Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events

Autor: Patel, RS, Schmidt, AF, Tragante, V, McCubrey, RO, Holmes, MV, Howe, LJ, Direk, K, Åkerblom, A, Leander, K, Virani, SS, Kaminski, KA, Muehlschlegel, JD, Dubé, M-P, Allayee, H, Almgren, P, Alver, M, Baranova, EV, Behlouli, H, Boeckx, B, Braund, PS, Breitling, LP, Delgado, G, Duarte, NE, Dufresne, L, Eriksson, N, Foco, L, Gijsberts, CM, Gong, Y, Hartiala, J, Heydarpour, M, Hubacek, JA, Kleber, M, Kofink, D, Kuukasjärvi, P, Lee, V-V, Leiherer, A, Lenzini, PA, Levin, D, Lyytikäinen, L-P, Martinelli, N, Mons, U, Nelson, CP, Nikus, K, Pilbrow, AP, Ploski, R, Sun, YV, Tanck, MWT, Tang, WHW, Trompet, S, Van Der Laan, SW, Van Setten, J, Vilmundarson, RO, Anselmi, C, Vlachopoulou, E, Boerwinkle, E, Briguori, C, Carlquist, JF, Carruthers, KF, Casu, G, Deanfield, J, Deloukas, P, Dudbridge, F, Fitzpatrick, N, Gigante, B, James, S, Lokki, M-L, Lotufo, PA, Marziliano, N, Mordi, IR, Muhlestein, JB, Newton-Cheh, C, Pitha, J, Saely, CH, Samman-Tahhan, A, Sandesara, PB, Teren, A, Timmis, A, Van De Werf, F, Wauters, E, Wilde, AAM, Ford, I, Stott, DJ, Algra, A, Andreassi, MG, Ardissino, D, Arsenault, BJ, Ballantyne, CM, Bergmeijer, TO, Bezzina, CR, Body, SC, Bogaty, P, De Borst, GJ, Brenner, H, Burkhardt, R, Carpeggiani, C, Condorelli, G, Cooper-Dehoff, RM, Cresci, S, De Faire, U, Doughty, RN, Drexel, H, Engert, JC, Fox, KAA, Girelli, D, Hagström, E, Hazen, SL, Held, C, Hemingway, H, Hoefer, IE, Hovingh, GK, Johnson, JA, De Jong, PA, Jukema, JW, Kaczor, MP, Kähönen, M, Kettner, J, Kiliszek, M, Klungel, OH, Lagerqvist, B, Lambrechts, D, Laurikka, JO, Lehtimäki, T, Lindholm, D, Mahmoodi, BK, Der Zee, AH, McPherson, R, Melander, O, Metspalu, A, Pepinski, W, Olivieri, O, Opolski, G, Palmer, CN, Pasterkamp, G, Pepine, CJ, Pereira, AC, Pilote, L, Quyyumi, AA, Richards, AM, Sanak, M, Scholz, M, Siegbahn, A, Sinisalo, J, Smith, JG, Spertus, JA, Stewart, AFR, Szczeklik, W, Szpakowicz, A, Berg, JM, Thanassoulis, G, Thiery, J, Van Der Graaf, Y, Visseren, FLJ, Waltenberger, J, Van Der Harst, P, Tardif, J-C, Sattar, N, Lang, CC, Paré, G, Brophy, JM, Anderson, JL, März, W, Wallentin, L, Cameron, VA, Horne, BD, Samani, NJ, Hingorani, AD, Asselbergs, FW

Genetic variation at chromosome 9p21 is a recognized risk factor for coronary heart disease (CHD). However, its effect on disease progression and subsequent events is unclear, raising questions about its value for stratification of residual risk.A va

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::86d67053a6d54128f7e80f8f66460c21
http://hdl.handle.net/11562/1028981

Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

Autor: Hinney, A., Kesselmeier, M., Huckins, Laura M, Hauser, Joanna, Karhunen, Leila, Meulenbelt, Ingrid, Slagboom, P Eline, Tortorella, Alfonso, Maj, Mario, Dedoussis, George, Dikeos, Dimitris, Gonidakis, Fragiskos, Tziouvas, Konstantinos, Southam, Lorraine, Tsitsika, Artemis, Papezova, Hana, Slachtova, Lenka, Martaskova, Debora, Kennedy, James L, Levitan, Robert D, Yilmaz, Zeynep, Huemer, Julia, Koubek, Doris, Merl, Elisabeth, Rayner, N William, Wagner, Gudrun, Lichtenstein, Paul, Breen, Gerome, Cohen-Woods, Sarah, Farmer, Anne, McGuffin, Peter, Cichon, Sven, Giegling, Ina, Herms, Stefan, Rujescu, Dan, Tachmazidou, Ioanna, Schreiber, Stefan, Wichmann, H-Erich, Dina, Christian, Sladek, Rob, Gambaro, Giovanni, Soranzo, Nicole, Julia, Antonio, Marsal, Sara, Rabionet, Raquel, Gaborieau, Valerie, Klump, Kelly L, Dick, Danielle M, Palotie, Aarno, Ripatti, Samuli, Widén, Elisabeth, Andreassen, Ole A, Espeseth, Thomas, Lundervold, Astri, Reinvang, Ivar, Steen, Vidar M, Hellard, Stephanie Le, Treasure, Janet, Mattingsdal, Morten, Ntalla, Ioanna, Bencko, Vladimir, Foretova, Lenka, Janout, Vladimir, Navratilova, Marie, Gallinger, Steven, Pinto, Dalila, Scherer, Stephen W, Aschauer, Harald, Lewis, Cathryn M, Carlberg, Laura, Schosser, Alexandra, Alfredsson, Lars, Ding, Bo, Klareskog, Lars, Padyukov, Leonid, Finan, Chris, Kalsi, Gursharan, Roberts, Marion, Logan, Darren W, Schmidt, Ulrike, Peltonen, Leena, Ritchie, Graham R S, Barrett, Jeff C, Estivill, Xavier, Hinney, Anke, Sullivan, Patrick F, Collier, David A, Zeggini, Eleftheria, Bulik, Cynthia M, Anderson, Carl A, Tozzi, Federica, Barrett, Jeffrey C, Floyd, James A B, Franklin, Christopher S, McGinnis, Ralph, Sambrook, Jennifer, Stephens, Jonathan, Ouwehand, Willem H, McArdle, Wendy L, iezebrink, Kirsty, Ring, Susan M, Strachan, David P, Alexander, Graeme, Conlon, Peter J, Dominiczak, Anna, Duncanson, Audrey, Hill, Adrian, Langford, Cordelia, Jall, S., Hebebrand, Johannes, Lord, Graham, Maxwell, Alexander P, Morgan, Linda, Sandford, Richard N, Sheerin, Neil, Vannberg, Frederik O, Blackburn, Hannah, Chen, Wei-Min, Edkins, Sarah, Gorwood, Philip, Gillman, Mathew, Gray, Emma, Hunt, Sarah E, Nengut-Gumuscu, Suna, Potter, Simon, Rich, Stephen S, Simpkin, Douglas, Whittaker, Pamela, Heid, I. 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Publikováno v: Molecular Psychiatry, 22, 2, pp. 192-201
Molecular psychiatry, 22(2), 192-201. Nature Publishing Group
Molecular Psychiatry, 22, 192. Nature Publishing Group
GCAN 2017, ' Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index ', Molecular Psychiatry, vol. 22, no. 2, pp. 192-201 . https://doi.org/10.1038/mp.2016.71
Molecular Psychiatry, 22(2), 192-201. Nature Publishing Group
Mol Psychiatry
Molecular Psychiatry, 22, 192-201
Hinney, A, Kesselmeier, M, Jall, S, Volckmar, A-L, Föcker, M, Antel, J, Heid, I M, Winkler, T W, Grant, S F A, Guo, Y, Bergen, A W, Kaye, W, Berrettini, W, Hakonarson, H, Herpertz-Dahlmann, B, de Zwaan, M, Herzog, W, Ehrlich, S, Zipfel, S, Egberts, K M, Adan, R, Brandys, M, van Elburg, A, Boraska Perica, V, Franklin, C S, Tschöp, M H, Zeggini, E, Bulik, C M, Collier, D, Scherag, A, Müller, T D, Hebebrand, J, GCAN, Hottenga, J J, Willemsen, G, Boomsma, D I, van Beijsterveldt, C E M, Middeldorp, C M & de Geus, E 2017, ' Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index ', Molecular Psychiatry, vol. 22, no. 2, pp. 192-201 . https://doi.org/10.1038/mp.2016.71
Molecular psychiatry 22(2), 192-201 (2017). doi:10.1038/mp.2016.71
Molecular psychiatry, vol 22, iss 2
Dipòsit Digital de la UB
Universidad de Barcelona
Molecular Psychiatry
Recercat. Dipósit de la Recerca de Catalunya
instname

The maintenance of normal body weight is disrupted in patients with anorexia nervosa (AN) for prolonged periods of time. Prior to the onset of AN, premorbid body mass index (BMI) spans the entire range from underweight to obese. After recovery, patie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe0fa762e65248741075d19c9dc455b2
https://hdl.handle.net/2066/169662

Lymphotoxin alpha LTA+496C allele is a risk factor for periodontitis in patients with coronary artery disease.

