Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Lohans Pedrera"'
Autor:
Carsten Berndt, Hamed Alborzinia, Vera Skafar Amen, Scott Ayton, Uladzimir Barayeu, Alexander Bartelt, Hülya Bayir, Christina M. Bebber, Kivanc Birsoy, Jan P. Böttcher, Simone Brabletz, Thomas Brabletz, Ashley R. Brown, Bernhard Brüne, Giorgia Bulli, Alix Bruneau, Quan Chen, Gina M. DeNicola, Tobias P. Dick, Ayelén Distéfano, Scott J. Dixon, Jan B. Engler, Julia Esser-von Bieren, Maria Fedorova, José Pedro Friedmann Angeli, Manuel A. Friese, Dominic C. Fuhrmann, Ana J. García-Sáez, Karolina Garbowicz, Magdalena Götz, Wei Gu, Linda Hammerich, Behrouz Hassannia, Xuejun Jiang, Aicha Jeridi, Yun Pyo Kang, Valerian E. Kagan, David B. Konrad, Stefan Kotschi, Peng Lei, Marlène Le Tertre, Sima Lev, Deguang Liang, Andreas Linkermann, Carolin Lohr, Svenja Lorenz, Tom Luedde, Axel Methner, Bernhard Michalke, Anna V. Milton, Junxia Min, Eikan Mishima, Sebastian Müller, Hozumi Motohashi, Martina U. Muckenthaler, Shohei Murakami, James A. Olzmann, Gabriela Pagnussat, Zijan Pan, Thales Papagiannakopoulos, Lohans Pedrera Puentes, Derek A. Pratt, Bettina Proneth, Lukas Ramsauer, Raphael Rodriguez, Yoshiro Saito, Felix Schmidt, Carina Schmitt, Almut Schulze, Annemarie Schwab, Anna Schwantes, Mariluz Soula, Benedikt Spitzlberger, Brent R. Stockwell, Leonie Thewes, Oliver Thorn-Seshold, Shinya Toyokuni, Wulf Tonnus, Andreas Trumpp, Peter Vandenabeele, Tom Vanden Berghe, Vivek Venkataramani, Felix C.E. Vogel, Silvia von Karstedt, Fudi Wang, Frank Westermann, Chantal Wientjens, Christoph Wilhelm, Michele Wölk, Katherine Wu, Xin Yang, Fan Yu, Yilong Zou, Marcus Conrad
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103211- (2024)
Ferroptosis is a pervasive non-apoptotic form of cell death highly relevant in various degenerative diseases and malignancies. The hallmark of ferroptosis is uncontrolled and overwhelming peroxidation of polyunsaturated fatty acids contained in membr
Externí odkaz:
https://doaj.org/article/704bf377a6004407992c3cd92011cf30
Autor:
Carlos Manuel Álvarez Valcárcel, Lohans Pedrera Puentes, Carmen Soto Febles, Javier Alvarado Mesén, Uris L. Ros Quincoces, María E. Lanio Ruíz, Aisel Valle Garay, María Laura Fanani, Fabiola Pazos Santos, Pedro Alberto Valiente Flores, Ana María Hernández Vázquez, Yadira de la Patria Hervis Valdés
Publikováno v:
Anales de la Academia de Ciencias de Cuba, Vol 12, Iss 2 (2022)
Introducción. Las actinoporinas (AP) son proteínas formadoras de poro (PFP) que se aso - cian a membranas conduciendo a la muerte celular. Sticholysinas I y II (St, StI/II) se encuen- tran entre las AP más potentes descritas en la naturaleza. El
Externí odkaz:
https://doaj.org/article/cf05863606c241fb820cf9d74bddd6ef
Autor:
Lohans Pedrera, Uris Ros, Maria Laura Fanani, María E. Lanio, Richard M. Epand, Ana J. García-Sáez, Carlos Álvarez
Publikováno v:
Toxins, Vol 15, Iss 1, p 80 (2023)
Actinoporins have emerged as archetypal α-pore-forming toxins (PFTs) that promote the formation of pores in membranes upon oligomerization and insertion of an α-helix pore-forming domain in the bilayer. These proteins have been used as active compo
Externí odkaz:
https://doaj.org/article/ff19e9367bf04d36ab79cb18104bfecc
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7, p 2412 (2020)
Pyroptosis, necroptosis, and ferroptosis are well-characterized forms of regulated necrosis that have been associated with human diseases. During regulated necrosis, plasma membrane damage facilitates the movement of ions and molecules across the bil
Externí odkaz:
https://doaj.org/article/a25d8f3de9184c8195b83d4d7741f608
Akademický článek
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Autor:
Aracelys López, Aisel Valle, Lohans Pedrera, Diana Martínez, Rafael Fando, Shirley Schreier, Carlos Álvarez, María E Lanio, Fabiola Pazos
Publikováno v:
Biotecnología Aplicada, Vol 28, Iss 1, Pp 13-18
The mechanism of pore formation by actinoporins is a multistep process, involving binding of water soluble monomer to membrane and subsequent oligomerization of monomers on the membrane surface, forming a functional pore. However, molecular details o
Externí odkaz:
https://doaj.org/article/027e0977d05445c59a8ad3de84afa1b6
Autor:
Javier Alvarado, Yeney Álvarez, Lohans Pedrera, Uris Ros, María E Lanio, Aisel Valle, Carlos Álvarez
Publikováno v:
Biotecnología Aplicada, Vol 31, Iss 1, Pp 53-56
Actinoporins are highly hemolytic pore-forming proteins with a molecular mass of around 20 kDa and high affinity for sphingomyelin-containing membranes. On the crude extract of the sea anemone Anthopleura nigrescens, hemolytic activity (HA) was detec
Externí odkaz:
https://doaj.org/article/5e312501bcbe4c8f8d19267939c4eb58
Autor:
Uris Ros, Lohans Pedrera, Diana Martínez, Mayra Tejuca, Fabiola Pazos, Maria E Lanio, Carlos Alvarez
Publikováno v:
Biotecnología Aplicada, Vol 30, Iss 4, Pp 312-316
The Caribbean Sea anemone Stichodactyla helianthus produces two pore-forming proteins, sticholysins I and II (StI and StII). To clarify the contribution of the first thirty (StII) or thirty-one (StI) N-terminal amino acid residues to the activity of
Externí odkaz:
https://doaj.org/article/9c06ca0999244b0c9626f6b2901bd8e0
Autor:
Uris Ros, Stephan Hailfinger, Jenny Stroh, Silvia von Karstedt, Rafael A. Espiritu, Lohans Pedrera, Josephine Weber, Anja Schmitt, Ana J. García-Sáez
Publikováno v:
Cell Death & Differentiation. 28:1644-1657
Ferroptosis is an iron-dependent form of regulated necrosis associated with lipid peroxidation. Despite its key role in the inflammatory outcome of ferroptosis, little is known about the molecular events leading to the disruption of the plasma membra
Publikováno v:
Current Opinion in Structural Biology
Pore-forming proteins (PFPs) are of special interest because of the association of their activity with the disruption of the membrane impermeability barrier and cell death. They generally convert from a monomeric, soluble form into transmembrane olig