Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Lokesh Joshi"'
Autor:
Christophe Penno, Mary O’Connell Motherway, Yuan Fu, Virag Sharma, Fiona Crispie, Paul D. Cotter, Benoit Houeix, Lokesh Joshi, Francesca Bottacini, Aoife O’Dwyer, Gary Loughran, John F. Atkins, Douwe van Sinderen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract The human gut microbiome, of which the genus Bifidobacterium is a prevalent and abundant member, is thought to sustain and enhance human health. Several surface-exposed structures, including so-called sortase-dependent pili, represent import
Externí odkaz:
https://doaj.org/article/bc3969c2a76447c09958da50179cacdf
Autor:
Anup Mammen Oommen, Stephen Cunningham, Páraic S. O’Súilleabháin, Brian M. Hughes, Lokesh Joshi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract In addition to the psychological depressive phenotype, major depressive disorder (MDD) patients are also associated with underlying immune dysregulation that correlates with metabolic syndrome prevalent in depressive patients. A robust integ
Externí odkaz:
https://doaj.org/article/7eae96b9cf37442c9578d13b6926dd7a
Publikováno v:
Biology, Vol 12, Iss 4, p 499 (2023)
Engagement of PRRs in recognition of PAMPs or DAMPs is one of the processes that initiates cellular stress. These sensors are involved in signaling pathways leading to induction of innate immune processes. Signaling initiated by PRRs is associated wi
Externí odkaz:
https://doaj.org/article/ac9b175dc6164493beb174c72e5be7d8
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1200 (2023)
The potential for psychedelic molecules in impacting cognitive flexibility has long been supported and acknowledged across scientific reports. In the current study, an approach leveraging knowledge-based gene-set information analysis has been adopted
Externí odkaz:
https://doaj.org/article/dcfc556af9ea42d6ab136ee372db89ae
Autor:
Shane Feeney, Jared Q. Gerlach, Helen Slattery, Michelle Kilcoyne, Rita M. Hickey, Lokesh Joshi
Publikováno v:
Food Science & Nutrition, Vol 7, Iss 5, Pp 1564-1572 (2019)
Abstract Immunoglobulin G (IgG) in bovine milk is credited with ensuring efficient passive immunity for newborn calves. Bovine milk IgG glycosylation may also have positive impacts on the health of nonbovine consumers of cow's milk. Milk IgG's glycos
Externí odkaz:
https://doaj.org/article/5dcbd0f328f8433d935beac59d5c403a
Autor:
Geraldine Leader, Cathal Abberton, Stephen Cunningham, Katie Gilmartin, Margo Grudzien, Emily Higgins, Lokesh Joshi, Sally Whelan, Arlene Mannion
Publikováno v:
Nutrients, Vol 14, Iss 7, p 1471 (2022)
This systematic review aims to offer an updated understanding of the relationship between gastrointestinal symptoms (GIS) and autism spectrum disorder (ASD) in children and adolescents. The databases PsycINFO, Medline, Cinahl, and ERIC were searched
Externí odkaz:
https://doaj.org/article/673926053ea9466fa6a9e99e68a348d1
Autor:
Anna Murphy, Krystyna Cwiklinski, Richard Lalor, Barry O'Connell, Mark W Robinson, Jared Gerlach, Lokesh Joshi, Michelle Kilcoyne, John P Dalton, Sandra M O'Neill
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 9, p e0008626 (2020)
Parasite-released extracellular vesicles (EVs) deliver signals to the host immune system that are critical to maintaining the long-term relationship between parasite and host. In the present study, total EVs (FhEVs) released in vitro by adults of the
Externí odkaz:
https://doaj.org/article/08a1b9fbcabb43ef9f37187856623a77
Autor:
Marta Utratna, Heidi Annuk, Jared Q. Gerlach, Yuan C. Lee, Marian Kane, Michelle Kilcoyne, Lokesh Joshi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract There is an urgent need for discovery of novel antimicrobials and carbohydrate-based anti-adhesive strategies are desirable as they may not promote resistance. Discovery of novel anti-adhesive molecules from natural product libraries will re
Externí odkaz:
https://doaj.org/article/6508bce32d4b4e14b2c19125fdd3ff0a
Autor:
Eduardo de la Torre-Escudero, Jared Q Gerlach, Adam P S Bennett, Krystyna Cwiklinski, Heather L Jewhurst, Kathryn M Huson, Lokesh Joshi, Michelle Kilcoyne, Sandra O'Neill, John P Dalton, Mark W Robinson
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 1, p e0007087 (2019)
Helminth parasites secrete extracellular vesicles (EVs) that can be internalised by host immune cells resulting in modulation of host immunity. While the molecular cargo of EVs have been characterised in many parasites, little is known about the surf
Externí odkaz:
https://doaj.org/article/9bdc6ecfce04429f878cefd3239720d4
Publikováno v:
Viruses, Vol 13, Iss 1, p 82 (2021)
Glycosylation, being the most abundant post-translational modification, plays a profound role affecting expression, localization and function of proteins and macromolecules in immune response to infection. Presented are the findings of a transcriptom
Externí odkaz:
https://doaj.org/article/4ec58b4723564a5f95825d25b4914de0