Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study

Autor: Whelan, Christopher D, Altmann, Andre, Botía, Juan A, Jahanshad, Neda, Hibar, Derrek P, Absil, Julie, Alhusaini, Saud, Alvim, Marina K M, Auvinen, Pia, Bartolini, Emanuele, Bergo, Felipe P G, Bernardes, Tauana, Blackmon, Karen, Braga, Barbara, Caligiuri, Maria Eugenia, Calvo, Anna, Carr, Sarah J, Chen, Jian, Chen, Shuai, Cherubini, Andrea, David, Philippe, Domin, Martin, Foley, Sonya, França, Wendy, Haaker, Gerrit, Isaev, Dmitry, Keller, Simon S, Kotikalapudi, Raviteja, Kowalczyk, Magdalena A, Kuzniecky, Ruben, Langner, Soenke, Lenge, Matteo, Leyden, Kelly M, Liu, Min, Loi, Richard Q, Martin, Pascal, Mascalchi, Mario, Morita, Marcia E, Pariente, Jose C, Rodríguez-Cruces, Raul, Rummel, Christian, Saavalainen, Taavi, Semmelroch, Mira K, Severino, Mariasavina, Thomas, Rhys H, Tondelli, Manuela, Tortora, Domenico, Vaudano, Anna Elisabetta, Vivash, Lucy, von Podewils, Felix, Wagner, Jan, Weber, Bernd, Yao, Yi, Yasuda, Clarissa L, Zhang, Guohao, Bargalló, Nuria, Bender, Benjamin, Bernasconi, Neda, Bernasconi, Andrea, Bernhardt, Boris C, Blümcke, Ingmar, Carlson, Chad, Cavalleri, Gianpiero L, Cendes, Fernando, Concha, Luis, Delanty, Norman, Depondt, Chantal, Devinsky, Orrin, Doherty, Colin P, Focke, Niels K, Gambardella, Antonio, Guerrini, Renzo, Hamandi, Khalid, Jackson, Graeme D, Kälviäinen, Reetta, Kochunov, Peter, Kwan, Patrick, Labate, Angelo, McDonald, Carrie R, Meletti, Stefano, O'Brien, Terence J, Ourselin, Sebastien, Richardson, Mark P, Striano, Pasquale, Thesen, Thomas, Wiest, Roland, Zhang, Junsong, Vezzani, Annamaria, Ryten, Mina, Thompson, Paul M, Sisodiya, Sanjay M

Publikováno v: Whelan, Christopher D; Altmann, Andre; Botía, Juan A; Jahanshad, Neda; Hibar, Derrek P; Absil, Julie; Alhusaini, Saud; Alvim, Marina K M; Auvinen, Pia; Bartolini, Emanuele; Bergo, Felipe P G; Bernardes, Tauana; Blackmon, Karen; Braga, Barbara; Caligiuri, Maria Eugenia; Calvo, Anna; Carr, Sarah J; Chen, Jian; Chen, Shuai; Cherubini, Andrea; ... (2018). Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study. Brain, 141(2), pp. 391-408. Oxford University Press 10.1093/brain/awx341
Brain

Structural MRI abnormalities are inconsistently reported in epilepsy. In the largest neuroimaging study to date, Whelan et al. report robust structural alterations across and within epilepsy syndromes, including shared volume loss in the thalamus, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6fa24c634a85653d9a7e738412aa82
https://boris.unibe.ch/110715/1/awx341.pdf

Sensitivity of restriction spectrum imaging to memory and neuropathology in Alzheimer's disease

Autor: Reas, Emilie T, Hagler, Donald J, White, Nathan S, Kuperman, Joshua M, Bartsch, Hauke, Cross, Karalani, Loi, Richard Q, Balachandra, Akshara R, Meloy, MJ, Wierenga, Christina E, Galasko, Douglas, Brewer, James B, Dale, Anders M, McEvoy, Linda K

Publikováno v: Alzheimer's research & therapy, vol 9, iss 1
Reas, ET; Jr, HDJ; White, NS; Kuperman, JM; Bartsch, H; Cross, K; et al.(2017). Sensitivity of restriction spectrum imaging to memory and neuropathology in Alzheimer's disease. ALZHEIMERS RESEARCH & THERAPY, 9. doi: 10.1186/s13195-017-0281-7. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/4k53r5tr

BackgroundDiffusion imaging has demonstrated sensitivity to structural brain changes in Alzheimer's disease (AD). However, there remains a need for a more complete characterization of microstructural alterations occurring at the earliest disease stag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5367ef255c91cf1c273893a0301ffe34
https://escholarship.org/uc/item/4k53r5tr

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Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study.

