Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Long N. Nguyen"'
Autor:
Madhuvanthi Chandrakanthan, Toan Quoc Nguyen, Zafrul Hasan, Sneha Muralidharan, Thiet Minh Vu, Aaron Wei Liang Li, Uyen Thanh Nha Le, Hoa Thi Thuy Ha, Sang-Ha Baik, Sock Hwee Tan, Juat Chin Foo, Markus R. Wenk, Amaury Cazenave-Gassiot, Federico Torta, Wei Yi Ong, Mark Yan Yee Chan, Long N. Nguyen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
The mechanisms by which platelets release sphingosine-1-phosphate (S1P) is not well characterized. Here the authors show that Mfsd2b is required for S1P release from both resting and activated platelets and that deletion of Mfsd2b impairs thrombotic
Externí odkaz:
https://doaj.org/article/e716e244e510455898a0ba23f1fb858d
Autor:
Mircea Radu Mihu, Jessica Roman-Sosa, Avanish K. Varshney, Eliseo A. Eugenin, Bhavikkumar P. Shah, Hiu Ham Lee, Long N. Nguyen, Allan J. Guimaraes, Bettina C. Fries, Joshua D. Nosanchuk, Luis R. Martinez
Publikováno v:
mBio, Vol 6, Iss 6 (2015)
ABSTRACT Methamphetamine (METH) is a major drug of abuse in the United States and worldwide. Furthermore, Staphylococcus aureus infections and METH use are coemerging public health problems. S. aureus is the single most important bacterial pathogen i
Externí odkaz:
https://doaj.org/article/29b381a64f41447fb82f5c1fdad62197
SPNS1 is required for the transport of lysosphingolipids and lysoglycerophospholipids from lysosomes
Autor:
Hoa T.T. Ha, Xuan T.A. Nguyen, Linh K. Vo, Nancy C.P. Leong, Siyi Liu, Dat T. Nguyen, Pei Yen Lim, Ya Jun Wu, Toan Q. Nguyen, Jeongah Oh, Markus R. Wenk, Amaury Cazenave-Gassiot, Wei Yi Ong, Long N. Nguyen
Accumulation of sphingolipids, especially sphingosines, in the lysosomes is attributed to the pathogenesis of several lysosomal storage diseases. In search for a lysosomal protein that mediates the release of sphingosines, we identified SPNS1 which s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40a5e3ce254f344f5c37720c8929c399
https://doi.org/10.1101/2022.12.14.520377
https://doi.org/10.1101/2022.12.14.520377
Autor:
Sneha Muralidharan, Long N. Nguyen, Thiet Minh Vu, Juat Chin Foo, Aaron Wei Liang Li, Mark Y. Chan, Toan Quoc Nguyen, Zafrul Hasan, Sang-Ha Baik, Madhuvanthi Chandrakanthan, Wei-Yi Ong, Amaury Cazenave-Gassiot, Markus R. Wenk, Sock Hwee Tan, Uyen Thanh Nha Le, Hoa Thi Thuy Ha, Federico Torta
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications
We recently discovered that Mfsd2b, which is the S1P exporter found in blood cells. Here, we report that Mfsd2b is critical for the release of all S1P species in both resting and activated platelets. We show that resting platelets store S1P in the cy
Autor:
Victor H. Erives, Melissa E. Munzen, Daniel Zamith-Miranda, Hazael Hernandez, Swetha Manepalli, Long N. Nguyen, Mohamed F. Hamed, Joshua D. Nosanchuk, Luis R. Martinez
Publikováno v:
Infect Immun
Methamphetamine (METH) is a major public health and safety problem in the United States. Chronic METH abuse is associated with a 2-fold-higher risk of HIV infection and, possibly, additional infections, particularly those that enter through the respi
Publikováno v:
Sixteenth International Conference on Tangible, Embedded, and Embodied Interaction.
Postnatal deletion of Spns2 prevents neuroinflammation without compromising blood vascular functions
Autor:
Zafrul Hasan, Toan Q. Nguyen, Brenda Wan Shing Lam, Jovi Hui Xin Wong, Caleb Cheng Yi Wong, Clarissa Kai Hui Tan, Jiabo Yu, Chung Hwee Thiam, Yongliang Zhang, Veronique Angeli, Long N. Nguyen
Publikováno v:
Cellular and molecular life sciences : CMLS. 79(11)
Protein Spinster homolog 2 (Spns2) is a sphingosine-1-phosphate (S1P) transporter that releases S1P to regulate lymphocyte egress and trafficking. Global deletion of Spns2 (Spns2
Publikováno v:
Cellular and Molecular Life Sciences. 79
Autor:
Thanh Nha Uyen Le, Toan Q. Nguyen, Pazhanichamy Kalailingam, Yen Thi Kim Nguyen, Viresh Krishnan Sukumar, Clarissa Kai Hui Tan, Farhana Tukijan, Ludovic Couty, Zafrul Hasan, Ilaria Del Gaudio, Markus R. Wenk, Amaury Cazenave-Gassiot, Eric Camerer, Long N. Nguyen
Publikováno v:
Cell Reports. 40:111208
Sphingosine-1-phosphate (S1P) is a potent lipid mediator that is secreted by several cell types. We recently showed that Mfsd2b is an S1P transporter from hematopoietic cells that contributes approximately 50% plasma S1P. Here we report the character
Autor:
Zafrul Hasan, Jasmine Fei Li Chin, Juat Chin Foo, Long N. Nguyen, Thiet Minh Vu, Toan Q. Nguyen, Farhana Tukijan, Federico Torta, Sneha Muralidharan
Publikováno v:
The Journal of Biological Chemistry
Sphingosine-1-phosphate (S1P) is a potent lipid mediator that exerts its activity via activation of five different G protein–coupled receptors, designated as S1P1–5. This potent lipid mediator is synthesized from the sphingosine precursor by two