Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lois A. Juergens"'
Publikováno v:
Cytometry. 2:291-297
DNA flow histogram analysis, using 33342 Hoechst as a stain, has been used to detect the effect of the potentially bifunctional alkylating agent, mitomycin C (MMC) on dermal fibroblasts from patients with Fanconi's anemia (FA), a hereditary human dis
Publikováno v:
Cancer Genetics and Cytogenetics. 1:187-196
The conditions necessary for energy transfer-enhanced chromosome banding are described and the results of chromosome staining produced by different energy donor-acceptor dye pairs are presented. Energy donors with A-T binding or fluorescence quantum
Publikováno v:
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 23(7)
A number of applications of the detection of deoxyribonucleic acid synthesis by fluorescence microscopy are illustrated. These include (a) the analysis of sister chromatid exchanges and sister chromatid segregation at mitosis, (b) the location of chr
Sister chromatid exchanges, which may reflect chromosome repair in response to certain types of DNA damage, provide a means of investigating the increased chromosome fragility characteristic of Fanconi's anemia. By a recently developed technique usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b867f6c3ab76d8bc62a844cc02ee1a
https://europepmc.org/articles/PMC433139/
https://europepmc.org/articles/PMC433139/
Autor:
Samuel A. Latt, K Gustashaw, Marc Lalande, Rhona Schreck, Lois A. Juergens, S Brefach, C. Dougherty, M Powers, T. N. Kaiser, Elhanan Sahar, A. Lojewski
Publikováno v:
Cytogenetics and cell genetics. 33(1-2)
Cells from patients with Fanconi’s anemia are unusually sensitive to agents which are capable of crosslinking DNA. This increased sensitivity can be detected both by cytogenetic and flow cytometric methods. An elevated frequency of chromosome aberr
Publikováno v:
Cytometry. 1(1)
A number of DNA-binding dyes, with spectral properties making them suitable as components of energy donor-acceptor pairs, are described. If such pairs are used to stain metaphase chromosomes, and if the energy acceptor (e.g., actinomycin D or methyl