Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Lon D. Ridgway"'
Publikováno v:
The Scientific World Journal, Vol 1, Pp 35-35 (2001)
Externí odkaz:
https://doaj.org/article/79333173bec14320a78e4b21499f33a9
Supplemental Figure 1. A. Western blot of purified preparations of human latent and active HPSE recombinant proteins showing distinct molecular weights, β-actin was probed as a loading control. M.W. standards were run in parallel with samples (left
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ecfcecd536495e05e1abc77d74036a
https://doi.org/10.1158/1541-7786.22517535.v1
https://doi.org/10.1158/1541-7786.22517535.v1
Publikováno v:
American Journal of Physiology-Cell Physiology. 297:C55-C65
Large conductance Ca2+-activated K+(BKCa) channels encoded by the Slo1 gene (also known as KCNMA1) are physiologically important in a wide range of cell types and form complexes with a number of other proteins that affect their function. We performed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b58a12bbd5637a922ec08500c2f8d154
https://doi.org/10.1152/ajpcell.00073.2009
https://doi.org/10.1152/ajpcell.00073.2009
Publikováno v:
Scopus-Elsevier
Chemoresistance is a major impediment to the successful treatment of cancer. It involves various mechanisms, including defects in the apoptosis program that is induced by anticancer drugs. To further explore the mechanisms underlying the development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::179a7b041c855a03a7d593be377505ba
https://doi.org/10.3727/096504003108748410
https://doi.org/10.3727/096504003108748410
Autor:
Jerry C. Goodman, Morris D. Groves, Wei Yin, Disha Kumar, Lixin Zhang, Lon D. Ridgway, Michael D. Wetzel, Dario Marchetti, Jason A. Ngo
Publikováno v:
Science Translational Medicine. 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2244b0dbb6773ce53fe46956a7c3cbd5
https://doi.org/10.1126/scitranslmed.3006376
https://doi.org/10.1126/scitranslmed.3006376
Autor:
Jason A. Ngo, Jerry C. Goodman, Disha Kumar, Wei Yin, Michael D. Wetzel, Morris D. Groves, Lixin Zhang, Lon D. Ridgway, Dario Marchetti
Publikováno v:
Science Translational Medicine. 5
Brain metastatic breast cancer (BMBC) is uniformly fatal and increasing in frequency. Despite its devastating outcome, mechanisms causing BMBC remain largely unknown. The mechanisms that implicate circulating tumor cells (CTCs) in metastatic disease,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a706f736886ee1ada8f119c562c19699
https://doi.org/10.1126/scitranslmed.3005109
https://doi.org/10.1126/scitranslmed.3005109
Publikováno v:
Molecular cancer research : MCR. 10(6)
Heparanase is the only mammalian endoglycosidase which has been widely implicated in cancer because of its capability to degrade heparan sulfate chains of heparan sulfate proteoglycans (HSPG). Specifically, the cell surface HSPG syndecan-1 and -4 (SD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a730a28403cb7f19da1c3490a80ad647
https://pubmed.ncbi.nlm.nih.gov/22513363
https://pubmed.ncbi.nlm.nih.gov/22513363
Publikováno v:
Experimental and therapeutic medicine. 2(2)
The pathogenesis of medulloblastoma (MB), the most common and aggressive brain tumor in children, is poorly understood. MB tumors respond to factors secreted by cerebellar Purkinje neurons, such as Sonic hedgehog (Shh) and Wingless-type MMTV integrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c1e685e16809449f028f6193b45a1ca
https://pubmed.ncbi.nlm.nih.gov/21442027
https://pubmed.ncbi.nlm.nih.gov/21442027
Mechanisms of brain metastatic melanoma (BMM) remain largely unknown. Understanding the modulation of signaling pathways that alter BMM cell invasion and metastasis is critical to develop new therapies for BMM. Heparanase has been widely implicated i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea2a4c61927e01f5006d6f5a56926515
https://europepmc.org/articles/PMC3007595/
https://europepmc.org/articles/PMC3007595/
Publikováno v:
Molecular pharmacology. 72(3)
Large-conductance Ca(2+)-activated K(+) (BK(Ca)) channels play an important role in the regulation of cell physiology in a wide variety of excitable and nonexcitable tissues. Filamin A is a conserved and ubiquitous actin-binding protein that forms pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ff867d9ad6c2c975b2772eeb35d96d
https://pubmed.ncbi.nlm.nih.gov/17586600
https://pubmed.ncbi.nlm.nih.gov/17586600