HIF1α-regulated glycolysis promotes activation-induced cell death and IFN-γ induction in hypoxic T cells

Autor: Hongxing Shen, Oluwagbemiga A. Ojo, Haitao Ding, Logan J. Mullen, Chuan Xing, M. Iqbal Hossain, Abdelrahman Yassin, Vivian Y. Shi, Zach Lewis, Ewa Podgorska, Shaida A. Andrabi, Maciek R. Antoniewicz, James A. Bonner, Lewis Zhichang Shi

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)

Abstract Hypoxia is a common feature in various pathophysiological contexts, including tumor microenvironment, and IFN-γ is instrumental for anti-tumor immunity. HIF1α has long been known as a primary regulator of cellular adaptive responses to hyp

Externí odkaz: https://doaj.org/article/17a66108966a4d25bc8186281738e71b

Phylogeny and evolution of large body size in the rove beetle genus Phlaeopterus Motschulsky, 1853 (Coleoptera: Staphylinidae: Omaliinae: Anthophagini)

Autor: Logan J. Mullen, Derek S. Sikes

Publikováno v: Arthropod Systematics & Phylogeny, Vol 79, Iss, Pp 75-98 (2021)
Arthropod Systematics & Phylogeny 79: 75-98

Abstract The omaliine rove beetle genus Phlaeopterus Motschulsky, 1853 contains 22 species. The genus is distributed across northwestern North America and eastern Asia. These beetles occur primarily along the edges of alpine snowfields and streams, h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b013b679040213e7ffc608032142e3bd
https://zenodo.org/record/4777521

The value of museums in the production, sharing, and use of entomological data to document hyperdiversity of the changing North

Autor: Derek S. Sikes, Jill Stockbridge, Matthew L. Bowser, Sarah Meierotto, Jozef Slowik, Toke T. Høye, Logan J. Mullen, Kathryn M. Daly

Publikováno v: Sikes, D S, Bowser, M, Daly, K, Høye, T T, Meierotto, S, Mullen, L, Slowik, J & Stockbridge, J 2017, ' The value of museums in the production, sharing, and use of entomological data to document hyperdiversity of the changing North ', Arctic Science, vol. 3, pp. 498-514 . https://doi.org/10.1139/as-2016-0038
Arctic Science, Vol 3, Iss 3, Pp 498-514 (2017)

If the current rate of climate change continues, the composition, distribution, and relative population sizes of species in the higher latitudes of the Northern Hemisphere are likely to change considerably. Understanding the magnitude of this change

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::697922614d0458fb1b742263804821da
https://pure.au.dk/ws/files/136274922/as_2016_0038.pdf