Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Logan Spaller"'
Publikováno v:
Curr Opin Struct Biol
The majority of regulated protein degradation in eukaryotes is accomplished by the 26S proteasome, the large proteolytic complex responsible for removing regulatory proteins and damaged proteins. Proteins are targeted to the proteasome by ubiquitinat
Autor:
Peggy Hsieh, Logan Spaller, Keith Weninger, Dan Burke, Austin E. Smith, Dorothy A. Erie, Zimeng M. Li, Bangchen Wang, Pengyu Hao, Kira C. Bradford, Hunter Wilkins, Edward Chan, Dong Wu, Chunwei Du, Jacob Gauer
Publikováno v:
Proc Natl Acad Sci U S A
DNA mismatch repair (MMR) corrects errors that occur during DNA replication. In humans, mutations in the proteins MutSα and MutLα that initiate MMR cause Lynch syndrome, the most common hereditary cancer. MutSα surveilles the DNA, and upon recogni
Publikováno v:
The Journal of Membrane Biology. 246:257-262
Understanding the mechanisms of antimicrobial, cytolytic and cell-penetrating peptides is important for the design of new peptides to be used as cargo-delivery systems or antimicrobials. But these peptides should not be hemolytic. Recently, we design
Autor:
Francis Dean O. Ablan, Julie M. Trieu, Paulo F. Almeida, B. Logan Spaller, Sterling A. Wheaten
Publikováno v:
Journal of the American Chemical Society. 135(44)
The ability of amphipathic polypeptides with substantial net positive charges to translocate across lipid membranes is a fundamental problem in physical biochemistry. These peptides should not passively cross the bilayer nonpolar region, but they do.
Autor:
Wheaten, Sterling A., Ablan, Francis D. O., Logan Spaller, B., Trieu, Julie M., Almeida, Paulo F.
Publikováno v:
Journal of the American Chemical Society; 11/6/2013, Vol. 135 Issue 44, p16517-16525, 9p
Publikováno v:
Biophysical Journal. (2):293a
The ability of amphipathic polypeptides with substantial net positive charges to translocate across lipid membranes is a fundamental problem in physical biochemistry. These peptides should not passively cross the bilayer nonpolar region, but they do.