Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Logan Slade"'
Autor:
Dipsikha Biswas, Logan Slade, Luke Duffley, Neil Mueller, Khoi Thien Dao, Angella Mercer, Shanmugasundaram Pakkiriswami, Yassine El Hiani, Petra C. Kienesberger, Thomas Pulinilkunnil
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-12 (2021)
Proposed mechanism. A Doxorubicin (DOX) targets the BCAA catabolic pathway in TNBCs, by downregulating BCKDK and augmenting clearance of intracellular BCKAs. B Genetic or pharmacological (high BT2 concentration) inhibition of BCKDK results in increas
Externí odkaz:
https://doaj.org/article/004b3d68105a445d9f322e3d584c6ae8
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Central Nervous System Pharmacology - Neuropharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1cbdeafdfbb2b8a010f659de1ac8522
https://doi.org/10.1124/jpet.122.184440
https://doi.org/10.1124/jpet.122.184440
Publikováno v:
The Journal of biological chemistry. 298(12)
Triple-negative breast cancer (TNBC) poses significant challenges for treatment given the lack of targeted therapies and increased probability of relapse. It is pertinent to identify vulnerabilities in TNBC and develop newer treatments. Our prior res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c6219aedfeef396719d8fa6b60aac3
https://pubmed.ncbi.nlm.nih.gov/36372230
https://pubmed.ncbi.nlm.nih.gov/36372230
Autor:
Mahmoud Abdellatif, Nuzhat Ahsan, Amelina Albornoz, Yahyah Aman, Allen Andres, Catherine Arden, Daniel Asa, Belén Bellido, Sihem Boudina, Alfredo Briones-Herrera, Mauricio Budini, Elizabeth Bueno, Olivier Camuzard, Georges F. Carle, Santosh Chauhan, Ramon Corbalan, Alfredo Criollo, Srinivasulu Dasanna, Guido R.Y. De Meyer, Abhinav Diwan, Maria Jose Donate-Lagartos, Robyn Duttenhefner, Tobias Eisenberg, Evandro F. Fang, Johannes Frank, Valeria Garrido-Moreno, Luis Garrido-Olivares, Merilin Georgiou, Saurav Ghimire, Tania Gómez-Sierra, Ruben Gudmundsrud, Andreas Guenther, Pieter-Jan Guns, Congcong He, G. Vignir Helgason, Nina Hermans, Sergio Hernandez-Diaz, Angela Ianniciello, Moydul Islam, Kautilya Kumar Jena, Hiroshi Katsuki, Martina Korfei, Viktor I. Korolchuk, Nicholas T. Ktistakis, Sergio Lavandero, Mark Li, Senka Ljubojević-Holzer, Poornima Mahavadi, Patrick Main, Maria Manifava, Greg R. Markby, Wim Martinet, Elena Martínez-Klimova, Subhash Mehto, Jason C. Mills, Cédric HG. Neutel, Ngoc Uyen Nhi Nguyen, José Pedraza-Chaverri, Daniel Peña-Oyarzún, Valérie Pierrefite-Carle, Felipe X. Pimentel-Muiños, Thomas Pulinilkunnil, Yoana Rabanal-Ruiz, Megan D. Radyk, Christian Rodríguez, Lynn Roth, Beverly A. Rothermel, Kei Sakamoto, Irene Sanchez-Mirasierra, Simon Sedej, Takahiro Seki, Alvaro Sequeida, Liu Shi, Sangita C. Sinha, Logan Slade, Sandra-Fausia Soukup, Lillian B. Spatz, Bieke Steenput, Takayuki Tatsumi, Kateřina Čechová, Marie-Charlotte Trojani, Satoshi Tsukamoto, Silvia Vega-Rubín-de-Celis, Vishaka Vinod, Martin Vyhnalek, Amelia Williams, Samuel Wyatt, Chenglong Xie, Ling Yang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9b7da36fa6e070b2f6b58871b491c5f
https://doi.org/10.1016/b978-0-12-822003-0.01002-0
https://doi.org/10.1016/b978-0-12-822003-0.01002-0
Autor:
Logan Slade, Thomas Pulinilkunnil
Publikováno v:
Autophagy in Health and Disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c2b7619a8a2ed8af8eb0208b03604a5