Autor: Whelan CD; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, California, USA.; Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland., Altmann A; Translational Imaging Group, Centre for Medical Image Computing, University College London, London, UK., Botía JA; Reta Lila Weston Institute and Department of Molecular Neuroscience, UCL Institute of Neurology, London WC1N 3BG, UK., Jahanshad N; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, California, USA., Hibar DP; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, California, USA., Absil J; Department of Radiology, Hôpital Erasme, Universite Libre de Bruxelles, Brussels 1070, Belgium., Alhusaini S; Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.; Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada., Alvim MKM; Department of Neurology, University of Campinas, Campinas, Brazil., Auvinen P; Epilepsy Center, Department of Neurology, Kuopio University, Kuopio, Finland.; Institute of Clinical Medicine, Neurology, University of Eastern Finland, Kuopio, Finland., Bartolini E; Pediatric Neurology Unit, Children's Hospital A. Meyer-University of Florence, Italy.; IRCCS Stella Maris Foundation, Pisa, Italy., Bergo FPG; Department of Neurology, University of Campinas, Campinas, Brazil., Bernardes T; Department of Neurology, University of Campinas, Campinas, Brazil., Blackmon K; Comprehensive Epilepsy Center, Department of Neurology, New York University School of Medicine, New York, USA.; Department of Physiology, Neuroscience and Behavioral Science, St. George's University, Grenada, West Indies., Braga B; Department of Neurology, University of Campinas, Campinas, Brazil., Caligiuri ME; Institute of Molecular Bioimaging and Physiology of the National Research Council (IBFM-CNR), Catanzaro, Italy., Calvo A; Magnetic Resonance Image Core Facility, IDIBAPS, Barcelona, Spain., Carr SJ; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK., Chen J; Department of Computer Science and Engineering, The Ohio State University, USA., Chen S; Cognitive Science Department, Xiamen University, Xiamen, China.; Fujian Key Laboratory of the Brain-like Intelligent Systems, China., Cherubini A; Institute of Molecular Bioimaging and Physiology of the National Research Council (IBFM-CNR), Catanzaro, Italy., David P; Department of Radiology, Hôpital Erasme, Universite Libre de Bruxelles, Brussels 1070, Belgium., Domin M; Functional Imaging Unit, Institute of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany., Foley S; Cardiff University Brain Research Imaging Centre, School of Psychology, Wales, UK., França W; Department of Neurology, University of Campinas, Campinas, Brazil., Haaker G; Department of Neurosurgery, University Hospital, Freiburg, Germany.; Department of Neuropathology, University Hospital Erlangen, Germany., Isaev D; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, California, USA., Keller SS; Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, UK., Kotikalapudi R; Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; Department of Diagnostic and Interventional Neuroradiology, University of Tübingen, Tübingen, Germany., Kowalczyk MA; The Florey Institute of Neuroscience and Mental Health, Austin Campus, Melbourne, VIC, Australia., Kuzniecky R; Comprehensive Epilepsy Center, Department of Neurology, New York University School of Medicine, New York, USA., Langner S; Functional Imaging Unit, Institute of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany., Lenge M; Pediatric Neurology Unit, Children's Hospital A. Meyer-University of Florence, Italy., Leyden KM; Multimodal Imaging Laboratory, University of California San Diego, San Diego, California, USA.; Department of Psychiatry, University of California San Diego, San Diego, California, USA., Liu M; Neuroimaging of Epilepsy Laboratory, Montreal Neurological Institute and Hospital, Mcgill University, Montreal, Quebec, Canada., Loi RQ; Multimodal Imaging Laboratory, University of California San Diego, San Diego, California, USA.; Department of Psychiatry, University of