Výsledky vyhledávání - "Lone A. Nazir"

Akademický článek

Trigonelline, a plant derived alkaloid prevents ultraviolet-B-induced oxidative DNA damage in primary human dermal fibroblasts and BALB/c mice via modulation of phosphoinositide 3-kinase-Akt-Nrf2 signalling axis

Autor: Malik A. Tanveer, Haroon Rashid, Lone A. Nazir, Sajida Archoo, Naiku H. Shahid, Gupta Ragni, Sheikh A. Umar, Sheikh A. Tasduq

Publikováno v: Experimental Gerontology, Vol 171, Iss , Pp 112028- (2023)

Background: DNA is the main target for UV-B-irradiation-induced skin photodamage and accounts for 90 % of all the non-melanoma skin cancers. Purpose: In this study, we explored the mechanistic basis of photoprotective effect of Trigonelline, a natura

Externí odkaz: https://doaj.org/article/a29ef5378c51443584465b269c36448e

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Akademický článek

Synthesis and anti-melanoma effect of 3-O-prenyl glycyrrhetinic acid against B16F10 cells via induction of endoplasmic reticulum stress-mediated autophagy through ERK/AKT signaling pathway

Autor: Lone A. Nazir, Naikoo H. Shahid, Kumar Amit, Sheikh A. Umar, Sharma Rajni, Sandip Bharate, Pyare L. Sangwan, Sheikh Abdullah Tasduq

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

Melanoma is an aggressive form of cancer with poor prognosis and survival rates and limited therapeutic options. Here, we report the anti-melanoma effect of 3-O-prenyl glycyrrhetinic acid (NPC-402), a derivative of glycyrrhtinic acid, from a reputed

Externí odkaz: https://doaj.org/article/7351b30b4b514060a6a6d31ada3874e8

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Akademický článek

Glycyrrhizic Acid Prevents Oxidative Stress Mediated DNA Damage Response through Modulation of Autophagy in Ultraviolet-B-Irradiated Human Primary Dermal Fibroblasts

Autor: Sheikh A. Umar, Malik A. Tanveer, Lone A. Nazir, Gupta Divya, Ram A. Vishwakarma, Sheikh A. Tasduq

Publikováno v: Cellular Physiology and Biochemistry, Vol 53, Iss 1, Pp 242-257 (2019)

Externí odkaz: https://doaj.org/article/73b9b3ba26184f9e9dc4ff65d0cb8fc1

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Akademický článek

Chemical chaperone 4-phenyl butyric acid (4-PBA) reduces hepatocellular lipid accumulation and lipotoxicity through induction of autophagy[S]

Autor: Ashraf U. Nissar, Love Sharma, Malik A. Mudasir, Lone A. Nazir, Sheikh A. Umar, Parduman R. Sharma, Ram A. Vishwakarma, Sheikh A. Tasduq

Publikováno v: Journal of Lipid Research, Vol 58, Iss 9, Pp 1855-1868 (2017)

Defective autophagy has been linked to lipotoxicity in several cellular models. We aimed to investigate autophagy in lipid-stimulated hepatoma (Huh7) cells and tested whether 4-phenyl butyric acid (4-PBA), a chemical chaperone, has a beneficial role

Externí odkaz: https://doaj.org/article/cb81a8799fcc4ae0a5aabeb979c3ae0d

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Akademický článek

A clinico-etiological profile of adult extrahepatic portal venous obstruction in patients from Northern India. Is it a novel subset of occult extrahepatic portal vein obstruction?

Autor: Zeeshan Ahmad Wani, Mir Mohamad Muzzafer, Khan Afaq Ahmad, Lone Shaheen Nazir

Publikováno v: Asian Journal of Medical Sciences, Vol 15, Iss 3, Pp 151-155 (2024)

Background: Extrahepatic portal vein obstruction (EHPVO) is caused by occlusion and cavernomatous transformation of the portal vein. The EHPVO is well characterized in children. However, the same is not valid for adults. We aimed to evaluate the clin

Externí odkaz: https://doaj.org/article/8039c86170dd432abeced5cfe8ed0944

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