Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Lois Ramsey"'
Autor:
Gareth J.S. Jenkins, Harris Bernstein, George S. Watts, Carol Bernstein, Hana Holubec, Claire M. Payne, Richard E. Sampliner, Lois Ramsey, Harinder S. Garewal, Anil Prasad, Katerina Dvorak
Publikováno v:
The American Journal of Gastroenterology. 104:302-309
Barrett's esophagus (BE) is a metaplastic lesion characterized by replacement of the normal squamous epithelium by columnar intestinal epithelium containing goblet cells. It is speculated that this process is an adaptation to protect cells from compo
Autor:
Katerina Dvorak, Sylvan B. Green, Lois Ramsey, Richard E. Sampliner, Harinder S. Garewal, Harris Bernstein, Barbora Dvorakova, Anil Prasad, Bohuslav Dvorak, Melissa Chavarria, Hana Holubec, Cara L. Crowley-Weber, Claire M. Payne, Carol Bernstein
Publikováno v:
Clinical Cancer Research. 13:5305-5313
Objectives: The molecular factors contributing to the development of Barrett's esophagus (BE) are unclear. Our previous studies showed that BE tissues secrete interleukin-6 (IL-6) and express proteins associated with IL-6 signaling, including IL-6 re
Autor:
Katerina Dvorak, Naihsuan C. Guy, Melissa Chavarria, Sylvan B. Green, Richard E. Sampliner, Carol Bernstein, Harinder S. Garewal, Lois Ramsey, Harris Bernstein, Barbora Dvorakova, Claire M. Payne, Amanda Condon, Hana Holubec, Anil Prasad
Publikováno v:
Gut. 56:763-771
Background: Barrett’s oesophagus is a premalignant condition associated with an increased risk for the development of oesophageal adenocarcinoma (ADCA). Previous studies indicated that oxidative damage contributes to the development of ADCA. Object
Autor:
Harris Bernstein, Anil Prasad, Lois Ramsey, Ronnie Fass, Harinder S. Garewal, Claire M. Payne, Katerina Dvorak, Richard E. Sampliner
Publikováno v:
Annals of Surgery. 244:1031-1036
The aim of this study was to evaluate expression of cancer risk-associated biomarkers in columnar epithelium at squamocolumnar junctions produced by an ablation procedure and proton pump inhibitors in incompletely ablated Barrett's esophagus (BE) pat
Autor:
Harinder S. Garewal, Lois Ramsey, Megan Wilson, Anil Prasad, Carol Bernstein, Harris Bernstein, Hana Holubec, Claire M. Payne, James Warneke, Katerina Dvorakova
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology. 14:166-172
Pms2 protein is a component of the DNA mismatch repair complex responsible both for post-replication correction of DNA nucleotide mispairs and for early steps in apoptosis. Germline mutations in DNA mismatch repair genes give rise to hereditary non-p
Autor:
Hana Holubec, Natalia A. Ignatenko, Karen A. Blohm-Mangone, David G. Besselsen, Lois Ramsey, Harris Bernstein, Monique Dall'Agnol, Harinder S. Garewal, Claire M. Payne, Katerina Dvorak, Jose L. Padilla-Torres, Eugene W. Gerner, Haiyan Cui, Carol Bernstein
Publikováno v:
Inflammatory Bowel Diseases. 12:278-293
Background: A high-fat diet is a risk factor for the development of inflammatory bowel disease (IBD) in humans. Deoxycholate (DOC) is increased in the colonic contents in response to a high-fat diet. Thus, an elevated level of DOC in the colonic lume
Autor:
Hana Holubec, Anil Prasad, Harris Bernstein, Richard E. Sampliner, Katerina Dvorakova, Bohuslav Dvorak, Harinder S. Garewal, Ronnie Fass, Jessica A. Dominguez, Claire M. Payne, Haiyan Cui, Lois Ramsey, Carol Bernstein
Publikováno v:
Clinical Cancer Research. 10:2020-2028
Purpose: Barrett’s esophagus (BE) is a common premalignant lesion of the distal part of the esophagus that arises as a consequence of chronic duodenogastroesophageal reflux. Interleukin (IL)-6 is a pleiotropic cytokine that regulates immune defense
Autor:
Harris Bernstein, Ryan B. Chirnomas, Brandon D. Jeffy, Carol Bernstein, Donato F. Romagnolo, Lois Ramsey, Hana Holubec, Claire M. Payne, Achyut K. Bhattacharyya, James Warneke, Harinder S. Garewal, Kathleen Kunke, Jennifer Ku
Publikováno v:
Nutrition and Cancer. 46:82-92
Deoxycholate, a bile salt present at high levels in the colonic lumen of individuals on a high-fat diet, is a promoter of colon cancer. Deoxycholate also causes DNA damage. BRCA-1 functions in repair of DNA and in induction of apoptosis. We show that
Autor:
Lois Ramsey, Carol Bernstein, Claire M. Payne, Nancy K Hart, Harinder S. Garewal, Ronnie Fass, Harris Bernstein
Publikováno v:
Digestive Diseases and Sciences. 48:197-202
We assessed the immunohistochemical (IHC) staining patterns of three commercially available COX-2 antibodies in human tissues. The location of positive stain in sequential serial 4-μ sections of formalin fixed, paraffin embedded tissue differed cons
Publikováno v:
Journal of Cellular Biochemistry. 53:206-212
Because of the logistical and practical problems that make cancer prevention trials using cancer incidence as an endpoint virtually impossible to conduct for the majority of cancer types, there is a desperate need for valid intermediate markers of ca