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pro vyhledávání: '"Logan Huff"'
Publikováno v:
The Journal of Immunology. 196:214.13-214.13
Despite a few very exciting results from adoptive cell transfer (ACT) therapy-based clinical trials, most studies have infused less than ideal cell populations into patients. Human CD4+ T cells differentiate into multiple effector subsets, but their
Publikováno v:
The Journal of Immunology. 192:71.26-71.26
Human CD4+ T cells differentiate into multiple effector subsets, but their distinct roles in anti-tumor immunity remain elusive. CD4+ T cell subsets enriched from bulk human CD4+ T cells [Th1 (CXCR3+), Th2 (CCR4+), and Th17 (CCR6+ or CD26hi)] were st
Publikováno v:
The Journal of Immunology. 190:170.26-170.26
Human CD4+ T cells can differentiate into multiple effector subsets, but their role in anti-tumor immunity remains incompletely elucidated. Further, the costimulatory molecules that effectively bolster their antitumor activity are unknown. To uncover
Publikováno v:
The Journal of Immunology. 188:46.29-46.29
TH17 cells play an essential role in regulating host defense and exacerbating various autoimmune diseases, but their role in tumor immunity remains incompletely elucidated. We found that CD28 abrogates TH17 expansion and function, while the inducible