Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lolita Banerji"'
Autor:
Martin Sattler, Lolita Banerji
Publikováno v:
Expert Opinion on Therapeutic Targets. 8:221-239
Myeloid leukaemias are frequently associated with translocations and mutations of tyrosine kinase genes. The products of these oncogenes, including BCR-ABL, TEL-PDGFR, Flt3 and c-Kit, have elevated tyrosine kinase activity and transform haematopoieti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95171c6ff73533d04ad0e7b6da207600
https://doi.org/10.1517/14728222.8.3.221
https://doi.org/10.1517/14728222.8.3.221
Autor:
Inês Soeiro, Janet Glassford, Azim M Mohamedali, Ghulam J. Mufti, Eric Lam, Shaun Thomas, Nicholas Lea, Lolita Banerji
Publikováno v:
Journal of Leukocyte Biology. 74:1139-1143
Cyclin D2 affects B cell proliferation and differentiation in vivo. It is rate-limiting for B cell receptor (BCR)-dependent proliferation of B cells, and cyclin D2−/− mice lack CD5+(B1) B lymphocytes. We show here that the bone marrow (BM) of cyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b07499cab671ed74dc9ec9377bb2589
https://doi.org/10.1189/jlb.0803363
https://doi.org/10.1189/jlb.0803363
The influence of INK4 proteins on growth and self-renewal kinetics of hematopoietic progenitor cells
Autor:
Wimol Chinswangwatanakul, John M. Goldman, Eric Lam, Nicholas C.P. Cross, Bo Zheng, J. L. Lewis, N. Shaun B. Thomas, Janet Glassford, Stephen B. Marley, Lolita Banerji, Myrtle Y. Gordon, D. X. Nguyen
Publikováno v:
Blood. 97:2604-2610
This study investigated the influence of expression of proteins of the INK4 family, particularly p16, on the growth and self-renewal kinetics of hematopoietic cells. First, retrovirus-mediated gene transfer (RMGT) was used to restore p16INK4aexpressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aabee72867b8aa7fcd22a2821e16f17e
https://doi.org/10.1182/blood.v97.9.2604
https://doi.org/10.1182/blood.v97.9.2604
Autor:
Janet Glassford, Arnold R. Pizzey, B. Thomas, Eric Lam, Gerry G. B. Klaus, Lolita Banerji, N. Shaun, Jeroen van der Sman
Publikováno v:
European Journal of Immunology. 29:3380-3389
Since signals via CD40 and the B cell receptor are known to synergize to induce B cell activation, we have analyzed the pocket protein/E2F complexes in mouse B lymphocytes following stimulation by anti-IgM, anti-CD40, alone or together. We find that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c69858bb50cf28c9e9268bf62cd3389
https://doi.org/10.1002/(sici)1521-4141(199910)29:10<3380::aid-immu3380>3.0.co
https://doi.org/10.1002/(sici)1521-4141(199910)29:10<3380::aid-immu3380>3.0.co
Autor:
Renee D. Wright, Laurence Catley, Daisy Moreno, Lolita Banerji, Maira Sauveur-Michel, Ilene Galinsky, Andrew L. Kung, Ellen Weisberg, Rosemary Barrett, Richard Stone, Arghya Ray, Jingrui Jiang, James D. Griffin, Edward A. Fox, Elizabeth Hall-Meyers
Publikováno v:
Blood. 111(7)
Mediators of PI3K/AKT signaling have been implicated in chronic myeloid leukemia (CML) and acute myeloid leukemia (AML). Studies have shown that inhibitors of PI3K/AKT signaling, such as wortmannin and LY294002, are able to inhibit CML and AML cell p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be68db790f5f14d850ba3c24cbbed37
https://pubmed.ncbi.nlm.nih.gov/18184863
https://pubmed.ncbi.nlm.nih.gov/18184863
Autor:
Linda Callahan, Jingrui Jiang, Elizabeth Hall-Meyers, Arghya Ray, James D. Griffin, Lolita Banerji, Ellen Weisberg, Daisy Moreno, Jamie L. DellaGatta, Renee D. Wright, Juergen Mestan, Doriano Fabbro, Laurie Catley, Paul W. Manley, Andrew L. Kung
Publikováno v:
Blood. 109(5)
Drug resistance resulting from emergence of imatinib-resistant BCR-ABL point mutations is a significant problem in advanced-stage chronic myelogenous leukemia (CML). The BCR-ABL inhibitor, nilotinib (AMN107), is significantly more potent against BCR-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd3c905190f85c4431a9b16e8ced1d05
https://pubmed.ncbi.nlm.nih.gov/17409347
https://pubmed.ncbi.nlm.nih.gov/17409347
Autor:
Jonathan A. Fletcher, Sheng Xiao, Allison Coburn, Rachel Okabe, James D. Griffin, Ilene Galinsky, Ifor R. Williams, Benjamin H. Lee, Brian J. P. Huntly, Daniel J. DeAngelo, Richard Stone, Lolita Banerji, Jennifer Adelsperger, Pamela S. Cohen, Jeffery L. Kutok, Nicole Duclos, Martha Wadleigh, Jing Chen, Doriano Fabbro, D. Gary Gilliland, Sarah L. Cohen, Thomas F. Meyer, Johannes Roesel
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 101(40)
Human stem cell leukemia-lymphoma syndrome usually presents itself as a myeloproliferative disorder (MPD) that evolves to acute myeloid leukemia and/or lymphoma. The syndrome associated with t(8;13)(p11;q12) results in expression of the ZNF198-fibrob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6b7f49ad31cea313869c8aee0c7f13
https://pubmed.ncbi.nlm.nih.gov/15448205
https://pubmed.ncbi.nlm.nih.gov/15448205
Autor:
Eric Lam, Janet Glassford, Inês Soeiro, Shigeo Koyasu, Lolita Banerji, Gerry G. B. Klaus, Mary Holman, Takashi Kadowaki, Sara M Skarell
Publikováno v:
Oncogene. 22(15)
The p85alpha subunit of PI3-K and Btk are two crucial components of the B-cell receptor (BCR) signalling pathway. In the present study, we showed that primary splenic B cells from p85alpha null and xid (Btk-deficient) mice fail to induce cyclin D2 ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ff8c69ec6edd8ca7c6c9dfb867dfd8
https://pubmed.ncbi.nlm.nih.gov/12700661
https://pubmed.ncbi.nlm.nih.gov/12700661
Autor:
Gerry G. B. Klaus, Eric Lam, Elizabeth Clayton, Janet Glassford, Lolita Banerji, Martin R Turner, Mary Holman
Publikováno v:
The Journal of biological chemistry. 276(44)
B lymphocytes from mice null for the Rho-family guanine-nucleotide exchange factor, Vav, are defective in their ability to proliferate in response to BCR cross-linking, but are able to proliferate normally in response to LPS. In addition, they have a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777754708829523769385307c5687848
https://pubmed.ncbi.nlm.nih.gov/11546804
https://pubmed.ncbi.nlm.nih.gov/11546804
Publikováno v:
Oncogene. 20(50)
Cross-linking of the B cell antigen receptor (BCR) on immature WEHI 231 B cells results in G1 cell cycle arrest and apoptosis. Here we investigated the molecular mechanisms that are necessary and sufficient for these changes to occur. We show that BC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c32e5c7887842a0ef2281b7ecfd8cf
https://pubmed.ncbi.nlm.nih.gov/11704865
https://pubmed.ncbi.nlm.nih.gov/11704865