Capsaicin 8% Patch in Painful Diabetic Peripheral Neuropathy: A Randomized, Double-Blind, Placebo-Controlled Study

Autor: Simpson, David M., Robinson-Papp, Jessica, Van, Joanna, Stoker, Malcolm, Jacobs, Hélène, Snijder, Robert J., Schregardus, Diederik S., Long, Stephen K., Lambourg, Bruno, Katz, Nathaniel

Publikováno v: In Journal of Pain January 2017 18(1):42-53

Antipsychotic drugs induce similar effects on the release of dopamine and noradrenaline in the medial prefrontal cortex of the rat brain

Autor: Long Stephen K, C.H Kruse, J. B. De Vries, P. de Boer, Bhc Westerink

Publikováno v: European Journal of Pharmacology, 27-33. ELSEVIER SCIENCE BV
STARTPAGE=27;ENDPAGE=33;ISSN=0014-2999;TITLE=European Journal of Pharmacology

In the present study we have compared the effects of the classical antipsychotic drug haloperidol and four different atypical antipsychotics (clozapine, risperidone, olanzapine, ziprasidone) on extracellular levels of dopamine and noradrenaline in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b646991bea08a7038e6790a69705ffb
https://doi.org/10.1016/s0014-2999(98)00711-0

ChemInform Abstract: New 1-Aryl-4-(biarylmethylene)piperazines as Potential Atypical Antipsychotics Sharing Dopamine D2-Receptor and Serotonin 5-HT1A-Receptor Affinities

Autor: Jan A.M van der Heyden, Feenstra Roelof W, Long Stephen K, W. Kuipers, Janpeter de Moes, Martin Tulp, Chris G. Kruse, Henk Kling, Jos J. Hofma

Publikováno v: ChemInform. 32

This paper describes the syntheses of several 1-aryl-4-(biarylmethylene)piperazines and the results of the determination of their affinity for D(2) and 5-HT(1A) receptors. A selection of these compounds was evaluated in vivo, resulting in the identif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c2f14f423d737a95aa1483014a46931f
https://doi.org/10.1002/chin.200151159

Potentiation of synaptic reflexes by D-serine in the rat spinal cord in vitro

Autor: R. Siarey, Long Stephen K, R.H. Evans

Publikováno v: European Journal of Pharmacology. 195:241-244

6-Cyano-7-nitroquinoxaline-2,3-dione (CNQX) (10 microM) depressed dorsal root-evoked ventral and dorsal root potentials of the in vitro immature rat spinal cord to 26.3 +/- 5.2 S.E.M. and 40.8 +/- 2.7% of control values respectively. These depressant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f094c7c340d0c2f5a3edac35a61cc7f4
https://doi.org/10.1016/0014-2999(91)90541-w

SAR study of 1-aryl-4-(phenylarylmethyl)piperazines as ligands for both dopamine D2 and serotonin 5-HT1A receptors showing varying degrees of (Ant)agonism. Selection of a potential atypical antipsychotic

Autor: Kruse Cornelis G, Martin Theodorus Maria Tulp, Adri van den Hoogenband, Johannes Antonius Maria Van Der Heyden, Cornelis Nicolaas Jozef Stroomer, Herman H. van Stuivenberg, Long Stephen K, Feenstra Roelof W

Publikováno v: Chemicalpharmaceutical bulletin. 54(9)

The syntheses of several 1-aryl-4-(arylpyridylmethyl)piperazines (4) and their affinities for dopamine D(2) and serotonin 5-HT(1A) receptors are described. The compounds were evaluated both in vitro and in vivo, resulting in the identification of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec61e84687eec35e410dcb51be9dd248
https://pubmed.ncbi.nlm.nih.gov/16946546