Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Loganathan Palanikumar"'
Autor:
Sudhir Kumar Sharma, Loganathan Palanikumar, Renu Pasricha, Thirumurugan Prakasam, Mazin Magzoub, Ramesh Jagannathan
Publikováno v:
Pharmaceutics, Vol 16, Iss 11, p 1471 (2024)
Background/Objectives: The primary goal of our research is to develop a process to prepare an aqueous dispersion of Cisplatin, an important anticancer drug, with increased solubility and storage stability. Method: In this context, we report the use o
Externí odkaz:
https://doaj.org/article/e5a91634cce44c18b0130db59e558f0d
Autor:
Sudhir Kumar Sharma, Sumaya Al Hosani, Mona Kalmouni, Anjana Ramdas Nair, Loganathan Palanikumar, Renu Pasricha, Kirsten C. Sadler, Mazin Magzoub, Ramesh Jagannathan
Publikováno v:
ACS Omega, Vol 5, Iss 9, Pp 4558-4567 (2020)
Externí odkaz:
https://doaj.org/article/c7eaf05c39bb44bcab799d50b58a1acb
Akademický článek
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Autor:
Laura Karpauskaite, Ahmed J. Afzal, Ibrahim Chehade, Jemil Ahmed, Renu Pasricha, Mazin Magzoub, Andrew D. Hamilton, Debabrata Maity, Mona Kalmouni, Loganathan Palanikumar, Sunil Kumar, Maheen Alam, Tatiana Houhou, Gennaro Esposito, Zackary Falls, Shake Karapetyan, Yamanappa Hunashal, Ram Samudrala, Mohamed Al-Sayegh, Liaqat Ali, Sarah Hassan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-24 (2021)
Nature Communications
Nature Communications
Missense mutations in p53 are severely deleterious and occur in over 50% of all human cancers. The majority of these mutations are located in the inherently unstable DNA-binding domain (DBD), many of which destabilize the domain further and expose it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::914b9d23167b4db0a4609f8d776a3030
https://doaj.org/article/aabfbc8d47544f739652c54bd2eb3f1f
https://doaj.org/article/aabfbc8d47544f739652c54bd2eb3f1f
Publikováno v:
Biochemistry. 59:2259-2273
Cancer cells are often characterized by elevated levels of mitochondrion-bound hexokinase II (HKII), which facilitates their survival, proliferation, and metastasis. Here, we have designed a cancer-selective cell-penetrating peptide (CPP) by covalent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72350928acd31cf76a394d5a3e19b673
https://doi.org/10.1021/acs.biochem.0c00141
https://doi.org/10.1021/acs.biochem.0c00141
Autor:
Kirsten C. Sadler, Loganathan Palanikumar, Seema Sharma, Anjana Ramdas Nair, Sumaya Al Hosani, Ramesh Jagannathan, Mona Kalmouni, Mazin Magzoub, Renu Pasricha
Publikováno v:
ACS Omega, Vol 5, Iss 9, Pp 4558-4567 (2020)
Cisplatin is a highly toxic material used clinically as a potent chemotherapeutic. While effective against some cancers, toxicity limits widespread use and low solubility confounds delivery. To formulate a better tolerated and more water-soluble form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d2cbe9b7c0fc638d5bbaf51977c65c3
https://doaj.org/article/c7eaf05c39bb44bcab799d50b58a1acb
https://doaj.org/article/c7eaf05c39bb44bcab799d50b58a1acb
Autor:
Ja-Hyoung Ryu, Yao Lu, Eun Seong Choi, Wei Pang, Xuexin Duan, Loganathan Palanikumar, Yanyan Wang, Jurriaan Huskens
Publikováno v:
ACS Applied Materials and Interfaces, 11(22), 19734-19742. American Chemical Society
The intracellular delivery efficiency of drug-loaded nanocarriers is often limited by biological barriers arising from the plasma membrane and the cell interior. In this work, the entering of doxorubicin (Dox)-loaded mesoporous silica nanoparticles (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31fa70e9df0049a41d605b818949bf8a
https://doi.org/10.1021/acsami.9b02447
https://doi.org/10.1021/acsami.9b02447
Autor:
Yujie Ye, Mazin Magzoub, Loganathan Palanikumar, Francisco N. Barrera, Daiane S. Alves, Stephen J. Kennel, Vanessa P. Nguyen, Jonathan S. Wall
Publikováno v:
Journal of Controlled Release. 298:142-153
pH-responsive peptides are promising therapeutic molecules that can specifically target the plasma membrane in the acidified extracellular medium that bathes cells in tumors. We designed the a cidity- t riggered ra tional m embrane (ATRAM) peptide to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be48050aedbc5a2d9e73e4df5b5d009
https://doi.org/10.1016/j.jconrel.2019.02.010
https://doi.org/10.1016/j.jconrel.2019.02.010
Autor:
Mazin Magzoub, Sarah Hassan, Maheen Alam, Yamanappa Hunashal, Gennaro Esposito, Mohamed Al-Sayegh, Ibrahim Chehade, Liaqat Ali, Zackary Falls, Andrew D. Hamilton, Renu Pasricha, Sunil Kumar, Laura Karpauskaite, Ahmed J. Afzal, Mona Kalmouni, Jemil Ahmed, Ram Samudrala, Debabrata Maity, Loganathan Palanikumar, Shake Karapetyan
Missense mutations in p53 are severely deleterious and occur in over 50% of all human cancers. The vast majority of these mutations are located in the inherently unstable DNA-binding domain (DBD), many of which destabilize the domain further and expo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fa961805711ad26790abd3b96f53b97
https://doi.org/10.1101/2020.08.10.243154
https://doi.org/10.1101/2020.08.10.243154
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.