Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Long Xin Gui"'
Autor:
Rui-Xing Wang, Rui-Lan He, Hai-Xia Jiao, Run-Tian Zhang, Jing-Yi Guo, Xiao-Ru Liu, Long-Xin Gui, Mo-Jun Lin, Zhi-Juan Wu
Publikováno v:
Pharmaceutical Biology, Vol 58, Iss 1, Pp 1055-1063 (2020)
Context Ginsenoside Rb1, the main active ingredient of ginseng, exhibits ex vivo depression of store-operated calcium entry (SOCE) and related vasoconstriction in pulmonary arteries derived from pulmonary hypertension (PH) rats. However, the in vivo
Externí odkaz:
https://doaj.org/article/903f3d8974614ea5918d59a448d58d8d
Publikováno v:
Cellular Physiology and Biochemistry, Vol 51, Iss 2, Pp 763-777 (2018)
Background/Aims: Vascular muscularity is a key event in vessel remodeling during pulmonary artery hypertension (PAH). Endothelial-mesenchymal transdifferentiation (EndMT) has been increasingly reported to play a role in disease occurrence. Galectin-3
Externí odkaz:
https://doaj.org/article/a5ae8ba9c8dc448498f80eef06cd9d61
Publikováno v:
Cellular Physiology and Biochemistry, Vol 49, Iss 1, Pp 172-189 (2018)
Background/Aims: Pulmonary arterial hypertension (PAH) is a severe and debilitating disease characterized by remodeling of the pulmonary vessels, which is driven by excessive proliferation and migration and apoptosis resistance in pulmonary artery sm
Externí odkaz:
https://doaj.org/article/1d52a1189da04517972d0a139ae5a23e
Publikováno v:
Cellular Physiology and Biochemistry, Vol 39, Iss 2, Pp 438-452 (2016)
Background/Aims: Alterations in intracellular Ca2+ concentration ([Ca2+]i) underlie the pathogenesis of various cardiovascular diseases. Caveolin-1 (Cav-1) is the primary functional protein associated with caveolae, which are invaginations in the pla
Externí odkaz:
https://doaj.org/article/4ea8b3dd797d42a1ab5f69785e8a66e8
Publikováno v:
Journal of hypertension. 40(10)
Vascular calcification has been considered as a potential therapeutic target in pulmonary hypertension. Mg2+ has a protective role against calcification. This study aimed to investigate whether Mg2+ could alleviate pulmonary hypertension by reducing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d9b7d5f4795f334fddad3721efeaad
https://pubmed.ncbi.nlm.nih.gov/36052522
https://pubmed.ncbi.nlm.nih.gov/36052522
Autor:
Gui-Feng Lu, Fei Geng, Li-Ping Deng, Da-Cen Lin, Yan-Zhen Huang, Su-Mei Lai, Yi-Chen Lin, Long-Xin Gui, James S.K. Sham, Mo-Jun Lin
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 79(11)
Background: Pulmonary arterial hypertension maintains rapid cell proliferation and vascular remodeling through metabolic reprogramming. Recent studies suggested that circRNAs play important role in pulmonary vascular remodeling and pulmonary arterial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5df3af293db10590feb1e5f25b52dc2c
https://pubmed.ncbi.nlm.nih.gov/35997022
https://pubmed.ncbi.nlm.nih.gov/35997022
Autor:
Jing-Yi Guo, Rui-Xing Wang, Zhi-Juan Wu, Rui-Lan He, Long-Xin Gui, Run-Tian Zhang, Mo-Jun Lin, Hai-Xia Jiao, Xiao-Ru Liu
Publikováno v:
Pharmaceutical Biology
article-version (VoR) Version of Record
Pharmaceutical Biology, Vol 58, Iss 1, Pp 1055-1063 (2020)
article-version (VoR) Version of Record
Pharmaceutical Biology, Vol 58, Iss 1, Pp 1055-1063 (2020)
Context Ginsenoside Rb1, the main active ingredient of ginseng, exhibits ex vivo depression of store-operated calcium entry (SOCE) and related vasoconstriction in pulmonary arteries derived from pulmonary hypertension (PH) rats. However, the in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2acab548db6101acd276012f3748e462
http://europepmc.org/articles/PMC7592893
http://europepmc.org/articles/PMC7592893
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-20 (2019)
Journal of Translational Medicine
Journal of Translational Medicine
Background Pulmonary artery hypertension (PAH), which is characterized by an increase in pulmonary circulation blood pressure, is a fatal disease, and its pathogenesis remains unclear. Methods In this study, RNA sequencing (RNA-seq), tandem mass tags
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d67f96be1e9e8801fb8c2113de111e9
http://link.springer.com/article/10.1186/s12967-019-1981-5
http://link.springer.com/article/10.1186/s12967-019-1981-5
Autor:
Xiao-Ling Zhuang, Fu-Rong Yan, Zhuang-Li Zhu, Da-Cen Lin, Long-Xin Gui, Mo-Jun Lin, Zhi-Juan Wu, Mu Yunping
Publikováno v:
Experimental Physiology. 104:932-945
New findings What is the central question of this study? The aim was to examine and compare the contributions of caveolin-1 to the contractile responses mediated by L-type voltage-dependent calcium channels, store-operated Ca2+ channels and receptor-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6621d375513f8766ebc4c71e88458686
https://doi.org/10.1113/ep086924
https://doi.org/10.1113/ep086924
Magnesium Supplementation Attenuates Pulmonary Hypertension via Regulation of Magnesium Transporters
Autor:
Long Xin Gui, Wei Jie Zhu, Ru Hui Yao, Dan Wang, Mo Jun Lin, Da Cen Lin, Kun Han Chuang, Zhuang Li Zhu, James S.K. Sham, Si Yi Zheng
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 77(2)
Pulmonary hypertension (PH) is characterized by profound vascular remodeling and altered Ca 2+ homeostasis in pulmonary arterial smooth muscle cells (PASMCs). Magnesium ion (Mg 2+ ), a natural Ca 2+ antagonist and a cofactor for numerous enzymes, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ad7a562bf6967b4a3c36131c41a8b2
https://pubmed.ncbi.nlm.nih.gov/33356397
https://pubmed.ncbi.nlm.nih.gov/33356397