Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Lois E H Smith"'
Autor:
Colin Niaudet, Bongnam Jung, Andrew Kuo, Steven Swendeman, Edward Bull, Takahiro Seno, Reed Crocker, Zhongjie Fu, Lois E H Smith, Timothy Hla
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 5, Pp 1-9 (2023)
Abstract Sphingosine‐1‐phosphate (S1P), the circulating HDL‐bound lipid mediator that acts via S1P receptors (S1PR), is required for normal vascular development. The role of this signaling axis in vascular retinopathies is unclear. Here, we sho
Externí odkaz:
https://doaj.org/article/baf615af7db14d7584f85d219c23d926
Autor:
Yan Gong, Jie Li, Ye Sun, Zhongjie Fu, Chi-Hsiu Liu, Lucy Evans, Katherine Tian, Nicholas Saba, Thomas Fredrick, Peyton Morss, Jing Chen, Lois E H Smith
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132643 (2015)
The mouse model of laser-induced choroidal neovascularization (CNV) has been used in studies of the exudative form of age-related macular degeneration using both the conventional slit lamp and a new image-guided laser system. A standardized protocol
Externí odkaz:
https://doaj.org/article/136e8f4b4b4c4bd1a2939aac52fd7a2e
Autor:
John Paul SanGiovanni, Jing Chen, Ankur S Gupta, Lois E H Smith, Przemyslaw Sapieha, Phil H Lee
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125548 (2015)
We conducted a nested candidate gene study and pathway-based enrichment analysis on data from a multi-national 77,000-person project on the molecular genetics of age-related macular degeneration (AMD) to identify AMD-associated DNA-sequence variants
Externí odkaz:
https://doaj.org/article/0a30bc5b3e1147eda263fd809d40804e
Autor:
Pia Lundgren, Anna Kistner, Eva M Andersson, Ingrid Hansen Pupp, Gerd Holmström, David Ley, Aimon Niklasson, Lois E H Smith, Carolyn Wu, Ann Hellström, Chatarina Löfqvist
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109460 (2014)
ObjectiveTo evaluate the impact of low birth weight as a risk factor for retinopathy of prematurity (ROP) that will require treatment in correlation with gestational age at birth (GA).Study designIn total, 2941 infants born ResultsUnivariate analysis
Externí odkaz:
https://doaj.org/article/4ded39077b124dbfa7977f960fec1721
Autor:
Shaday Michan, Aimee M Juan, Christian G Hurst, Zhenghao Cui, Lucy P Evans, Colman J Hatton, Dorothy T Pei, Meihua Ju, David A Sinclair, Lois E H Smith, Jing Chen
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85031 (2014)
Proliferative retinopathy is a leading cause of blindness, including retinopathy of prematurity (ROP) in children and diabetic retinopathy in adults. Retinopathy is characterized by an initial phase of vessel loss, leading to tissue ischemia and hypo
Externí odkaz:
https://doaj.org/article/9e52085956a84969910e9d7eead06e5e
Autor:
John Paul SanGiovanni, Jing Chen, Przemyslaw Sapieha, Christopher M Aderman, Andreas Stahl, Traci E Clemons, Emily Y Chew, Lois E H Smith
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53155 (2013)
Increased intake of ω-3 long-chain polyunsaturated fatty acids (LCPUFAs) and use of peroxisome proliferator activator receptor (PPAR)-activating drugs are associated with attenuation of pathologic retinal angiogenesis. ω-3 LCPUFAs are endogenous ag
Externí odkaz:
https://doaj.org/article/f19ea9ba486a443f84bac2dd10193ac2
Autor:
Zhuo Shao, Mollie Friedlander, Christian G Hurst, Zhenghao Cui, Dorothy T Pei, Lucy P Evans, Aimee M Juan, Houda Tahiri, François Duhamel, Jing Chen, Przemyslaw Sapieha, Sylvain Chemtob, Jean-Sébastien Joyal, Lois E H Smith
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69552 (2013)
Angiogenesis of the microvasculature is central to the etiology of many diseases including proliferative retinopathy, age-related macular degeneration and cancer. A mouse model of microvascular angiogenesis would be very valuable and enable access to
Externí odkaz:
https://doaj.org/article/f1702bd7523d451ea79e799da8f27bc0
Autor:
Jing Chen, Andreas Stahl, Nathan M Krah, Molly R Seaward, Jean-Sebastian Joyal, Aimee M Juan, Colman J Hatton, Christopher M Aderman, Roberta J Dennison, Keirnan L Willett, Przemyslaw Sapieha, Lois E H Smith
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30203 (2012)
Mutations in low-density lipoprotein receptor-related protein 5 (Lrp5) impair retinal angiogenesis in patients with familial exudative vitreoretinopathy (FEVR), a rare type of blinding vascular eye disease. The defective retinal vasculature phenotype
Externí odkaz:
https://doaj.org/article/b95b34056b594302b9b6d0fd3915b137
Autor:
Bertan Cakir, Yohei Tomita, Hitomi Yagi, Padraic Romfh, William Allen, Minji Ko, Peili Chen, Zhongjie Fu, Daryoosh Vakhshoori, Lois E H Smith
Publikováno v:
PNAS Nexus. 2
Eye diseases are diagnosed by visualizing often irreversible structural changes occurring late in disease progression, such as retinal ganglion cell loss in glaucoma. The retina and optic nerve head have high mitochondrial energy need. Early mitochon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cfb9007465ae158dc58650bcc4d24c3
https://doi.org/10.1093/pnasnexus/pgad148
https://doi.org/10.1093/pnasnexus/pgad148
Autor:
Zhongjie Fu, Pia Lundgren, Aldina Pivodic, Hitomi Yagi, Jarrod C. Harman, Jay Yang, Minji Ko, Katherine Neilsen, Saswata Talukdar, Ann Hellström, Lois E. H. Smith
Publikováno v:
Angiogenesis.
Hyperglycemia in early postnatal life of preterm infants with incompletely vascularized retinas is associated with increased risk of potentially blinding neovascular retinopathy of prematurity (ROP). Neovascular ROP (Phase II ROP) is a compensatory b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f319d63ebcfeac7f9ba7db36a0896168
https://doi.org/10.1007/s10456-023-09872-x
https://doi.org/10.1007/s10456-023-09872-x