California San Diego, San Diego, California, USA., Martin P; Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Mascalchi M; Neuroradiology Unit, Children's Hospital A. Meyer, Florence, Italy.; 'Mario Serio' Department of Experimental and Clinical Biomedical Sciences, University of Florence, Italy., Morita ME; Department of Neurology, University of Campinas, Campinas, Brazil., Pariente JC; Magnetic Resonance Image Core Facility, IDIBAPS, Barcelona, Spain., Rodríguez-Cruces R; Instituto de Neurobiología, Universidad Nacional Autónoma de México. Querétaro, Querétaro, México., Rummel C; Support Center for Advanced Neuroimaging (SCAN), University Institute for Diagnostic and Interventional Neuroradiology, Inselspital, University of Bern, Bern, Switzerland., Saavalainen T; Institute of Clinical Medicine, Neurology, University of Eastern Finland, Kuopio, Finland.; Central Finland Central Hospital, Medical Imaging Unit, Jyväskylä, Finland., Semmelroch MK; The Florey Institute of Neuroscience and Mental Health, Austin Campus, Melbourne, VIC, Australia., Severino M; Neuroradiology Unit, Department of Head and Neck and Neurosciences, Istituto Giannina Gaslini, Genova, Italy., Thomas RH; Institute of Psychological Medicine and Clinical Neurosciences, Hadyn Ellis Building, Maindy Road, Cardiff, UK.; Department of Neurology, University Hospital of Wales, Cardiff, UK., Tondelli M; Department of Biomedical, Metabolic, and Neural Science, University of Modena and Reggio Emilia, NOCSE Hospital, Modena, Italy., Tortora D; Neuroradiology Unit, Department of Head and Neck and Neurosciences, Istituto Giannina Gaslini, Genova, Italy., Vaudano AE; Department of Biomedical, Metabolic, and Neural Science, University of Modena and Reggio Emilia, NOCSE Hospital, Modena, Italy., Vivash L; Melbourne Brain Centre, Department of Medicine, University of Melbourne, Parkville, VIC, 3052, Australia.; Department of Neurology, Royal Melbourne Hospital, Parkville, 3050, Australia., von Podewils F; Department of Neurology, University Medicine Greifswald, Greifswald, Germany., Wagner J; Department of Epileptology, University Hospital Bonn, Bonn, Germany.; Department of Neurology, Philips University of Marburg, Marburg Germany., Weber B; Department of Epileptology, University Hospital Bonn, Bonn, Germany.; Department of Neurocognition / Imaging, Life&Brain Research Centre, Bonn, Germany., Yao Y; The Affiliated Chenggong Hospital of Xiamen University, Xiamen, China., Yasuda CL; Department of Neurology, University of Campinas, Campinas, Brazil., Zhang G; Department of Computer Science and Electrical Engineering, University of Maryland, Baltimore County, USA., Bargalló N; Magnetic Resonance Image Core Facility, IDIBAPS, Barcelona, Spain.; Centre de Diagnostic Per la Imatge (CDIC), Hospital Clinic, Barcelona, Spain., Bender B; Department of Diagnostic and Interventional Neuroradiology, University of Tübingen, Tübingen, Germany., Bernasconi N; Neuroimaging of Epilepsy Laboratory, Montreal Neurological Institute and Hospital, Mcgill University, Montreal, Quebec, Canada., Bernasconi A; Neuroimaging of Epilepsy Laboratory, Montreal Neurological Institute and Hospital, Mcgill University, Montreal, Quebec, Canada., Bernhardt BC; Neuroimaging of Epilepsy Laboratory, Montreal Neurological Institute and Hospital, Mcgill University, Montreal, Quebec, Canada.; Multimodal Imaging and Connectome Analysis Lab, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada., Blümcke I; Department of Neuropathology, University Hospital Erlangen, Germany., Carlson C; Comprehensive Epilepsy Center, Department of Neurology, New York University School of Medicine, New York, USA.; Medical College of Wisconsin, Department of Neurology, Milwaukee, WI, USA., Cavalleri GL; Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.; FutureNeuro Research Centre, RCSI, Dublin, Ireland., Cendes F; Department of Neurology, University of Campinas, Campinas, Brazil., Concha L; Instituto de Neurobiología, Universidad Nacional Autónoma de México. Querétaro, Querétaro, México., Delanty N; Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.; FutureNeuro Research Centre, RCSI, Dublin, Ireland.; Division of Neurology, Beaumont Hospital, Dublin 9, Ireland., Depondt C; Department of Neurology, Hôpital Erasme, Universite Libre de Bruxelles, Brussels 1070, Belgium., Devinsky O; Comprehensive Epilepsy Center, Department of Neurology, New York University School of Medicine, New York, USA., Doherty CP; FutureNeuro Research Centre, RCSI, Dublin, Ireland.; Neurology Department, St. James's Hospital, Dublin 8, Ireland., Focke NK; Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; Department of Clinical Neurophysiology, University Medicine Göttingen, Göttingen, Germany., Gambardella A; Institute of Molecular Bioimaging and Physiology of the National Research Council (IBFM-CNR), Catanzaro, Italy.; Institute of Neurology, University 'Magna Græcia', Catanzaro, Italy., Guerrini R; Pediatric Neurology Unit, Children's Hospital A. Meyer-University of Florence, Italy.; IRCCS Stella Maris Foundation, Pisa, Italy., Hamandi K; Institute of Psychological Medicine and Clinical Neurosciences, Hadyn Ellis Building, Maindy Road, Cardiff, UK.; Department of Neurology, University Hospital of Wales, Cardiff, UK., Jackson GD; The Florey Institute of Neuroscience and Mental Health, Austin Campus, Melbourne, VIC, Australia.; Florey Department of Neuroscience and Mental Health, The University of Melbourne, Melbourne, VIC, Australia., Kälviäinen R; Epilepsy Center, Department of Neurology, Kuopio University, Kuopio, Finland.; Institute of Clinical Medicine, Neurology, University of Eastern Finland, Kuopio, Finland., Kochunov P; Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Maryland, USA., Kwan P; Department of Neurology, Royal Melbourne Hospital, Parkville, 3050, Australia., Labate A; Institute of Molecular Bioimaging and Physiology of the National Research Council (IBFM-CNR), Catanzaro, Italy.; Institute of Neurology, University 'Magna Græcia', Catanzaro, Italy., McDonald CR; Multimodal Imaging Laboratory, University of California San Diego, San Diego, California, USA.; Department of Psychiatry, University of California San Diego, San Diego, California, USA., Meletti S; Department of Biomedical, Metabolic, and Neural Science, University of Modena and Reggio Emilia, NOCSE Hospital, Modena, Italy., O'Brien TJ; Department of Neurology, Royal Melbourne Hospital, Parkville, 3050, Australia.; Department of Medicine, University of Melbourne, Parkville, VIC, 3052, Australia., Ourselin S; Translational Imaging Group, Centre for Medical Image Computing, University College London, London, UK., Richardson MP; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.; Department of Neurology, King's College Hospital, London, UK., Striano P; Pediatric Neurology and Muscular Diseases Unit, Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genova, Italy., Thesen T; Comprehensive Epilepsy Center, Department of Neurology, New York University School of Medicine, New York, USA.; Department of Physiology, Neuroscience and Behavioral Science, St. George's University, Grenada, West Indies., Wiest R; Support Center for Advanced Neuroimaging (SCAN), University Institute for Diagnostic and Interventional Neuroradiology, Inselspital, University of Bern, Bern, Switzerland., Zhang J; Cognitive Science Department, Xiamen University, Xiamen, China.; Fujian Key Laboratory of the Brain-like Intelligent Systems, China., Vezzani A; Dept of Neuroscience, Mario Negri Institute for Pharmacological Research, Via G. La Masa 19, 20156 Milano, Italy., Ryten M; Reta Lila Weston Institute and Department of Molecular Neuroscience, UCL Institute of Neurology, London WC1N 3BG, UK.; Department of Medical and Molecular Genetics, King's College London, London SE1 9RT, UK., Thompson PM; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, California, USA., Sisodiya SM; Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, London, UK.; Chalfont Centre for Epilepsy, Bucks, UK.

Publikováno v: Brain : a journal of neurology [Brain] 2018 Feb 01; Vol. 141 (2), pp. 391-408.