Výsledky vyhledávání - "Logesh Dharmar"

Akademický článek

Distal spike initiation zone location estimation by morphological simulation of ionic current filtering demonstrated in a novel model of an identified Drosophila motoneuron.

Autor: Cengiz Günay, Fred H Sieling, Logesh Dharmar, Wei-Hsiang Lin, Verena Wolfram, Richard Marley, Richard A Baines, Astrid A Prinz

Publikováno v: PLoS Computational Biology, Vol 11, Iss 5, p e1004189 (2015)

Studying ion channel currents generated distally from the recording site is difficult because of artifacts caused by poor space clamp and membrane filtering. A computational model can quantify artifact parameters for correction by simulating the curr

Externí odkaz: https://doaj.org/article/902bec78164e493b87159bb8fbcf69a4

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Lack of utility of measuring serum bilirubin concentration in distinguishing perforation status of pediatric appendicitis

Autor: Santina Bruno, Peter Homel, David Attaway, William Bonadio, Logesh Dharmar, Derek Tam

Publikováno v: The American Journal of Emergency Medicine. 35:885-888

Background Pediatric appendicitis is a common, potentially serious condition. Determining perforation status is crucial to planning effective management. Purpose Determine the efficacy of serum total bilirubin concentration [STBC] in distinguishing p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e12277663cbbc80f8d0787baf14db7
https://doi.org/10.1016/j.ajem.2017.01.056

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A novel model of an identified Drosophila crawl motoneuron for investigating functional effects of ion channel type across larval developmental stages

Autor: Fred H. Sieling, Astrid A. Prinz, Logesh Dharmar, Cengiz Günay, Richard A. Baines

Publikováno v: BMC Neuroscience, Vol 12, Iss Suppl 1, p P258 (2011)
BMC Neuroscience
Europe PubMed Central

Drosophila is a powerful genetic model system for investigating neuronal function. Most of the important membrane ion channel genes, such as voltage-gated sodium and potassium channels, were first identified and isolated in the fruit fly. Technical a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb9774194d4de0e259543e41dc661971
https://doi.org/10.1186/1471-2202-12-s1-p258

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A compartmental model of an identified Drosophila larval motoneuron for investigating functional effects of ion channel parameters

Autor: Cengiz Günay, Astrid A. Prinz, Richard A. Baines, Logesh Dharmar, Fred H. Sieling

Publikováno v: BMC Neuroscience

Drosophila is a powerful genetic model system for investigating neuronal function. Several important membrane ion channel genes, such as voltage-gated sodium and potassium channels, were first identified and isolated in the fruit fly. Technical advan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f603ec2354816343b4b0d49d1440e2ed
http://europepmc.org/articles/PMC3403305

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Modeling Drosophila motoneurons to examine the functional effect of Na channel splice variants

Autor: Richard Marley, Fred H. Sieling, Astrid A. Prinz, Richard A. Baines, Logesh Dharmar, Wei-Hsiang Lin, Cengiz Günay

Publikováno v: BMC Neuroscience
Europe PubMed Central
BMC Neuroscience, Vol 11, Iss Suppl 1, p P147 (2010)

Neurons have diverse electrophysiological characteristics controlled by voltage-gated ion channels. It is not known how much of the diversity of neuronal activity is caused by differential channel gene expression as opposed to alternate splicing of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6851d59f1bcda02595bf06da0e7de032

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