https://doi.org/10.1016/b978-0-12-822003-0.00005-x
https://doi.org/10.1016/b978-0-12-822003-0.00005-x
Autor:
Angella Mercer, Shanmugasundaram Pakkiriswami, Neil Mueller, Dipsikha Biswas, Thomas Pulinilkunnil, Yassine El-Hiani, Luke Duffley, Khoi Thien Dao, Logan Slade, Petra Kieneseberger
Triple-negative breast cancers (TNBCs) are characterized by poor survival, prognosis and gradual resistance to cytotoxic chemotherapeutics, like doxorubicin (DOX), which is limited by its cardiotoxic and chemoresistant effects that manifest over time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afb3f117be864fa346e17cc2ebef635b
https://doi.org/10.1101/2021.05.18.444634
https://doi.org/10.1101/2021.05.18.444634
Autor:
Daniel Fuller, Emily Colwell, Jonathan Low, Kassia Orychock, Melissa Ann Tobin, Bo Simango, Richard Buote, Desiree Van Heerden, Hui Luan, Kimberley Cullen, Logan Slade, Nathan G A Taylor
BACKGROUND Consumer-wearable activity trackers are small electronic devices that record fitness and health-related measures. OBJECTIVE The purpose of this systematic review was to examine the validity and reliability of commercial wearables in measur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81fe0f1bdc019d77ca0cc14d2ab70018
https://doi.org/10.2196/preprints.18694
https://doi.org/10.2196/preprints.18694
Autor:
Nathan G. A. Taylor, Logan Slade, Kimberley Cullen, Jonathan LeRon Low, Desiree Van Heerden, Emily Colwell, Richard Buote, Melissa Tobin, Hui Luan, Bo Simango, Kassia Orychock, Daniel Fuller
Publikováno v:
JMIR mHealth and uHealth
JMIR mHealth and uHealth, Vol 8, Iss 9, p e18694 (2020)
JMIR mHealth and uHealth, Vol 8, Iss 9, p e18694 (2020)
Background Consumer-wearable activity trackers are small electronic devices that record fitness and health-related measures. Objective The purpose of this systematic review was to examine the validity and reliability of commercial wearables in measur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a93bb11053baf1686fdf3ea24551cb77
https://pubmed.ncbi.nlm.nih.gov/32897239
https://pubmed.ncbi.nlm.nih.gov/32897239
Autor:
Marc E. Surette, Bahira Hussein, Thomas Pulinilkunnil, Purvi C. Trivedi, Stephane Flibotte, Logan Slade, Petra C. Kienesberger, Angella Mercer, Brian Rodrigues, Andrea Ballabio, Jordan J. Bartlett
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease. 1866(10)
Glucolipotoxicity following nutrient overload causes cardiomyocyte injury by inhibiting TFEB and suppressing lysosomal function. We ascertained whether in addition to the amount, the type of fatty acids (FAs) and duration of FA exposure regulate TFEB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4254c6cc23ba3571705254f94d1e02c7
https://pubmed.ncbi.nlm.nih.gov/32437957
https://pubmed.ncbi.nlm.nih.gov/32437957
Autor:
Dipsikha Biswas, Thomas Pulinilkunnil, Francis Ihionu, Yassine El Hiani, Logan Slade, Petra C. Kienesberger
Publikováno v:
The Biochemical journal. 477(1)
Transcription factor EB (TFEB) is a master regulator of lysosomal biogenesis and autophagy with critical roles in several cancers. Lysosomal autophagy promotes cancer survival through the degradation of toxic molecules and the maintenance of adequate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49c46825b0bdce7d97a35a72957d553d
https://pubmed.ncbi.nlm.nih.gov/31820786
https://pubmed.ncbi.nlm.nih.gov/31820786