Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Lolita O. Zamir"'
Autor:
Mei Dong, Qing-Wen Shi, Yu-Cheng Gu, Bin Cong, Françoise Sauriol, Shu‐Hong Yu, Lolita O. Zamir, Hiromasa Kiyota, Chang Hong Huo
Publikováno v:
Organic Letters. 10:701-704
Echinopines A (1) and B (2), novel sesquiterpenoids with an unprecedented rearranged skeleton named echinopane, were isolated from the roots of Echinops spinosus. The structures were elucidated by extensive spectroscopic analysis. The relative config
Publikováno v:
Phytochemistry. 65:3097-3106
Five taxanes with an amino-side chain on C-5 were identified for the first time in the needles of the Canadian yew, Taxus canadensis. Their structures were characterized as 2alpha,7beta,9alpha,10beta,13-pentaacetoxy-11beta-hydroxy-5alpha-(3'-N,N-dime
Publikováno v:
Tetrahedron Letters. 43:6869-6873
A novel minor metabolite 1 with an unprecedented skeleton was isolated from the needles of Taxus canadensis. A biogenesis from taxinine an abundant taxane is proposed. This is the first example of a taxane with a 6/6/8/6-membered ring skeleton.
Publikováno v:
Canadian Journal of Chemistry. 79:1381-1393
Reanalysis of the biotransformation of 4(20),11(12)-taxadiene derivatives by Absidia coerulea ATCC 10738a unravelled additional unprecedented rearrangement reactions. 5α,7β,9α,10β,13α-pentaacetoxy-4(20),11(12)-taxadiene (1) was converted to 10 n
Publikováno v:
Bioorganic & Medicinal Chemistry. 9:1985-1992
5alpha, 7beta, 9alpha, 10beta, 13alpha-Pentahydroxy-4(20),11(12)-taxadiene derivative 1 was converted to two unprecedented 1(15--11)abeo-taxanes and a taxane derivative with a C10-C11 double bond by Absidia coerula ATCC 10738a. A similar compound was
Autor:
Xiao-Li You, Francoise Sauriol, Orval Mamer, Moulay Alaoui-Jamali, Junzeng Zhang, Lolita O. Zamir, Gerald Batist
Publikováno v:
Journal of Natural Products. 64:450-455
Eight minor taxanes have been identified for the first time in Taxus canadensis needles. Four of these metabolites are new taxane analogues: 7-acetyl-10-deacetyltaxol (1), 2'-acetyl-7-epi-cephalomannine (2), 10-deacetyl-10-oxo-7-epi-cephalomannine (3
Autor:
Alice D. Cherestes, Gaétan Caron, Anastasia Nikolakakis, Lolita O. Zamir, Orval A. Mamer, Francoise Sauriol
Publikováno v:
Bioorganic & Medicinal Chemistry. 8:1269-1280
An efficient conversion of Taxus canadensis abundant taxane, 9-dihydro-13-acetylbaccatin III to baccatin III is described. Since the synthesis of paclitaxel from baccatin III has been reported, this work can be used for additional supply of this powe
Autor:
Lolita O. Zamir, Carole Abi Farah
Publikováno v:
Canadian Journal of Microbiology. 46:143-149
Fusarium spp. are ubiquitous fungi infecting cereals and grains, and therefore constitute a major problem for agriculture. Their trichothecene metabolites, and in particular deoxynivalenol and its 3-acetylated derivative, are the mycotoxins involved.
Publikováno v:
Tetrahedron. 55:14323-14340
Nineteen taxanes were characterized for the first time in the needles of the Canadian yew. Four of these metabolites are novel: taxinine-11, 12-oxide (1), 7-acetoxytaxuspine C (2), 5-cinnamoyltaxin B (3), and 7, 9-deacetyltaxinine B (4). Compound 1 i
Autor:
Anastasia Nikolakakis, Orval A. Mamer, Alice D. Cherestes, Françoise Sauriol, Lolita O. Zamir
Publikováno v:
Tetrahedron Letters. 40:7917-7920
The rearrangement of 9-dihydro-13-acetylbaccatin III, the major taxane from Taxus canadensis, has been studied. Two new cyclization products as well as one novel degradation compound are reported. Their structures were determined by spectroscopic tec