Zobrazeno 1 - 10
of 215
pro vyhledávání: '"Long, Piao"'
Autor:
Yanmei Yuan, Junting Xu, Quanxin Jiang, Chuanxin Yang, Ning Wang, Xiaolong Liu, Hai-long Piao, Sijia Lu, Xianjing Zhang, Liu Han, Zhiyan Liu, Jiabin Cai, Fang Liu, Suzhen Chen, Junli Liu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-21 (2024)
Abstract Background Targeting ferroptosis has been identified as a promising approach for the development of cancer therapies. Monounsaturated fatty acid (MUFA) is a type of lipid that plays a crucial role in inhibiting ferroptosis. Ficolin 3 (FCN3)
Externí odkaz:
https://doaj.org/article/a0fde06c913349df8656e2b1aeadc564
Autor:
Ning Qu, Di Chen, Ben Ma, Lijun Zhang, Qiuping Wang, Yuting Wang, Hongping Wang, Zhaoxian Ni, Wen Wang, Tian Liao, Jun Xiang, Yulong Wang, Shi Jin, Dixin Xue, Weili Wu, Yu Wang, Qinghai Ji, Hui He, Hai-long Piao, Rongliang Shi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Although papillary thyroid cancer (PTC) has a good prognosis, its recurrence rate is high and remains a core concern in the clinic. Molecular factors contributing to different recurrence risks (RRs) remain poorly defined. Here, we perform an
Externí odkaz:
https://doaj.org/article/1e5b922cf46b435bb2da8b473872f075
Autor:
Jinghan Li, Daiwang Shi, Siyi Li, Xiang Shi, Yu Liu, Yi Zhang, Gebang Wang, Chenlei Zhang, Tian Xia, Hai-long Piao, Hong-Xu Liu
Publikováno v:
Cell Death and Disease, Vol 15, Iss 2, Pp 1-14 (2024)
Abstract Immunotherapy has become a prominent first-line cancer treatment strategy. In non-small cell lung cancer (NSCLC), the expression of PD-L1 induces an immuno-suppressive effect to protect cancer cells from immune elimination, which designates
Externí odkaz:
https://doaj.org/article/7f628e09e17f4d60891e9c3fea91ddce
Publikováno v:
Metabolites, Vol 14, Iss 11, p 641 (2024)
Background: Diabetic kidney disease (DKD) is a major complication of diabetes leading to kidney failure. Methods: This study investigates lipid metabolism profiles of long-standing DKD (LDKD, diabetes duration > 10 years) by integrative analysis of a
Externí odkaz:
https://doaj.org/article/28d9f3cb5c2445ce936bbaa4a1c44a25
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Integrins are transmembrane receptors that possess distinct ligand-binding specificities in the extracellular domain and signaling properties in the cytoplasmic domain. While most integrins have a short cytoplasmic tail, integrin β4 has a l
Externí odkaz:
https://doaj.org/article/b64da8b55c3f40ab995e40e4e3d19a65
Autor:
Yawei Wang, Di Chen, Yu Liu, Daiwang Shi, Chao Duan, Jinghan Li, Xiang Shi, Yong Zhang, Zhanwu Yu, Nan Sun, Wei Wang, Yegang Ma, Xiaohan Xu, Wuxiyar Otkur, Xiaolong Liu, Tian Xia, Huan Qi, Hai-long Piao, Hong-Xu Liu
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-16 (2023)
Abstract Multiple primary lung cancers (MPLCs) pose diagnostic and therapeutic challenges in clinic. Here, we orchestrated the cellular and spatial architecture of MPLCs by combining single-cell RNA-sequencing and spatial transcriptomics. Notably, we
Externí odkaz:
https://doaj.org/article/437bea4b8caa4c69bb243ec2c2f6744e
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Wuxiyar Otkur, Xiaolong Liu, Huan Chen, Siyi Li, Ting Ling, Hanchen Lin, Renyu Yang, Tian Xia, Huan Qi, Hai-Long Piao
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background and purpose: GPR35, a member of the orphan G-protein-coupled receptor, was recently implicated in colorectal cancer (CRC). However, whether targeting GPR35 by antagonists can inhibit its pro-cancer role has yet to be answered.Experimental
Externí odkaz:
https://doaj.org/article/d8d3f62a5eab4ece9a2bdea4fa48593b
Autor:
Chibuzo Sampson, Qiuping Wang, Wuxiyar Otkur, Haifeng Zhao, Yun Lu, Xiaolong Liu, Hai‐long Piao
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 3, Pp n/a-n/a (2023)
Abstract Ubiquitination is one of the most important post‐translational modifications which plays a significant role in conserving the homeostasis of cellular proteins. In the ubiquitination process, ubiquitin is conjugated to target protein substr
Externí odkaz:
https://doaj.org/article/ea82d39736a347f7b02784acd338036c
Autor:
Zhen Ning, Xin Guo, Xiaolong Liu, Chang Lu, Aman Wang, Xiaolin Wang, Wen Wang, Huan Chen, Wangshu Qin, Xinyu Liu, Lina Zhou, Chi Ma, Jian Du, Zhikun Lin, Haifeng Luo, Wuxiyar Otkur, Huan Qi, Di Chen, Tian Xia, Jiwei Liu, Guang Tan, Guowang Xu, Hai-long Piao
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Different deubiquitinases are associated to cancer development. Here, the authors show that PPARgamma is stabilized by USP22-mediated deubiquitination leading to lipid accumulation and promoting hepatocellular carcinoma.
Externí odkaz:
https://doaj.org/article/7a0b38d3c50c4e26bad4fb004f16686a