Výsledky vyhledávání - "Lokanath Neratur Krishnappagowda"

Akademický článek

A novel pyrazole derivative as COVID-19 main protease inhibitor: Synthesis, quantum computational studies, pharmacokinetic properties, drug likeness, molecular docking and dynamics simulation; a CADD approach

Autor: D. Rekharani, Naveen Shivalingegowda, Mahesha, M.V. Deepa Urs, B.S. Chethan, Lokanath Neratur Krishnappagowda

Publikováno v: Chemical Physics Impact, Vol 8, Iss , Pp 100475- (2024)

2-(3‑bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl)-8-methyl-4H benzo[d][1,3]oxazin-4-one (2-BCBO) compound, was synthesized by the reaction of 3‑bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylic acid in acetonitrile and methane sulfonyl c

Externí odkaz: https://doaj.org/article/4e7f3b2b89764c1e8404cfb02df91f36

Zobrazit plný text záznamu

Akademický článek

Design and synthesis of coumarin-triazole hybrids: biocompatible anti-diabetic agents, in silico molecular docking and ADME screening

Autor: Vagish Channa Basappa, Vivek Hamse Kameshwar, Karthik Kumara, Dileep Kumar Achutha, Lokanath Neratur Krishnappagowda, Ajay Kumar Kariyappa

Publikováno v: Heliyon, Vol 6, Iss 10, Pp e05290- (2020)

The current study demonstrates the synthesis of coumarin-triazole hybrids 8 (a-e) in four steps starting from substituted salicylaldehyde 1 (a-e), and diethyl malonate 2. The spectroscopic studies provide the structure proofs of the new compounds, an

Externí odkaz: https://doaj.org/article/da968dceff3941c38f28b27cdbab727c

Zobrazit plný text záznamu