Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Lola Lecru"'
Autor:
Aurore Devocelle, Lola Lecru, Sophie Ferlicot, Thomas Bessede, Jean-Jacques Candelier, Julien Giron-Michel, Hélène François
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11698 (2021)
Chronic kidney disease (CKD), secondary to renal fibrogenesis, is a public health burden. The activation of interstitial myofibroblasts and excessive production of extracellular matrix (ECM) proteins are major events leading to end-stage kidney disea
Externí odkaz:
https://doaj.org/article/26fc4420e4744069839a34941a507dae
Autor:
Severine Beaudreuil, Xiaomeng Zhang, Florence Herr, Francis Harper, Jean Jacques Candelier, Ye Fan, Hilal Yeter, Caroline Dudreuilh, Lola Lecru, Aime Vazquez, Bernard Charpentier, Hans K Lorenzo, Antoine Durrbach
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219353 (2019)
IntroductionFocal and Segmental GlomeruloSclerosis (FSGS) can cause nephrotic syndrome with a risk of progression to end-stage renal disease. The idiopathic form has a high rate of recurrence after transplantation, suggesting the presence of a system
Externí odkaz:
https://doaj.org/article/571ac2ad55da488bac30158086a557db
Autor:
Aurore Devocelle, Lola Lecru, Hélène François, Christophe Desterke, Cindy Gallerne, Pierre Eid, Oberlin Estelle, Bruno Azzarone, Julien Giron-Michel
Publikováno v:
International Journal of Cell Biology, Vol 2019 (2019)
Renal tubulointerstitial fibrosis is the final common pathway in end-stage renal disease and is characterized by aberrant accumulation of extracellular matrix (ECM) components secreted by myofibroblasts. Tubular type 2 EMT, induced by TGF-β, plays a
Externí odkaz:
https://doaj.org/article/f2dd1266e67d4aff95707f65bb05433d
Autor:
Julien Giron-Michel, Sandy Azzi, Krystel Khawam, Erwan Mortier, Anne Caignard, Aurore Devocelle, Silvano Ferrini, Michela Croce, Hélène François, Lola Lecru, Bernard Charpentier, Salem Chouaib, Bruno Azzarone, Pierre Eid
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31624 (2012)
The ability of Interleukin-15 (IL-15) to activate many immune antitumor mechanisms renders the cytokine a good candidate for the therapy of solid tumors, particularly renal cell carcinoma. Although IL-15 is being currently used in clinical trials, th
Externí odkaz:
https://doaj.org/article/0da56d53568247f4b46971dd5cf814ee
Autor:
Nicolas Triballeau, Bertrand Heckmann, Nicolas Houvenaghel, Tanja Poljak, F. Marsais, Adeline Marie Elise Palisse, Emanuelle Wakselman, Mario Smehil, Mia Jans, Kathleen Sonck, Monica Borgonovi, Denis Bucher, Sandy El Bkassiny, Javier Blanc, Beatrice Coornaert, Thierry Christophe, Philippe Pujuguet, Vatroslav Letfus, M. Auberval, Lola Lecru, Laurent Saniere, Inge Duys, Reginald Brys, Line Oste, Brigitte Allart, Alex Jaunet, Maxim De Wachter, Catherine Jagerschmidt, Koen Karel Jansen, Oscar Mammoliti, Ludovic Waeckel, Giovanni Tricarico, Christel Jeanne Marie Menet, Renata Rupčić
Publikováno v:
Journal of medicinal chemistry. 64(19)
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease. Current treatments only slow down disease progression, making new therapeutic strategies compelling. Increasing evidence suggests that S1P2 antagonists could be effective
Autor:
Jean-Jacques Candelier, Hélène François, Thomas Bessede, Aurore Devocelle, Sophie Ferlicot, Julien Giron-Michel, Lola Lecru
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2021, 22 (21), pp.11698. ⟨10.3390/ijms222111698⟩
International Journal of Molecular Sciences, Vol 22, Iss 11698, p 11698 (2021)
Volume 22
Issue 21
International Journal of Molecular Sciences, MDPI, 2021, 22 (21), pp.11698. ⟨10.3390/ijms222111698⟩
International Journal of Molecular Sciences, Vol 22, Iss 11698, p 11698 (2021)
Volume 22
Issue 21
International audience; Chronic kidney disease (CKD), secondary to renal fibrogenesis, is a public health burden. The activation of interstitial myofibroblasts and excessive production of extracellular matrix (ECM) proteins are major events leading t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e966e55e7822fd46a7661493b261d67b
https://hal.sorbonne-universite.fr/hal-03447066/document
https://hal.sorbonne-universite.fr/hal-03447066/document
Autor:
Philippe Mateo, Mélanie Gressette, Arnaud Guilbert, Anne Garnier, Lola Lecru, Hélène François, Renée Ventura-Clapier, Maxance Ribeiro, Jérôme Piquereau, Pierre Eid, Céline Boursier, Cindy Gallerne, Julie Pires Da Silva, Dominique Fortin, Christophe Lemaire, Jane-Lise Samuel, Anaïs Caillard, David A. Sinclair, Alexandre Prola
Publikováno v:
Cell Death & Differentiation. 24:343-356
Over the past decade, endoplasmic reticulum (ER) stress has emerged as an important mechanism involved in the pathogenesis of cardiovascular diseases including heart failure. Cardiac therapy based on ER stress modulation is viewed as a promising aven
Autor:
Sophie Vandermeersch, Antoine Durrbach, Lola Lecru, Mélanie Ferreira, Christos Chatziantoniou, Bogdan Hermeziu, Katia Posseme, Hélène François, Myriam Dao, Charlotte Mussini, Sophie Ferlicot
Publikováno v:
Journal of Cellular and Molecular Medicine
Journal of Cellular and Molecular Medicine, Wiley Open Access, 2019, 23 (11), pp.7279-7288. ⟨10.1111/jcmm.14570⟩
Journal of Cellular and Molecular Medicine, Wiley Open Access, 2019, 23 (11), pp.7279-7288. ⟨10.1111/jcmm.14570⟩
International audience; Chronic allograft dysfunction (CAD), defined as the replacement of functional renal tissue by extracellular matrix proteins, remains the first cause of graft loss. The aim of our study was to explore the potential role of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58d744aeeb319ce67a3e71a9f9ae661b
https://hal.sorbonne-universite.fr/hal-02538112/file/jcmm.14570.pdf
https://hal.sorbonne-universite.fr/hal-02538112/file/jcmm.14570.pdf
Publikováno v:
Néphrologie & Thérapeutique. 12:S115-S122
Chronic kidney disease remains a major challenge for public health systems and corresponds to the replacement of renal functional tissue by extracellular matrix proteins such as collagens and fibronectin. There is no efficient treatment to date for c
Autor:
Hélène François, Lola Lecru
Publikováno v:
Current medicinal chemistry. 25(7)
Background Chronic kidney disease (CKD) remains a major challenge for Public Health systems and corresponds to the replacement of renal functional tissue by extra-cellular matrix proteins such as collagens and fibronectin. There is no efficient treat