Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Lolita Piersimoni"'
Publikováno v:
Physical Review Research, Vol 2, Iss 4, p 043260 (2020)
The field of quantum sensing aims at improving the detection and estimation of classical parameters that are encoded in physical systems by resorting to quantum sources of light and quantum detection strategies. The same approach can be used to impro
Externí odkaz:
https://doaj.org/article/62fe37e1d9194b8ba5b49c462ceaea1c
Autor:
Daniele Ubbiali, Marta Fratini, Lolita Piersimoni, Christian H. Ihling, Marc Kipping, Ingo Heilmann, Claudio Iacobucci, Andrea Sinz
Publikováno v:
Angewandte Chemie International Edition. 61
α-Synuclein (α-syn) is an intrinsically disordered protein (IDP) that undergoes liquid-liquid phase separation (LLPS), fibrillation, and forms insoluble intracellular Lewy bodies in neurons, which are the hallmark of Parkinson's Disease (PD). Neuro
Autor:
Daniele Ubbiali, Marta Fratini, Lolita Piersimoni, Christian H. Ihling, Marc Kipping, Ingo Heilmann, Claudio Iacobucci, Andrea Sinz
α-Synuclein (α-syn) is an intrinsically disordered protein (IDP) that undergoes liquid-liquid phase separation (LLPS), fibrillation, and forms insoluble intracellular Lewy’s bodies in neurons, which are the hallmark of Parkinson’s Disease (PD).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbb3d436d830f4481dda76d4793af399
https://doi.org/10.1101/2022.04.20.488894
https://doi.org/10.1101/2022.04.20.488894
Autor:
Lolita Piersimoni, Marina Abd el Malek, Twinkle Bhatia, Julian Bender, Christin Brankatschk, Jaime Calvo Sánchez, Guy W. Dayhoff, Alessio Di Ianni, Jhonny Oscar Figueroa Parra, Dailen Garcia-Martinez, Julia Hesselbarth, Janett Köppen, Luca M. Lauth, Laurin Lippik, Lisa Machner, Shubhra Sachan, Lisa Schmidt, Robin Selle, Ioannis Skalidis, Oleksandr Sorokin, Daniele Ubbiali, Bruno Voigt, Alice Wedler, Alan An Jung Wei, Peter Zorn, Alan Keith Dunker, Marcel Köhn, Andrea Sinz, Vladimir N. Uversky
Publikováno v:
Cellular and molecular life sciences : CMLS. 79(8)
Intrinsically disordered proteins and regions (IDPs and IDRs) and their importance in biology are becoming increasingly recognized in biology, biochemistry, molecular biology and chemistry textbooks, as well as in current protein science and structur
Autor:
Kelly A. Manthei, Wenmin Yuan, Anna Schwendeman, Jenny Capua Shenkar, Christopher J. Wilson, Dhabaleswar Patra, Melanie D. Ohi, Lolita Piersimoni, Philip C. Andrews, John J.G. Tesmer, John R. Engen, Maria V. Fawaz
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-11 (2020)
Communications Biology
Communications Biology
Lecithin:cholesterol acyltransferase (LCAT) catalyzes a critical step of reverse cholesterol transport by esterifying cholesterol in high density lipoprotein (HDL) particles. LCAT is activated by apolipoprotein A-I (ApoA-I), which forms a double belt
Publikováno v:
Chemical reviews. 122(8)
Mass spectrometry (MS) has become one of the key technologies of structural biology. In this review, the contributions of chemical cross-linking combined with mass spectrometry (XL-MS) for studying three-dimensional structures of proteins and for inv
Publikováno v:
Analytical chemistry. 93(33)
The combination of cross-linking/mass spectrometry (XL-MS) and ion mobility is still underexplored for conducting protein conformational and protein-protein interaction studies. We present a method for analyzing cross-linking mixtures on a timsTOF Pr
Autor:
Andrea Sinz, Lolita Piersimoni
Publikováno v:
Analytical and Bioanalytical Chemistry
Cross-linking/mass spectrometry (XL-MS) has come a long way. Originally, XL-MS was used to study relatively small, purified proteins. Meanwhile, it is employed to investigate protein-protein interactions on a proteome-wide level, giving snapshots of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f622117d624c036863a3a595af835918
Autor:
Lolita Piersimoni, Philip C. Andrews, Susan E. Hagen, Yafei Jin, Kun Liu, H. D. Hollis Showalter
Publikováno v:
Organic & Biomolecular Chemistry. 16:8245-8248
Two novel cyclic quaternary amine crosslinking probes are synthesized for structural mass spectrometry of protein complexes in solution and for analysis of protein interactions in organellar and whole cell extracts. Each exhibits high aqueous solubil
Autor:
Frank Schmidt, Claudio O. Gualerzi, Anna Brandi, Lolita Piersimoni, Roberto Spurio, Jean-Hervé Alix, Naser Aliye Feto
Publikováno v:
Nucleic Acids Research
Cold-stress in Escherichia coli induces de novo synthesis of translation initiation factors IF1, IF2 and IF3 while ribosome synthesis and assembly slow down. Consequently, the IFs/ribosome stoichiometric ratio increases about 3-fold during the first