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pro vyhledávání: '"Logan Richards"'
Publikováno v:
Genes, Vol 13, Iss 3, p 550 (2022)
Successful duplication of the genome requires the accurate replication of billions of base pairs of DNA within a relatively short time frame. Failure to accurately replicate the genome results in genomic instability and a host of diseases. To faithfu
Externí odkaz:
https://doaj.org/article/9a54b06724f141d1857d729db1eb86f5
Publikováno v:
Cell Reports. 41:111590
SUMMARYThe origin recognition complex (ORC) binds throughout the genome to initiate DNA replication. In metazoans, it is still unclear how ORC is targeted to specific loci to facilitate helicase loading and replication initiation. Here, we performed