
https://doaj.org/article/f3a46ac416924bb78d8698efa432adcd
Autor:
Olga V. Kovaleva, Polina A. Podlesnaya, Ekaterina S. Kudinova, Valeria V. Mochalnikova, Nikolay E. Kushlinskii, Alexey N. Gratchev
Publikováno v:
Alʹmanah Kliničeskoj Mediciny, Vol 52, Iss 4, Pp 189-196 (2024)
Rationale: Long non-coding RNAs (lncRNAs) influence tumor cell properties during the onset and progression of lung malignancies; however, their diagnostic and prognostic significance has not been determined. We have previously shown that when non-sma
Externí odkaz:
https://doaj.org/article/ffe96e95ecd94f978e550508008dc21d
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-14 (2024)
Abstract N 6-methyladenosine (m6A) is involved in most biological processes and actively participates in the regulation of reproduction. According to recent research, long non-coding RNAs (lncRNAs) and their m6A modifications are involved in reproduc
Externí odkaz:
https://doaj.org/article/447e98e6d16e42e88b186590d7c82cb5
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Hyperactive RNA Polymerase I (Pol I) transcription is canonical in cancer, associated with malignant proliferation, poor prognosis, epithelial-mesenchymal transition, and chemotherapy resistance. Despite its significance, the mole
Externí odkaz:
https://doaj.org/article/54681d1495d3485995fd919957afd267
Publikováno v:
Hereditas, Vol 161, Iss 1, Pp 1-13 (2024)
Abstract Background N6-methyladenosine (m6A) and 5-methylcytosine (m5C) play a role in modifying long non-coding RNAs (lncRNAs) implicated in tumorigenesis and progression. This study was performed to evaluate prognostic value of m6A- and m5C-related
Externí odkaz:
https://doaj.org/article/834e099202e248a1a42d7519f0ebf762
Autor:
You Zuo, Jiaqian He, Zheng Zhou, Jingjing Sun, Can Ouyang, Hui Huang, Yajuan Wang, Hairong Liu, Simon H. Reed
Publikováno v:
Non-coding RNA Research, Vol 9, Iss 3, Pp 649-658 (2024)
In recent years, various long non-coding RNAs (lncRNAs) involved in DNA damage response (DDR) have been identified and studied to deepen our understanding. However, there are rare reports on the association between lncRNAs and base excision repair (B
Externí odkaz:
https://doaj.org/article/f6e460879406499fb1d08933b6cbb872
Autor:
Magda Spella, Eleftherios Bochalis, Katerina Athanasopoulou, Argyri Chroni, Irene Dereki, Giannoula Ntaliarda, Ifigeneia Makariti, Georgios Psarias, Caterina Constantinou, Vasiliki Chondrou, Argyro Sgourou
Publikováno v:
Non-coding RNA Research, Vol 9, Iss 3, Pp 759-771 (2024)
Epigenetic approaches in direct correlation with assessment of critical genetic mutations in non-small cell lung cancer (NSCLC) are currently very intensive, as the epigenetic components underlying NSCLC development and progression have attained high
Externí odkaz:
https://doaj.org/article/f54a70d529af471c9df8c0c72a7898b2
Publikováno v:
Non-coding RNA Research, Vol 10, Iss , Pp 70-90 (2025)
Recently, the various regulative functions of long non-coding RNAs (LncRNAs) have been well determined. Recently, the vital role of LncRNAs as gene regulators has been identified in the immune system, especially in the inflammatory response. All cell
Externí odkaz:
https://doaj.org/article/211ed49c89114f6aa26040e52476afd8
Autor:
Shuo Li, Zhaohan Xu, Shiyao Zhang, Huiling Sun, Xiaodan Qin, Lin Zhu, Teng Jiang, Junshan Zhou, Fuling Yan, Qiwen Deng
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 1, Pp 116-129 (2025)
Acute ischemic stroke is a clinical emergency and a condition with high morbidity, mortality, and disability. Accurate predictive, diagnostic, and prognostic biomarkers and effective therapeutic targets for acute ischemic stroke remain undetermined.
Externí odkaz:
https://doaj.org/article/2f65dbb01b3244d6b24aa644306657cb