Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Lois Yu En Sim"'
Autor:
Ruth Jinfen Chai, Hendrikje Werner, Peter Yiqing Li, Yin Loon Lee, Khaing Thet Nyein, Irina Solovei, Tuan Danh Anh Luu, Bhavya Sharma, Raju Navasankari, Martina Maric, Lois Yu En Sim, Ying Jie Loh, Edita Aliwarga, Jason Wen Long Cheong, Alexandre Chojnowski, Matias Ilmari Autio, Yu Haiyang, Kenneth Kian Boon Tan, Choong Tat Keng, Shi Ling Ng, Wei Leong Chew, Michael Ferenczi, Brian Burke, Roger Sik Yin Foo, Colin L. Stewart
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Mutations in the LaminA gene are the second most common inherited cause of Dilated Cardiomyopathy, a major form of heart failure. Here the authors show that disruption of the nuclear protein SUN1 in cardiomyocytes, by AAV mediated transduction of a S
Externí odkaz:
https://doaj.org/article/c8e8b6f93e7b442686a2d1ede70d7399
Autor:
Alexandre Chojnowski, Colin L. Stewart, Lois Yu En Sim, Yin Loon Lee, Choong Tat Keng, Matias Ilmari Autio, Tuan Danh Anh Luu, Ying Jie Loh, Khaing Thet Nyein, Roger Foo, Michael A. Ferenczi, Brian Burke, Shi Ling Ng, Kenneth Kian Boon Tan, Bhavya Sharma, Irina Solovei, Yu Haiyang, Jason Wen Long Cheong, Ruth Jinfen Chai, Peter Yiqing Li, Edita Aliwarga, Raju Navasankari, Martina Maric, Hendrikje Werner, Wei Leong Chew
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Mutations in the LaminA gene are a common cause of monogenic dilated cardiomyopathy. Here we show that mice with a cardiomyocyte-specific Lmna deletion develop cardiac failure and die within 3–4 weeks after inducing the mutation. When the same Lmna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6afa6944b68830856ba3cb421879425b
http://europepmc.org/articles/PMC8342462
http://europepmc.org/articles/PMC8342462