Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lolita Stribinskiene"'
Publikováno v:
Cancer Chemotherapy and Pharmacology. 39:399-409
Protein kinase inhibitors have demonstrated potential for use in the therapy of human cancers, in particular leukemia. Staurosporine, a protein kinase inhibitor with broad specificity, enhances the cytotoxic effects of various antitumor agents with d
Autor:
Eric Sturges, Velvizhi Ranganathan, Monica L. Farnsworth, Richard B. Lock, Lolita Stribinskiene, Mary Jane Elliott, Kathleen M. Murphy
Publikováno v:
Cancer chemotherapy and pharmacology. 44(1)
Defective apoptotic mechanisms are considered to play a role in both the development of malignancy and resistance to chemotherapeutic drugs. The Bcl-2 family of proteins regulate the cellular commitment to survive or die when challenged with various
Publikováno v:
Cancer chemotherapy and pharmacology. 41(6)
A reduced capacity for apoptosis induction is considered to play a significant role both in the development of malignancy and in tumor cell resistance to chemotherapeutic drugs. The Bcl-2 oncoprotein inhibits apoptosis induced by antitumor agents at
Publikováno v:
International Journal of Oncology.
The inhibitor of oxidative phosphorylation, 2,4-dinitrophenol (DNP), abrogates etoposide cytotoxicity in murine leukemia L1210 cells without affecting the quantity of drug-induced DNA lesions. Cell cycle arrest and events associated with cell death w
Autor:
Elliott, Mary Jane, Murphy, Kathleen M., Stribinskiene, Lolita, Ranganathan, Velvizhi, Sturges, Eric, Farnsworth, Monica L., Lock, Richard B.
Publikováno v:
Cancer Chemotherapy & Pharmacology; May1999, Vol. 44 Issue 1, p1-11, 11p
Publikováno v:
Cancer Chemotherapy & Pharmacology; Mar1998, Vol. 41 Issue 6, p457-463, 7p
Publikováno v:
Cancer Chemotherapy & Pharmacology; Feb1997, Vol. 39 Issue 5, p399-409, 11p