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pro vyhledávání: '"Logan G. Kavanaugh"'
The Resistance-Nodulation-Division (RND) efflux pump superfamily is pervasive among Gram-negative pathogens and contributes extensively to clinical antibiotic resistance. The opportunistic pathogenPseudomonas aeruginosacontains 12 RND-type efflux sys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a3d441cb7f55b63210857a69ac6b025
https://doi.org/10.1101/2023.03.24.533986
https://doi.org/10.1101/2023.03.24.533986
Autor:
Julio C. Ayala, William M. Shafer, Timothy D. Read, Richard G. Brennan, Maria A. Schumacher, Grace A. Beggs, Logan G Kavanaugh, Grace M Hooks
Publikováno v:
Nucleic Acids Research
Mutations within the mtrR gene are commonly found amongst multidrug resistant clinical isolates of Neisseria gonorrhoeae, which has been labelled a superbug by the Centers for Disease Control and Prevention. These mutations appear to contribute to an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a2c97055c04b00c1756472fe998a00e
https://doi.org/10.1093/nar/gkab213
https://doi.org/10.1093/nar/gkab213
Publikováno v:
Antimicrob Agents Chemother
Antibiotic collateral sensitivity, in which acquired resistance to one drug leads to decreased resistance to a different drug, occurs in Burkholderia multivorans . Here, we observed that treatment of extensively drug-resistant variants from a cystic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f4cc3fb06b99e0de0e841c89a47229
https://pubmed.ncbi.nlm.nih.gov/34097494
https://pubmed.ncbi.nlm.nih.gov/34097494
Publikováno v:
Int J Antimicrob Agents
Antibiotic collateral sensitivity (CS) occurs when a bacterium that acquires resistance to a treatment drug exhibits decreased resistance to a different drug. Here we identify reciprocal CS networks and candidate genes in Burkholderia multivorans. B.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43cbac025067f06178fbc54a40de0da7
https://pubmed.ncbi.nlm.nih.gov/32335276
https://pubmed.ncbi.nlm.nih.gov/32335276
Publikováno v:
Microb Drug Resist
Burkholderia multivorans is a member of the Burkholderia cepacia complex whose members are inherently resistant to many antibiotics and can cause chronic lung infections in patients with cystic fibrosis. A possible treatment for chronic infections ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0fafc1e9d4f92955dccb05cbf8679df
https://europepmc.org/articles/PMC6978779/
https://europepmc.org/articles/PMC6978779/