Dicationic Diarylfurans as Anti-Pneumocystis carinii Agents

Autor: Jarosław Spychała, Arvind Kumar, Lombardy Rj, Susan Jones, Christine C. Dykstra, W. D. Wilson, Zhou M, R R Tidwell, David W. Boykin, James Edwin Hall

Publikováno v: Journal of Medicinal Chemistry. 38:912-916

Seven dicationic 2,5-diarylfurans have been synthesized, and their interactions with poly(dA-dT) and the duplex oligomer d(CGCCAATTCGCG)2 were evaluated by Tm measurements. The inhibition of topoisomerase II isolated from Giardia lamblia, the inhibit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177d83b88e5abb22d2a78c56bdb0dc91
https://doi.org/10.1021/jm00006a009

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Synthesis and in vitro antiprotozoal activities of dicationic 3,5-diphenylisoxazoles.

Autor: Patrick DA; Department of Pathology and Laboratory Medicine, School of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599-7525, USA., Bakunov SA, Bakunova SM, Kumar EV, Lombardy RJ, Jones SK, Bridges AS, Zhirnov O, Hall JE, Wenzler T, Brun R, Tidwell RR

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2007 May 17; Vol. 50 (10), pp. 2468-85. Date of Electronic Publication: 2007 Apr 18.

Structure, DNA minor groove binding, and base pair specificity of alkyl- and aryl-linked bis(amidinobenzimidazoles) and bis(amidinoindoles).

Autor: Fairley TA; Division of Organic Chemistry, Burroughs Wellcome Co., Research Triangle Park, North Carolina 27709., Tidwell RR, Donkor I, Naiman NA, Ohemeng KA, Lombardy RJ, Bentley JA, Cory M

Publikováno v: Journal of medicinal chemistry [J Med Chem] 1993 Jun 11; Vol. 36 (12), pp. 1746-53.