Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Loeser Eric M"'
Publikováno v:
Tetrahedron Letters. 57:1338-1341
We report an asymmetric synthesis of rosuvastatin starting from an α,β-unsaturated aldehyde precursor containing the rosuvastatin heterocyclic core at its terminus. The α,β-unsaturated carbonyl starting material was used in a highly stereoselecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2768468bd2688fc7ae48c481f53095a8
https://doi.org/10.1016/j.tetlet.2016.02.037
https://doi.org/10.1016/j.tetlet.2016.02.037
Publikováno v:
In Tetrahedron Letters 23 March 2016 57(12):1338-1341
Autor:
Stanislaw Babiak, Loeser Eric M
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 36:1959-1975
The effect of temperature on RP-LC retention of s-triazine derivatives containing amino amide substituents was studied. The slope of van't Hoff plots (ln(k′) vs 1/T) became less positive as the hydrophobicity of the amino amide R-groups increased.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cda371e38f3ac2d61f9da90ee855e7d
https://doi.org/10.1080/10826076.2012.704615
https://doi.org/10.1080/10826076.2012.704615
Publikováno v:
Drug Development and Industrial Pharmacy. 38:357-364
In this study, the tromethamine salt of an active pharmaceutical ingredient containing both a carboxylic acid and ethyl ester functionality was subjected to forced degradation conditions. Based on HPLC-MS analysis, it was found that tromethamine form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c34d48bf2b341c8017b97cc3b2536eba
https://doi.org/10.3109/03639045.2011.604330
https://doi.org/10.3109/03639045.2011.604330
Publikováno v:
Journal of Chemical & Engineering Data. 56:2909-2913
The solubility of urea in mixtures of acetonitrile (MeCN) and water was measured in terms of mole fraction over the entire range of MeCN/water compositions. With respect to mole fractions of the three components, it was found that in water-rich mixtu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e14586f2b56abfbb230509cf5878b314
https://doi.org/10.1021/je200122b
https://doi.org/10.1021/je200122b
Publikováno v:
Journal of Chromatographic Science. 49:57-62
In reversed-phase liquid chromatography (RP-LC), the retention of cationic analytes such as basic drugs is known to be enhanced by the presence of chaotropic additives in the mobile phase. In this study, the chaotropic effect of triflate anion was ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0a52823a4f2c89b825a6a9c7603fdff
https://doi.org/10.1093/chrsci/49.1.57
https://doi.org/10.1093/chrsci/49.1.57
Autor:
Patrick Drumm, Steven D. Fazio, Jyoti Patel, Hanumantha Rao Marrepalli, Loeser Eric M, Donald Drinkwater, Rudy Kircher
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 33:712-719
A method to form a UV-active derivative of 1-methyl-4-amino-piperazine (AMP) was developed. The method was based on the reaction of AMP with benzaldehyde, forming a stable derivative, which was UV-active. The method was used to analyze samples of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e52cc33bb5fa494f9c6bb1a6b9e42b3
https://doi.org/10.1080/10826071003608959
https://doi.org/10.1080/10826071003608959
Autor:
Stanislaw Babiak, Loeser Eric M
Publikováno v:
Chromatographia. 70:1311-1319
This study explored feasibility of utilizing sodium phosphate and mixtures of sodium phosphate and sodium perchlorate salts in mobile phases as UV transparent alternatives to the ammonium formate salts commonly used in LC–MS mobile phases. Chromato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ccf777bfca21aa806a3b1cef098dfbb
https://doi.org/10.1365/s10337-009-1326-2
https://doi.org/10.1365/s10337-009-1326-2
Publikováno v:
Journal of Chromatography A. 1216:3927-3932
A modified method for weighing HPLC columns filled with solvent is described. The method prevents the loss of traces of solvent from within the threads of the column. The method was tested by obtaining the weights of a C18 column filled with 10 diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80092882008a18f5eac315cae2af7baf
https://doi.org/10.1016/j.chroma.2009.03.003
https://doi.org/10.1016/j.chroma.2009.03.003
Autor:
Loeser Eric M
Publikováno v:
Chromatographia. 69:807-811
Formic acid is often used for pH adjustment in RP–LC mobile phases. However, under certain circumstances, formic acid can also behave as an organic co-solvent. This study illustrates two scenarios when the effects of formic acid as co-solvent will
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54f6f4150e574fb7dc4b83389a23e08e
https://doi.org/10.1365/s10337-009-1001-7
https://doi.org/10.1365/s10337-009-1001-7