Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Logan Zhan"'
Autor:
Nannan Li, Yibo Yin, Jesse Rodriguez, Meghan Logun, Logan Zhan, Jiasi Zhang, Zev A Binder, Zhiguo Lin
Publikováno v:
Neuro-Oncology. 24:vii214-vii214
Chimeric antigen receptor (CAR)-T cells have had a significant effect in hematological diseases, with a recent study confirming that the cells can last for ten years in vivo. Unfortunately, to date, CAR-T cells have had little effect in solid tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69e801d56f213b98749f948bcc39f944
https://doi.org/10.1093/neuonc/noac209.822
https://doi.org/10.1093/neuonc/noac209.822
Autor:
Tyler E Papp, Hamideh Parhiz, Jesse L Rodriguez, Logan Zhang, Kelly A Hicks, Zev Binder, Donald O’Rourke
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/2d37bd4b9a77484da10245646021105e
Autor:
Edward Z. Song, Xin Wang, Benjamin I. Philipson, Qian Zhang, Radhika Thokala, Logan Zhang, Charles-Antoine Assenmacher, Zev A. Binder, Guo-li Ming, Donald M. O’Rourke, Hongjun Song, Michael C. Milone
Publikováno v:
Molecular Therapy: Oncolytics, Vol 27, Iss , Pp 288-304 (2022)
Antigen heterogeneity that results in tumor antigenic escape is one of the major obstacles to successful chimeric antigen receptor (CAR) T cell therapies in solid tumors including glioblastoma multiforme (GBM). To address this issue and improve the e
Externí odkaz:
https://doaj.org/article/52ea338bdced4e4cb747e87c08377ff4
Autor:
Radhika Thokala, Zev A. Binder, Yibo Yin, Logan Zhang, Jiasi Vicky Zhang, Daniel Y. Zhang, Michael C. Milone, Guo-li Ming, Hongjun Song, Donald M. O’Rourke
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Tumor heterogeneity is a key reason for therapeutic failure and tumor recurrence in glioblastoma (GBM). Our chimeric antigen receptor (CAR) T cell (2173 CAR T cells) clinical trial (NCT02209376) against epidermal growth factor receptor (EGFR) variant
Externí odkaz:
https://doaj.org/article/9376febd32b248639a21b169cbce0d47
Autor:
Angela N. Viaene, Bo Zhang, Maria Martinez-Lage, Chaomei Xiang, Umberto Tosi, Jayesh P. Thawani, Busra Gungor, Yuankun Zhu, Laura Roccograndi, Logan Zhang, Robert L. Bailey, Phillip B. Storm, Donald M. O’Rourke, Adam C. Resnick, M. Sean Grady, Nadia Dahmane
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Meningiomas are the most common primary brain tumor of adults. The majority are benign (WHO grade I), with a mostly indolent course; 20% of them (WHO grade II and III) are, however, considered aggressive and require a more complex management
Externí odkaz:
https://doaj.org/article/fa69460c81d74426a99adcea5c366475
Autor:
Yibo Yin, Alina C. Boesteanu, Zev A. Binder, Chong Xu, Reiss A. Reid, Jesse L. Rodriguez, Danielle R. Cook, Radhika Thokala, Kristin Blouch, Bevin McGettigan-Croce, Logan Zhang, Christoph Konradt, Alexandria P. Cogdill, M. Kazim Panjwani, Shuguang Jiang, Denis Migliorini, Nadia Dahmane, Avery D. Posey, Jr., Carl H. June, Nicola J. Mason, Zhiguo Lin, Donald M. O’Rourke, Laura A. Johnson
Publikováno v:
Molecular Therapy: Oncolytics, Vol 11, Iss , Pp 20-38 (2018)
We generated two humanized interleukin-13 receptor α2 (IL-13Rα2) chimeric antigen receptors (CARs), Hu07BBz and Hu08BBz, that recognized human IL-13Rα2, but not IL-13Rα1. Hu08BBz also recognized canine IL-13Rα2. Both of these CAR T cell construc
Externí odkaz:
https://doaj.org/article/c4f59e6339ce4efa84b3ecf00abab181