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Intrinsically disordered region amplifies membrane remodeling to augment selective ER-phagy.

Autor: Poveda-Cuevas SA; Goethe University Frankfurt, School of Medicine, Institute of Biochemistry II, Frankfurt am Main 60590, Germany.; Goethe University Frankfurt, Buchmann Institute for Molecular Life Sciences, Riedberg Campus, Frankfurt am Main 60438, Germany., Lohachova K; Goethe University Frankfurt, School of Medicine, Institute of Biochemistry II, Frankfurt am Main 60590, Germany.; Goethe University Frankfurt, Buchmann Institute for Molecular Life Sciences, Riedberg Campus, Frankfurt am Main 60438, Germany., Markusic B; Goethe University Frankfurt, School of Medicine, Institute of Biochemistry II, Frankfurt am Main 60590, Germany.; International Max Planck Research School on Cellular Biophysics, Max-von-Laue-Strasse 3, Frankfurt am Main 60438, Germany., Dikic I; Goethe University Frankfurt, School of Medicine, Institute of Biochemistry II, Frankfurt am Main 60590, Germany.; Goethe University Frankfurt, Buchmann Institute for Molecular Life Sciences, Riedberg Campus, Frankfurt am Main 60438, Germany., Hummer G; Max-Planck Institute of Biophysics, Department of Theoretical Biophysics, Frankfurt am Main 60438, Germany.; Goethe University Frankfurt, Department of Physics, Institute of Biophysics, Frankfurt am Main 60438, Germany., Bhaskara RM; Goethe University Frankfurt, School of Medicine, Institute of Biochemistry II, Frankfurt am Main 60590, Germany.; Goethe University Frankfurt, Buchmann Institute for Molecular Life Sciences, Riedberg Campus, Frankfurt am Main 60438, Germany.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Oct 29; Vol. 121 (44), pp. e2408071121. Date of Electronic Publication: 2024 Oct 25.