Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Loling Song"'
Autor:
Loling Song, Fabiana C. Morales, Gordon B. Mills, Marcin P. Iwanicki, Joan S. Brugge, Devin Worster, Laura M. Selfors, Taru A. Muranen, Sizhen Gao
Publikováno v:
Cancer Cell. 21(2):227-239
SummaryThe PI3K/mTOR-pathway is the most commonly dysregulated pathway in epithelial cancers and represents an important target for cancer therapeutics. Here, we show that dual inhibition of PI3K/mTOR in ovarian cancer-spheroids leads to death of inn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::150107488302792bad20a6431bc6b06a
Autor:
William F. Loomis, Sharvari M. Nadkarni, Albert Bae, Wouter-Jan Rappel, Carl Franck, Loling Song, Eberhard Bodenschatz, Hendrik U. Bödeker, Carsten Beta
Publikováno v:
European Journal of Cell Biology. 85:981-989
The chemotactic response of Dictyostelium discoideum cells to stationary, linear gradients of cyclic adenosine 3',5'-monophosphate (cAMP) was studied using microfluidic devices. In shallow gradients of less than 10(-3) nM/microm, the cells showed no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87d877afe5b4e92d5f0ca16504c29fa5
https://doi.org/10.1016/j.ejcb.2006.01.012
https://doi.org/10.1016/j.ejcb.2006.01.012
Publikováno v:
Cytometry. 27:213-223
The objective of this study was to identify, through kinetic analysis of individual elementary reactions, the conditions under which a simple first-order photobleaching kinetic model is sufficient for quantitative fluorescence measurements, and those
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82ef62fdd9cc1592c82446bb35c5e889
https://doi.org/10.1002/(sici)1097-0320(19970301)27:3<213::aid-cyto2>3.0.co
https://doi.org/10.1002/(sici)1097-0320(19970301)27:3<213::aid-cyto2>3.0.co
Autor:
Zachary T. Schafer, Pere Puigserver, Alexandra R. Grassian, Joan S. Brugge, Zhenyang Jiang, Zachary Gerhart-Hines, Sizhen Gao, Loling Song, Hanna Y. Irie
Normal epithelial cells require matrix attachment for survival, and the ability of tumour cells to survive outside their natural extracellular matrix (ECM) niches is dependent on acquisition of anchorage independence. Although apoptosis is the most r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1974155ab60201d331151ef33ac8af9
https://europepmc.org/articles/PMC2931797/
https://europepmc.org/articles/PMC2931797/
Autor:
Daniel S, Rhoads, Sharvari M, Nadkarni, Loling, Song, Camilla, Voeltz, Eberhard, Bodenschatz, Jun-Lin, Guan
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 294
In this chapter, we will discuss a method for the generation of gradients that can be quantitatively used for studying directional cell migration. Microfluidic networks, which serially split and remix small volumes of solutions under laminar flow con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4ed51e0bdf896849dc0a01c5aa745894
https://pubmed.ncbi.nlm.nih.gov/15576923
https://pubmed.ncbi.nlm.nih.gov/15576923
Autor:
Marcin P. Iwanicki, Joan S. Brugge, Devin Worster, Fabiana Morlaes, Taru E. Muranen, Loling Song, Gordon B. Mills, Laura M. Selfors
Publikováno v:
Cancer Research. 72:4836-4836
The PI3K/mTOR-pathway is the most commonly deregulated pathway in epithelial cancers and represents an important target for cancer therapeutics. Here we show that inhibition of PI3K/mTOR in ovarian and breast cancer 3D spheroids leads to death of inn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6b61054bcf427123a98f292d9ddec16
https://doi.org/10.1158/1538-7445.am2012-4836
https://doi.org/10.1158/1538-7445.am2012-4836
Autor:
Joan S. Brugge, Zachary Gerhart-Hines, Zachary T. Schafer, Grace Gao, Michael Overholtzer, Tobias Schmelzle, Loling Song, Yoko Irie, Arnaud Mailleux, Alex Grassian, Zhenyang Jiang, Pere Puigsever
Publikováno v:
Cancer Research. 69:IA-13
One of the earliest recognized features of tumor cells in culture is their ability to proliferate and survive without attachment to extracellular matrix. This ‘anchorage independence’ of tumor cells distinguishes their behavior from normal cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8100e66be912a4fe9910a99e4440d11
https://doi.org/10.1158/0008-5472.fbcr09-ia-13
https://doi.org/10.1158/0008-5472.fbcr09-ia-13
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