Autor: Palikhe, A.^1,2, Lokki, M.-L.², Pussinen, P. J.^3,4, Paju, S.^3,4, Ahlberg, J.⁴, Asikainen, S.⁵, Seppänen, M.⁶, Valtonen, V.⁶, Nieminen, M. S.¹, Sinisalo, J.¹ juha.sinisalo@hus.fi

Publikováno v: Tissue Antigens. Jun2008, Vol. 71 Issue 6, p530-537. 8p. 1 Color Photograph, 1 Diagram, 2 Charts.

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A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

Autor: Emmi Tikkanen, Elias Salfati, Majid Nikpay, Sonia S. Anand, Heribert Schunkert, Thomas Quertermous, George Dedoussis, Abbas Dehghan, Evelin Mihailov, Danish Saleheen, Lars Lannfelt, M. De Andrade, Daniel I. Chasman, Stanley L. Hazen, Vilmundur Gudnason, Christopher Grace, Christina Willenborg, Xueli Yang, Paul M. Ridker, Panos Deloukas, Hwang S-J., Eric Boerwinkle, Sekar Kathiresan, Lars Bertram, Kim B-J., Yun Kyoung Kim, Lokki M-L., Philippe M. Frossard, Adil Rasheed, Marc Haber, Alistair S. Hall, Kathleen Stirrups, Daniel J. Rader, Christopher B. Granger, Ingrid B. Borecki, Weihua Zhang, Thomas Meitinger, Liming Qu, Maris Alver, Wei Zhao, Samuli Ripatti, Andres Metspalu, Diego Ardissino, Memon F-U-R., Themistocles L. Assimes, Sebastian M. Armasu, Won H-H., L. A. Cupples, Tõnu Esko, Stephen M. Schwartz, Dongfeng Gu, Alanna C. Morrison, Han B-G., Nancy L. Pedersen, Tom R. Webb, Joachim Thiery, Marcus E. Kleber, Ligui Wang, J W Jukema, Thorsten Kessler, Xiangfeng Lu, Frank Beutner, Alison H. Goodall, Loukianos S. Rallidis, Natalia Pervjakova, Loos Rjf., Stavroula Kanoni, Leanne M. Hall, Patrik K. E. Magnusson, John C. Chambers, Christian Hengstenberg, Svati H. Shah, Olle Melander, Richa Saxena, Markus Perola, Alexandre F.R. Stewart, Jeanette Erdmann, Nadeem Hayyat Mallick, N. R. van Zuydam, Omri Gottesman, Jemma C. Hopewell, Hugh Watkins, John R. Thompson, Carlos Iribarren, Anders Hamsten, Rory Collins, Theodosios Kyriakou, Markus Scholz, Dharambir K. Sanghera, Jie Huang, Julie E. Buring, Christopher J. O'Donnell, Anuj Goel, Lynda M. Rose, Martin Farrall, Albert V. Smith, Lyytikäinen L-P., Winfried März, Muredach P. Reilly, Mary F. Feitosa, Andrew Bjonnes, Stella Trompet, John Danesh, Robert Roberts, Stefan Gustafsson, Christian Gieger, Ian Ford, Lingyao Zeng, Lars Lind, David J. Stott, Erik Ingelsson, Colin N. A. Palmer, Markku S. Nieminen, M Samuel, Annette Peters, Kirsi Auro, Dominique Gauguier, Narinder K. Mehra, Khan Shah Zaman, P. De Vries, Nilesh J. Samani, Inke R. König, Juha Sinisalo, Ilja Demuth, Pekka J. Karhunen, Wolfgang Lieb, Andrew P. Morris, Nora Franceschini, Veikko Salomaa, Robert Clarke, Erwin P. Bottinger, Roberto Elosua, Yingchang Lu, André G. Uitterlinden, Shapour Jalilzadeh, Cecilia M. Lindgren, Shufeng Chen, Terho Lehtimäki, Jaspal S. Kooner, Tamara B. Harris, Stephen E. Epstein, Udo Seedorf, Oscar H. Franco, Pierre Zalloua, King Wai Lau, Iftikhar J. Kullo, Albert Hofman, Christopher P. Nelson, MariaGrazia Franzosi, Ruth McPherson

Publikováno v: Nature Genetics, 47(10), 1121
Nature Genetics, 47(10), 1121-1130. Nature Publishing Group
Nature genetics
Nature Genetics

Existing knowledge of genetic variants affecting risk of coronary artery disease (CAD) is largely based on genome-wide association study (GWAS) analysis of common SNPs. Leveraging phased haplotypes from the 1000 Genomes Project, we report a GWAS meta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e125112055851368aa2c8ef11bf42dd
http://hdl.handle.net/1887/108152