Zobrazeno 1 - 10 of 78 pro vyhledávání: '"Long Shan, Li"'
1
Akademický článek
Study on unseating prevention for multi-union long simply supported girder bridges under near-fault ground motions
Autor: Long-Shan Li, Ying-Xin Hui, Jie Wang, Ya-Jun Zhang
Publikováno v: Heliyon, Vol 10, Iss 17, Pp e36932- (2024)
Girder shifting is a common form of seismic damage for girder bridges. Unseating could occur when the displacement of the girder is too large, especially for bridges near faults, because the velocity impulse effect leads to greater displacement respo
Externí odkaz: https://doaj.org/article/bbf77d2aae634f358d24a4486fc769ae
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2
Akademický článek
Glucocorticoid mediated inhibition of LKB1 mutant non-small cell lung cancers
Autor: Kenneth E. Huffman, Long Shan Li, Ryan Carstens, Hyunsil Park, Luc Girard, Kimberley Avila, Shuguang Wei, Rahul Kollipara, Brenda Timmons, Jessica Sudderth, Nawal Bendris, Jiyeon Kim, Pamela Villalobos, Junya Fujimoto, Sandra Schmid, Ralph J. Deberardinis, Ignacio Wistuba, John Heymach, Ralf Kittler, Esra A. Akbay, Bruce Posner, Yuzhuo Wang, Stephen Lam, Steven A. Kliewer, David J. Mangelsdorf, John D. Minna
Publikováno v: Frontiers in Oncology, Vol 13 (2023)
The glucocorticoid receptor (GR) is an important anti-cancer target in lymphoid cancers but has been understudied in solid tumors like lung cancer, although glucocorticoids are often given with chemotherapy regimens to mitigate side effects. Here, we
Externí odkaz: https://doaj.org/article/12a85fec027a43f998070bed490eb234
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3
Akademický článek
An in vivo functional genomics screen of nuclear receptors and their co-regulators identifies FOXA1 as an essential gene in lung tumorigenesis
Autor: Suzie K. Hight, Allison Mootz, Rahul K. Kollipara, Elizabeth McMillan, Paul Yenerall, Yoichi Otaki, Long-Shan Li, Kimberley Avila, Michael Peyton, Jaime Rodriguez-Canales, Barbara Mino, Pamela Villalobos, Luc Girard, Patrick Dospoy, Jill Larsen, Michael A. White, John V. Heymach, Ignacio I. Wistuba, Ralf Kittler, John D. Minna
Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 8, Pp 294-310 (2020)
Using a mini-library of 1062 lentiviral shRNAs targeting 40 nuclear hormone receptors and 70 of their co-regulators, we searched for potential therapeutic targets that would be important during in vivo tumor growth using a parallel in vitro and in vi
Externí odkaz: https://doaj.org/article/482fd373bde3424183dc0e497a6a3920
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10
Data from Modulating Endogenous NQO1 Levels Identifies Key Regulatory Mechanisms of Action of β-Lapachone for Pancreatic Cancer Therapy
Autor: David A. Boothman, Jinming Gao, William G. Bornmann, Carlton C. Barnett, Rolf A. Brekken, Xian-Jin Xie, Jingsheng Yan, Biswanath Patra, Jieru Meng, Ying Dong, Erik A. Bey, Long Shan Li
Purpose: Pancreatic cancer is the fourth leading cause of cancer-related deaths, in which the 5-year survival rate is less than 5%. Current standard of care therapies offer little selectivity and high toxicity. Novel, tumor-selective approaches are d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e8c287a7a797c7acc5d103d8372da2
https://doi.org/10.1158/1078-0432.c.6520184.v1
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