Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Lok Man J Law"'
Autor:
Zhigang Yi, Lindsey Sperzel, Cindy Nürnberger, Peter J Bredenbeek, Kirk J Lubick, Sonja M Best, Cristina T Stoyanov, Lok Man J Law, Zhenghong Yuan, Charles M Rice, Margaret R MacDonald
Publikováno v:
PLoS Pathogens, Vol 7, Iss 1, p e1001255 (2011)
Viruses in the Flavivirus genus of the Flaviviridae family are arthropod-transmitted and contribute to staggering numbers of human infections and significant deaths annually across the globe. To identify cellular factors with antiviral activity again
Externí odkaz:
https://doaj.org/article/bff01d06ed4c4506a6daef1243d5de93
Autor:
Margaret R. MacDonald, Melody M. H. Li, Charles M. Rice, Lok Man J. Law, Shihyun You, Andrea Jurado, Brandon S. Razooky
Publikováno v:
PLoS pathogens, vol 15, iss 5
PLoS Pathogens, Vol 15, Iss 5, p e1007798 (2019)
PLoS Pathogens
PLoS Pathogens, Vol 15, Iss 5, p e1007798 (2019)
PLoS Pathogens
Cellular antiviral programs encode molecules capable of targeting multiple steps in the virus lifecycle. Zinc-finger antiviral protein (ZAP) is a central and general regulator of antiviral activity that targets pathogen mRNA stability and translation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51dc9b55de09e6bd6c64bd3605528652
https://doi.org/10.1371/journal.ppat.1007798
https://doi.org/10.1371/journal.ppat.1007798
Publikováno v:
Emerging Microbes & Infections
New drugs to treat hepatitis C are expected to be approved over the next few years which promise to cure nearly all patients. However, due to issues of expected drug resistance, suboptimal activity against diverse hepatitis C virus (HCV) genotypes an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41af99d7dedec71f0102179d6fa68fe6
https://doi.org/10.1038/emi.2013.79
https://doi.org/10.1038/emi.2013.79
Publikováno v:
Journal of Virology. 77:1764-1771
Rubella virus is an enveloped positive-strand RNA virus of the family Togaviridae . Virions are composed of three structural proteins: a capsid and two membrane-spanning glycoproteins, E2 and E1. During virus assembly, the capsid interacts with genom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::707ab5a133aa6eb709be6178a62cea3c
https://doi.org/10.1128/jvi.77.3.1764-1771.2003
https://doi.org/10.1128/jvi.77.3.1764-1771.2003
Autor:
Ali Esmaili, Chris Hough, Sylvie Bertholet, Lok Man J. Law, Robert Duncan, Hira L. Nakhasi, Tom C. Hobman
Publikováno v:
Virology. 275(1):20-29
Rubella virus is an enveloped positive-strand RNA virus that can cause mild to severe birth defects or death in an infected fetus. RV induction of programmed cell death, demonstrated in cell culture, has been implicated in the pathogenesis. The timin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8774983fe62960f2336e4802c4cdeb41
Autor:
Charles M. Rice, Zhigang Yi, Cindy Nürnberger, Lindsey Sperzel, Peter J. Bredenbeek, Margaret R. MacDonald, Cristina Stoyanov, Lok Man J. Law, Kirk J. Lubick, Sonja M. Best, Zhenghong Yuan
Publikováno v:
PLoS Pathogens, 7(1)
PLoS Pathogens, Vol 7, Iss 1, p e1001255 (2011)
PLoS Pathogens
PLoS Pathogens, Vol 7, Iss 1, p e1001255 (2011)
PLoS Pathogens
Viruses in the Flavivirus genus of the Flaviviridae family are arthropod-transmitted and contribute to staggering numbers of human infections and significant deaths annually across the globe. To identify cellular factors with antiviral activity again
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f49682f2ad8806230f4538a435caa88
http://hdl.handle.net/1887/109123
http://hdl.handle.net/1887/109123
Autor:
Mark Kneteman, Andrew Mason, Don Graham, Min Chen, Suzanna Gilady, Guangzhi Zhang, Richard A. Flavell, Michael Trauner, Shawn T. Wasilenko, Stephen H. Wrzesinski, Mark G. Swain, Chelsea McDougall, Lok Man J. Law, Benchamas Subsin
Publikováno v:
Journal of hepatology. 55(4)
Background & Aims A human betaretrovirus resembling the mouse mammary tumor virus (MMTV) has been characterized in primary biliary cirrhosis (PBC) and associated with aberrant pyruvate dehydrogenase complex (PDC)–E2-like expression. As MMTV is prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::826ed71797596231ce8d1e8c9ce58d77
https://pubmed.ncbi.nlm.nih.gov/21334408
https://pubmed.ncbi.nlm.nih.gov/21334408
Autor:
Christopher T. Jones, Charles M. Rice, Margaret R. MacDonald, Lok Man J. Law, John-William N. Carroll, Owen R. Albin
Publikováno v:
Journal of virology. 84(9)
The zinc finger antiviral protein (ZAP) is a host factor with potent antiviral activity when overexpressed in cells. ZAP blocks replication of the prototype alphavirus Sindbis virus (SINV) at a step at or before translation of the incoming viral geno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be82856259e64eadedc5953fb01f7504
https://pubmed.ncbi.nlm.nih.gov/20181706
https://pubmed.ncbi.nlm.nih.gov/20181706
Autor:
Andrew J. Syder, John W. Schoggins, Salman R. Khetani, Charles M. Rice, Margaret R. MacDonald, Christopher T. Jones, Lok Man J. Law, Maria Teresa Catanese, Sangeeta N. Bhatia, Alexander Ploss, Thomas S. Oh
Publikováno v:
PMC
Author Manuscript 2010 August 1
Hepatitis C virus (HCV), which infects 2–3% of the world population, is a causative agent of chronic hepatitis and the leading indication for liver transplantation1. The ability to propagate HCV in cell culture
Hepatitis C virus (HCV), which infects 2–3% of the world population, is a causative agent of chronic hepatitis and the leading indication for liver transplantation1. The ability to propagate HCV in cell culture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a931fb5b12bfb0a39d74f0af076621a
https://pubmed.ncbi.nlm.nih.gov/20432262
https://pubmed.ncbi.nlm.nih.gov/20432262
The rubella virus (RV) structural proteins capsid, E2, and E1 are synthesized as a polyprotein precursor. The signal peptide that initiates translocation of E2 into the lumen of the endoplasmic reticulum remains attached to the carboxy terminus of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fbbc8882181328704fbce3d90eea4f5
https://europepmc.org/articles/PMC115144/
https://europepmc.org/articles/PMC115144/