Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lokendrakumar C. Bengani"'
Autor:
Borja Salvador-Culla, Joseph B. Ciolino, Rekha Tulsan, Paraskevi E. Kolovou, Amy E. Ross, Lokendrakumar C. Bengani, Daniel S. Kohane, Sunil K. Chauhan, Hidenaga Kobashi, Hualei Zhai, Sharad K. Mittal
Publikováno v:
Acta Biomater
Ocular inflammation is one of the leading causes of blindness worldwide, and steroids in topical ophthalmic solutions (e.g. dexamethasone eye drops) are the mainstay of therapy for ocular inflammation. For many non-infectious ocular inflammatory dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ea5f24380c5792156d5a18dd3c0e6d
https://pubmed.ncbi.nlm.nih.gov/32814140
https://pubmed.ncbi.nlm.nih.gov/32814140
Publikováno v:
Cancer Research. 81:1706-1706
CpG-oligodeoxynucleotides (CpG ODNs) are known ligands of innate immune receptor, toll-like receptor 9 (TLR9). Activation of TLR9 by its ligands leads to stimulation of an immune cascade represented by secretion of Th1-type cytokine and chemokine mil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03bc2f5e42806fbf99beed6175c54944
https://doi.org/10.1158/1538-7445.am2021-1706
https://doi.org/10.1158/1538-7445.am2021-1706
Autor:
Borja Salvador-Culla, Manisha Mehta, Liangju Kuang, Paraskevi E. Kolovou, Koli Taghizadeh, Daniel S. Kohane, Daniel E. Maidana, Rehka Tulsan, Amy E. Ross, Joseph B. Ciolino, Hualei Zhai, Demetrios G. Vavvas, Hidenaga Kobashi, Lokendrakumar C. Bengani
Publikováno v:
Biomaterials. 217:119285
Intravitreal injections and implants are used to deliver drugs to the retina because therapeutic levels of these medications cannot be provided by topical administration (i.e. eye drops). In order to reach the retina, a topically applied drug encount
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca96c5c6105ee0384d9b00d56000b5cb
https://doi.org/10.1016/j.biomaterials.2019.119285
https://doi.org/10.1016/j.biomaterials.2019.119285
Publikováno v:
Expert Opinion on Drug Delivery. 10:1483-1496
Most ophthalmic drugs are delivered through eye drops even though only about 1 - 5% of the drug reaches the target tissue and the patient compliance is not good. Drug-eluting contact lenses could significantly increase bioavailability, reduce side ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebca3a533f26f1d0ae06f1d1b6287e64
https://doi.org/10.1517/17425247.2013.821462
https://doi.org/10.1517/17425247.2013.821462
Autor:
Chhavi Gupta, Lokendrakumar C. Bengani, Jenna L Leclerc, Cheng-Chun Peng, H.J. Jung, Anuj Chauhan
Publikováno v:
Journal of Drug Delivery Science and Technology. 21:111-121
Ocular drug delivery through aqueous eye drops is the most common approach for administering ophthalmic drugs, in spite of the low residence time of a few minutes, which limits the bioavailability to less than 5 %. A number of drug delivery approache
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcb52526a8fcb680564ab3e14ac7b741
https://doi.org/10.1016/s1773-2247(11)50010-3
https://doi.org/10.1016/s1773-2247(11)50010-3
Autor:
Anuj Chauhan, Lokendrakumar C. Bengani
Publikováno v:
Future Medicinal Chemistry. 4:2141-2143
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bb73a8fa9f8e8a4ab61b05f56545f2a
https://doi.org/10.4155/fmc.12.153
https://doi.org/10.4155/fmc.12.153
Autor:
Lokendrakumar C. Bengani, Anuj Chauhan
Publikováno v:
Biomaterials. 34(11)
Drug eluding contact lenses can be very effective vehicles for ophthalmic drug delivery, but are incapable of releasing drug for more than a few hours. We propose to optimize the interactions of the polymer matrix of the contact lens with the hydroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10cb02182021b0ffa6b91aac56b26bf1
https://pubmed.ncbi.nlm.nih.gov/23337326
https://pubmed.ncbi.nlm.nih.gov/23337326
Publikováno v:
Journal of colloid and interface science. 386(1)
Protein binding in hydrogels adversely affects their performance and can interfere with their usage in several biomedical applications including contact lenses. In this study we focus on understanding and modeling the mechanisms of protein transport
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e0b78bc6fadefa77c0ac367a5d6a33
https://pubmed.ncbi.nlm.nih.gov/22858395
https://pubmed.ncbi.nlm.nih.gov/22858395