Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Logan Hansen"'
Autor:
Jerome Campbell, Seth Springer, Karissa Finke, Dimitrios Fotiadis, Arik A. Zur, Colton Hall, Andrew Flint, Nathan Heeren, Avner Schlessinger, Brooklynn Venteicher, Allen A. Thomas, Kathleen M. Giacomini, Logan Hansen, Justine Bauer, Abby Anthony, Claire Colas, Evan Augustyn, Christopher Hernandez, Huan-Chieh Chien, Laura Stoner
Publikováno v:
Journal of medicinal chemistry, vol 61, iss 16
The L-type amino acid transporter 1 (LAT1, SLC7A5) transports essential amino acids across the blood—brain barrier (BBB) and into cancer cells. To utilize LAT1 for drug delivery, potent amino acid promoieties are desired, as prodrugs must compete w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2a392ee60913bced47e4a46046f4e08
https://doi.org/10.1021/acs.jmedchem.8b01007
https://doi.org/10.1021/acs.jmedchem.8b01007
Autor:
Yang Zhang, Jingxi Pan, Clint Piper, Liu Liu, Jeffrey J. Czajka, Tomasz Cierpicki, Mi Wang, Ming Lei, Naureen Aslam Khattak, Xiaoqiang Huang, Felicia Gray, Krishnapriya Chinnaswamy, Christoph H. Borchers, Logan Hansen, Jarrett S. Johnson, Jeanne A. Stuckey, Bingbing Wan, Pralay Mitra, David Shultis, Shaomeng Wang
One obstacle in de novo protein design is the vast sequence space that needs to be searched through to obtain functional proteins. We developed a new method using structural profiles created from evolutionarily related proteins to constrain the simul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2049c28c9ebb76d0727bc1ed758f0b38
https://europepmc.org/articles/PMC6876990/
https://europepmc.org/articles/PMC6876990/
Autor:
Kathleen M. Giacomini, Evan Augustyn, Claire Colas, Huan-Chieh Chien, Lawrence Lin, Christopher Hernandez, Arik A. Zur, Andrew Flint, Avner Schlessinger, Allen A. Thomas, Nathan Heeren, Logan Hansen, Sydney Miller, Karissa Finke
Publikováno v:
Bioorganic & medicinal chemistry letters, vol 26, iss 20
Zur, AA; Chien, HC; Augustyn, E; Flint, A; Heeren, N; Finke, K; et al.(2016). LAT1 activity of carboxylic acid bioisosteres: Evaluation of hydroxamic acids as substrates. Bioorganic and Medicinal Chemistry Letters, 26(20), 5000-5006. doi: 10.1016/j.bmcl.2016.09.001. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/7cq4q8r0
Zur, AA; Chien, HC; Augustyn, E; Flint, A; Heeren, N; Finke, K; et al.(2016). LAT1 activity of carboxylic acid bioisosteres: Evaluation of hydroxamic acids as substrates. Bioorganic and Medicinal Chemistry Letters, 26(20), 5000-5006. doi: 10.1016/j.bmcl.2016.09.001. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/7cq4q8r0
© 2016 Elsevier Ltd Large neutral amino acid transporter 1 (LAT1) is a solute carrier protein located primarily in the blood–brain barrier (BBB) that offers the potential to deliver drugs to the brain. It is also up-regulated in cancer cells, as p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f79fc9f89751545acb36c78b1f72fb97
https://escholarship.org/uc/item/7cq4q8r0
https://escholarship.org/uc/item/7cq4q8r0
Autor:
Arik A. Zur, Claire Colas, Kathleen M. Giacomini, Huan-Chieh Chien, Evan Augustyn, Allen A. Thomas, Logan Hansen, Karissa Finke, Nathan Heeren, Avner Schlessinger, Lawrence Lin
Publikováno v:
Augustyn, E; Finke, K; Zur, AA; Hansen, L; Heeren, N; Chien, HC; et al.(2016). LAT-1 activity of meta-substituted phenylalanine and tyrosine analogs. Bioorganic and Medicinal Chemistry Letters, 26(11), 2616-2621. doi: 10.1016/j.bmcl.2016.04.023. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/87g0x645
Bioorganic & medicinal chemistry letters, vol 26, iss 11
Bioorganic & medicinal chemistry letters, vol 26, iss 11
© 2016 Elsevier Ltd. All rights reserved. The transporter protein Large-neutral Amino Acid Transporter 1 (LAT-1, SLC7A5) is responsible for transporting amino acids such as tyrosine and phenylalanine as well as thyroid hormones, and it has been expl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07007467b3c500f14a6c86b2a7791b56
https://pubmed.ncbi.nlm.nih.gov/27106710
https://pubmed.ncbi.nlm.nih.gov/27106710
Autor:
Alfred B. Cunningham, Konstantin R. Romanenko, Sarah L. Codd, Joseph D. Seymour, Sarah J. Vogt, James E. Maneval, Logan Hansen, Jennifer A. Hornemann, Adrienne J. Phillips
Publikováno v:
Organic Geochemistry. 42:965-971
Recently 2D nuclear magnetic resonance (NMR) relaxation techniques have been able to access changes in pore structures through surface and diffusion based relaxation measurements. This research investigates the applicability of these methods for meas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93cc12a45e2eeb7e1ba9e72f710c3120
https://doi.org/10.1016/j.orggeochem.2011.03.014
https://doi.org/10.1016/j.orggeochem.2011.03.014