Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lois E. Bolcsak"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 41:886-892
Amphotericin B lipid complex (ABLC) shows reduced toxicity relative to that of amphotericin B deoxycholate (AmB-d) while maintaining antifungal activity. Rat blood or plasma was spiked with ABLC in vitro. Released amphotericin B was separated from th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e02b66ad8db7f78ebee24b0d75965de1
https://doi.org/10.1128/aac.41.5.886
https://doi.org/10.1128/aac.41.5.886
Autor:
Lois E. Bolcsak, Christopher Cavanaugh, Amarnath Sharma, P. Harmon, Andrew S. Janoff, Eric Mayhew, Ralph J. Bernacki
Publikováno v:
International Journal of Cancer. 71:103-107
Although the current clinical formulation of paclitaxel (Taxol) is an important new anti-cancer agent, it has significant side effects, some of which are related to its formulation in Cremophor/ethanol. Paclitaxel is difficult to formulate for i.v. a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67c774b15f7f5261346dcd05453cd610
https://doi.org/10.1002/(sici)1097-0215(19970328)71:1<103::aid-ijc17>3.0.co
https://doi.org/10.1002/(sici)1097-0215(19970328)71:1<103::aid-ijc17>3.0.co
Autor:
Sol M. Gruner, Sharma R. Minchey, Michael J. Hope, Walter Perkins, Andrew S. Janoff, Lois E. Bolcsak, Lawrence T. Boni, Pieter R. Cullis
Publikováno v:
Chemistry and Physics of Lipids. 54:193-203
From freeze-fracture electron microscopy and x-ray diffraction we show that α-tocopherol hemisuccinate (α-THS) is capable of polymorphic phase behavior, including the formation of the hexagonal II phase. The transition from bilayer to hexagonal pha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21ebde6b15eb7d624c16e80d95049ae4
https://doi.org/10.1016/0009-3084(90)90012-g
https://doi.org/10.1016/0009-3084(90)90012-g
Publikováno v:
Journal of Antimicrobial Chemotherapy. 35:709-711
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e91acfcf2295d6ceeeb45e704ccd81b
https://doi.org/10.1093/jac/35.5.709
https://doi.org/10.1093/jac/35.5.709
Autor:
Lois E. Bolcsak, Rachel Stevens, Patricia Roberts, Rupinder Bhamra, Christine E. Swenson, Christopher Cavanaugh
Publikováno v:
Anti-cancer drugs. 14(3)
TLC ELL-12 is a liposomal formulation of the antineoplastic L-O.octadecyl-2-O-methyl-sn-glycero-3-phosphocholine [L-ET-18-OCH 3 (EL)]. The purpose of these studies was to characterize the toxicity and disposition of [N-methyl- 1 4 Cl L-ET-18-OCH 3 ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79a9fed3ca728e7ad7634bcaaab6125f
https://pubmed.ncbi.nlm.nih.gov/12634612
https://pubmed.ncbi.nlm.nih.gov/12634612
Autor:
Troy H. Guthrie, Katherine Tkaczuk, Philip Chaikin, Lauri Welles, Gerald Batist, Harold Boxenbaum, Rupinder Bhamra, Shein-Chung Chow, Christine E. Swenson, Lois E. Bolcsak
Publikováno v:
Anti-cancer drugs. 14(3)
Myocet (TLC D-99) is a liposomal formulation of the anti-neoplastic drug doxorubicin with an improved therapeutic index compared with conventional doxorubicin. The objective of this study was to assess the plasma disposition of doxorubicin when admin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d51574b1e3f0c07574af7cd753eb24d
https://pubmed.ncbi.nlm.nih.gov/12634619
https://pubmed.ncbi.nlm.nih.gov/12634619
Autor:
Christine E. Swenson, Lois E. Bolcsak, Andrew S. Janoff, Andrzej Hellmann, Adedayo Adedoyin, Gary Horwith, Robert A. Branch, Danuta Radowska
Publikováno v:
Antimicrobial agents and chemotherapy. 44(10)
This study describes a pharmacokinetic evaluation of amphotericin B (AMB) lipid complex injection (ABLC or Abelcet) in 17 patients with systemic fungal infection administered 5 mg/kg of body weight/day by infusion for 10 to 17 days. The results showe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f1865ac620c601f62d3101df642a7fb
https://pubmed.ncbi.nlm.nih.gov/10991885
https://pubmed.ncbi.nlm.nih.gov/10991885
Publikováno v:
Cellular Immunology. 46:213-218
Twenty three allophenic mice, produced by the aggregation of two 8-cell embryos, were examined by cytotoxicity testing for the proportions of parental cell types in their total splenic lymphocyte populations. Eleven (CBA × CBA/H-T6) ↔ C57BL/6 mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b426fa3909990cf5df7cba23b553952
https://doi.org/10.1016/0008-8749(79)90261-2
https://doi.org/10.1016/0008-8749(79)90261-2