Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Lone Harild Ottesen"'
Autor:
Donald P. Bottaro, Ronnie T.P. Poon, Lone Harild Ottesen, Howard Kallender, Diptee A. Kulkarni, Kristen E. Raffensperger, Yuan Liu, Robert C. Gagnon, Donna S. Cox, Aaron Camp, Theeranun Sanpajit, Pei-Jer Chen, Wirote Lausoontornsiri, Chia-Jui Yen, Yee Chao, Wattana Sukeepaisarnjaroen, Riccardo Lencioni, Thomas C.C. Yau
Association of NR1I3 haplotype with TTP (Supplementary Online only). CAT/CAT carriers, median TTP 1.92 months vs 6.21 months for CAT/â^' or â^'/â^' carriers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd1825e834816ea73536b314c3936e9
https://doi.org/10.1158/1078-0432.22466073.v1
https://doi.org/10.1158/1078-0432.22466073.v1
Autor:
Donald P. Bottaro, Ronnie T.P. Poon, Lone Harild Ottesen, Howard Kallender, Diptee A. Kulkarni, Kristen E. Raffensperger, Yuan Liu, Robert C. Gagnon, Donna S. Cox, Aaron Camp, Theeranun Sanpajit, Pei-Jer Chen, Wirote Lausoontornsiri, Chia-Jui Yen, Yee Chao, Wattana Sukeepaisarnjaroen, Riccardo Lencioni, Thomas C.C. Yau
Purpose: This phase I/II single-arm study evaluated the safety, pharmacokinetics, pharmacodynamics, and activity of foretinib, an oral multikinase inhibitor of MET, ROS, RON, AXL, TIE-2, and VEGFR2, in the first-line setting in advanced hepatocellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd95dc8c9a5274b26a5becd46455754
https://doi.org/10.1158/1078-0432.c.6526233
https://doi.org/10.1158/1078-0432.c.6526233
Autor:
Donald P. Bottaro, Ronnie T.P. Poon, Lone Harild Ottesen, Howard Kallender, Diptee A. Kulkarni, Kristen E. Raffensperger, Yuan Liu, Robert C. Gagnon, Donna S. Cox, Aaron Camp, Theeranun Sanpajit, Pei-Jer Chen, Wirote Lausoontornsiri, Chia-Jui Yen, Yee Chao, Wattana Sukeepaisarnjaroen, Riccardo Lencioni, Thomas C.C. Yau
Table S1: Summary of pharmacokinetic parameters (days 1 and 15); Table S2: Significant changes in circulating biomarkers from baseline; Table S3: Multivariate models for selected covariates, Overall Survival.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c16b04d0a46f6015be121524d955e0
https://doi.org/10.1158/1078-0432.22466070
https://doi.org/10.1158/1078-0432.22466070
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 291:G8-G15
Our aim was to measure whole body energy expenditure after a mixed liquid meal, with and without simultaneous propranolol infusion, in patients with cirrhosis. We also wanted to investigate the effect of propranolol on substrate fluxes and oxygen upt
Publikováno v:
Liver. 21:350-356
Background/aims In healthy adults, serum insulin-like growth factor I (IGF-I), IGF binding protein 3 (IGFBP-3) and acid labile subunit (ALS) form a 150-kDa ternary complex under the control of growth hormone (GH). Approximately 80-90% of circulating
Publikováno v:
Journal of Hepatology. 26:1018-1025
The aim of the study was to evaluate the pharmacokinetics of octreotide in patients with cirrhosis compared to healthy volunteers.Seventeen patients with cirrhosis and nine normals received an intravenous bolus of octreotide (0.75 microgram/kg), foll
Autor:
Allan Flyvbjerg, Jan Frystyk, M Kiszka-Kanowitz, Lone Harild Ottesen, Henning Grønbæk, Flemming Bendtsen
Publikováno v:
Ottesen, L H, Frystyk, J, Kiska-Kanowitz, M, Grønbæk, H, Bendtsen, F & Flyvbjerg, A 2002, ' Effects of octreotide on serum insulin-like growth factor I and insulin-like growth factor binding proteins in patients with cirrhosis ' Scandinavian Journal of Clinical & Laboratory Investigation, vol. 62, pp. 39-48 .
Aarhus University
Ottesen, L H, Frystyk, J, Kiszka-Kanowitz, M, Grønbæk, H, Bendtsen, F & Flyvbjerg, A 2002, ' Effects of octreotide on serum insulin-like growth factor I and insulin-like growth factor binding proteins in patients with cirrhosis ', Scandinavian Journal of Clinical & Laboratory Investigation, vol. 62, no. 16, pp. 39-47 .
Aarhus University
Ottesen, L H, Frystyk, J, Kiszka-Kanowitz, M, Grønbæk, H, Bendtsen, F & Flyvbjerg, A 2002, ' Effects of octreotide on serum insulin-like growth factor I and insulin-like growth factor binding proteins in patients with cirrhosis ', Scandinavian Journal of Clinical & Laboratory Investigation, vol. 62, no. 16, pp. 39-47 .
Hyperinsulinaemia and reduced insulin sensitivity are common features in patients with cirrhosis. Octreotide, a long-acting somatostatin analogue, is used in cirrhotic patients in the treatment of bleeding oesophageal varices. Octreotide has potent e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af39fb51d1add167b374403ee5add3d
https://pure.au.dk/portal/da/publications/effects-of-octreotide-on-serum-insulinlike-growth-factor-i-and-insulinlike-growth-factor-binding-proteins-in-patients-with-cirrhosis(0cec90d0-9840-11da-bee9-02004c4f4f50).html
https://pure.au.dk/portal/da/publications/effects-of-octreotide-on-serum-insulinlike-growth-factor-i-and-insulinlike-growth-factor-binding-proteins-in-patients-with-cirrhosis(0cec90d0-9840-11da-bee9-02004c4f4f50).html
Autor:
Flemming Bendtsen, Lone Harild Ottesen, Marianne Kiszka-Kanowitz, Niels Kristian Aagaard, Allan Flyvbjerg, Michael Rehling, Erling B. Pedersen, Jens H. Henriksen
Publikováno v:
Ottesen, L H, Aagaard, N K, Kiszka-Kanowitz, M, Rehling, M, Henriksen, J H, Pedersen, E B, Flyvbjerg, A & Bendtsen, F 2001, ' Effects of a long-acting formulation of octreotide on renal function and renal sodium handling in cirrhotic patients with portal hypertension: a randomized, double-blind, controlled trial ', Hepatology, vol. 34, no. 3, pp. 471-477 . https://doi.org/10.1053/jhep.2001.26754
Octreotide seems to have a beneficial effect on variceal bleeding, and long-term administration for the prevention of rebleeding is currently being evaluated. Experimental studies have suggested a beneficial effect of chronic octreotide treatment on
Publikováno v:
Journal of Hepatology. 36:257-258
Autor:
Jens H. Henriksen, Flemming Bendtsen, Marianne Kiszka-Kanowitz, M. Rehling, Niels Kristian Aagaard, E.B. Pedersen, Allan Flyvbjerg, Lone Harild Ottesen
Publikováno v:
Journal of Hepatology. 34:17-18