Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Logan K. Laubach"'
Autor:
Ryan N. Porell, Julianna L. Follmar, Sean C. Purcell, Bryce Timm, Logan K. Laubach, David Kozirovskiy, Bryan E. Thacker, Charles A. Glass, Philip L. S. M. Gordts, Kamil Godula
Publikováno v:
ACS Chemical Biology. 17:1534-1542
Glycosaminoglycans (GAGs) are a class of highly negatively charged membrane-associated and extracellular matrix polysaccharides involved in the regulation of myriad biological functions, including cell adhesion, migration, signaling, and differentiat
Publikováno v:
European Journal of Orthopaedic Surgery & Traumatology.
Autor:
Ryan N. Porell, Julianna L. Follmar, Sean C. Purcell, Bryce Timm, Logan K. Laubach, David Kozirovskiy, Bryan E. Thacker, Charles A. Glass, Philip L. S. M. Gordts, Kamil Godula
Glycosaminoglycans (GAGs) are a class of highly negatively charged membrane associated and extracellular matrix polysaccharides involved in the regulation of myriad biological functions, including cell adhesion, migration, signaling and differentiati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c947296402bee27740e2f4a9cd7f0ed6
https://doi.org/10.1101/2022.03.04.482917
https://doi.org/10.1101/2022.03.04.482917
Publikováno v:
Biomater Sci
Biomaterials science, vol 9, iss 5
Biomaterials science, vol 9, iss 5
Growth factor (GF) patterning in stem cell spheroids, such as embryoid bodies (EBs), has been sought to guide their differentiation and organization into functional 3D tissue models and organoids. Current approaches relying on exposure of EBs to grad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a71ee71b71f084528f4098691e098c5
https://europepmc.org/articles/PMC7970653/
https://europepmc.org/articles/PMC7970653/
Autor:
Ryan N. Porell, Sandra L Leibel, Jonathan L. Torres, Chelsea D. Painter, Aaron F. Carlin, Aaron F. Garretson, Gregory J. Golden, Elizabeth M. Kwong, Rachael N. McVicar, Timothy M. Caradonna, Philip L.S.M. Gordts, Andrew B. Ward, Sumit K. Chanda, Daniel R. Sandoval, Zhang Yang, Benjamin P. Kellman, Blake M. Hauser, Charles A. Glass, Jessica Pihl, Kevin D. Corbett, Joyce Jose, Cameron Martino, Sydney A. Majowicz, Jeffrey D. Esko, Charlotte B Spliid, Xin Yin, Bryan E. Thacker, Aaron G. Schmidt, Anoop Narayanan, Kamil Godula, Hailee R. Perrett, Jared Feldman, Logan K. Laubach, Phillip L. Bartels, Thomas Mandel Clausen, Yuan Pu
Publikováno v:
Cell, vol 183, iss 4
Cell
Cell
We show that SARS-CoV-2 spike protein interacts with both cellular heparan sulfate and angiotensin-converting enzyme 2 (ACE2) through its receptor-binding domain (RBD). Docking studies suggest a heparin/heparan sulfate-binding site adjacent to the AC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a75e2afde17a8be9e8115c9a6dd2ee6
https://escholarship.org/uc/item/232927v1
https://escholarship.org/uc/item/232927v1
Cell surface engineering with synthetic glycomimetic co-receptors for FGF2 was used to establish gradients of stem cells with enhanced FGF2 affinity in embryoid bodies (EBs). Gradient shape was controlled by pre-assembly of glycomimetics into nanosca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03785ceab5b38f4ab195a423fd327428
https://doi.org/10.26434/chemrxiv.12755849.v1
https://doi.org/10.26434/chemrxiv.12755849.v1
Autor:
Aaron G. Schmidt, Gordts, Plsm, Chanda, S. K., Cameron Martino, Blake M. Hauser, Thomas Mandel Clausen, Yuan Pu, Sydney A. Majowicz, Rachael N. McVicar, Charlotte B Spliid, Sandra L Leibel, Xin Yin, Daniel R. Sandoval, Jonathan L. Torres, Benjamin P. Kellman, Timothy M. Caradonna, E. M. Kwong, Ryan N. Porell, Kamil Godula, Charles A. Glass, Aaron F. Carlin, Bryan E. Thacker, Jessica Pihl, Kevin D. Corbett, Andrew B. Ward, Jared Feldman, Hailee R. Perrett, Jeffrey D. Esko, Logan K. Laubach, Chelsea D. Painter, Anoop Narayanan, Phillip L. Bartels, Aaron F. Garretson, Gregory J. Golden, Joyce Jose, Zhang Yang
Publikováno v:
bioRxiv
We show that SARS-CoV-2 spike protein interacts with cell surface heparan sulfate and angiotensin converting enzyme 2 (ACE2) through its Receptor Binding Domain. Docking studies suggest a putative heparin/heparan sulfate-binding site adjacent to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71a9950cb2eacc5605613b031b210508
https://europepmc.org/articles/PMC7373134/
https://europepmc.org/articles/PMC7373134/
Autor:
Logan K. Laubach, Mia L. Huang, Kamil Godula, Ember M. Tota, Matthew R. Naticchia, Taryn M. Lucas
Publikováno v:
ACS Chemical Biology. 13:2880-2887
Cell surface glycans, such as heparan sulfate (HS), are increasingly identified as co-regulators of growth factor signaling in early embryonic development; therefore, chemical tailoring of HS activity within the cellular glycocalyx of stem cells offe