Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Loes M. Butter"'
Autor:
Alessandra Tammaro, Eileen G. Daniels, Iman M. Hu, Kelly C. ‘t Hart, Kim Reid, Rio P. Juni, Loes M. Butter, Goutham Vasam, Rashmi Kamble, Aldo Jongejan, Richard I. Aviv, Joris J.T.H. Roelofs, Eleonora Aronica, Reinier A. Boon, Keir J. Menzies, Riekelt H. Houtkooper, Georges E. Janssens
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108681- (2024)
Summary: Aging increases the risk of age-related diseases, imposing substantial healthcare and personal costs. Targeting fundamental aging mechanisms pharmacologically can promote healthy aging and reduce this disease susceptibility. In this work, we
Externí odkaz:
https://doaj.org/article/42cc145abf8d478f88355c37c49e69d9
Autor:
Ye Liu, Lotte Kors, Loes M. Butter, Geurt Stokman, Nike Claessen, Coert J. Zuurbier, Stephen E. Girardin, Jaklien C. Leemans, Sandrine Florquin, Alessandra Tammaro
Publikováno v:
Cells, Vol 13, Iss 1, p 23 (2023)
Background: Chronic kidney disease often leads to kidney dysfunction due to renal fibrosis, regardless of the initial cause of kidney damage. Macrophages are crucial players in the progression of renal fibrosis as they stimulate inflammation, activat
Externí odkaz:
https://doaj.org/article/a19ace71ab7e4aec9b0f3be9ba50d498
Autor:
Melissa Uil, Angelique M. L. Scantlebery, Loes M. Butter, Per W. B. Larsen, Onno J. de Boer, Jaklien C. Leemans, Sandrine Florquin, Joris J. T. H. Roelofs
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Diabetic nephropathy (DN) is the leading cause of chronic kidney disease. Animal models are essential tools for designing new strategies to prevent DN. C57Bl/6 (B6) mice are widely used for transgenic mouse models, but are relatively resista
Externí odkaz:
https://doaj.org/article/ffb9045537bd4a1e9e4e57840a74a191
Autor:
Ingrid Stroo, Diba Emal, Loes M. Butter, Gwen J. Teske, Nike Claessen, Mark C. Dessing, Stephen E. Girardin, Sandrine Florquin, Jaklien C. Leemans
Publikováno v:
BMC Nephrology, Vol 19, Iss 1, Pp 1-8 (2018)
Abstract Background Chronic kidney disease (CKD) is characterized by sustained tissue damage and ongoing tubulo-interstitial inflammation and fibrosis. Pattern recognition receptors (PRRs) including Toll-like receptors (TLRs) and NOD-like receptors (
Externí odkaz:
https://doaj.org/article/8261a478aa0d4c7bbbf121c445108ca4
Autor:
Elena Rampanelli, Evelyn Orsó, Peter Ochodnicky, Gerhard Liebisch, Pieter J. Bakker, Nike Claessen, Loes M. Butter, Marius A. van den Bergh Weerman, Sandrine Florquin, Gerd Schmitz, Jaklien C. Leemans
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract The collateral effects of obesity/metabolic syndrome include inflammation and renal function decline. As renal disease in obesity can occur independently of hypertension and diabetes, other yet undefined causal pathological pathways must be
Externí odkaz:
https://doaj.org/article/2577425c3c0b44beacac710531476209
Autor:
Alessandra Tammaro, Angelique M. L. Scantlebery, Elena Rampanelli, Cristiana Borrelli, Nike Claessen, Loes M. Butter, Alessandra Soriani, Marco Colonna, Jaklien C. Leemans, Mark C. Dessing, Sandrine Florquin
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Long-term sequelae of acute kidney injury (AKI) are associated with incomplete recovery of renal function and the development of chronic kidney disease (CKD), which can be mediated by aberrant innate immune activation, mitochondrial pathology, and ac
Externí odkaz:
https://doaj.org/article/699c8e22845a458698ffddec0fd26569
Autor:
Ingrid Stroo, Loes M. Butter, Nike Claessen, Gwen J. Teske, Stephen J. Rubino, Stephen E. Girardin, Sandrine Florquin, Jaklien C. Leemans
Publikováno v:
Biology Open, Vol 1, Iss 12, Pp 1239-1247 (2012)
Summary It is indispensable to thoroughly characterize each animal model in order to distinguish between primary and secondary effects of genetic changes. The present study analyzed Nod1 and Nod2 double deficient (Nod1/2 DKO) mice under physiological
Externí odkaz:
https://doaj.org/article/2a097c4099aa4706965c17a2ba46174c
Autor:
Alessandra Tammaro, Lotte Kors, Jaklien C. Leemans, Gwendoline J. D. Teske, Sandrine Florquin, Loes M. Butter, James D. Mills, Gerd Schmitz, Elena Rampanelli, Gerhard Liebisch, Joris J. T. H. Roelofs, Angelique M. L. Scantlebery
Publikováno v:
The Journal of Pathology
Journal of pathology, 253(4), 404-414. John Wiley and Sons Ltd
Journal of pathology, 253(4), 404-414. John Wiley and Sons Ltd
Lipid accumulation is associated with various forms of acute renal injury; however, the causative factors and pathways underpinning this lipid accumulation have not been thoroughly investigated. In this study, we performed lipidomic profiling of rena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3cbc3e57117d8d362b0314db45ff57
https://doi.org/10.1002/path.5605
https://doi.org/10.1002/path.5605
Autor:
Per W. B. Larsen, Sandrine Florquin, Loes M. Butter, Joris J. T. H. Roelofs, Nike Claessen, Melissa Uil
Publikováno v:
FASEB journal, 34(10), 13750-13761. FASEB
Diabetic nephropathy (DN) is a major complication of diabetes and is associated with high risk for cardiovascular mortality, which is partially related to elevated platelet activity. Platelets are also active players in inflammation and fibrosis. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c08d4472377a6439c933a0e58cf5b0ed
https://doi.org/10.1096/fj.202000897r
https://doi.org/10.1096/fj.202000897r
Autor:
Alessandra Tammaro, Ingrid Stroo, Elena Rampanelli, Froilan Blank, Loes M Butter, Nike Claessen, Toshiyuki Takai, Marco Colonna, Jaklien C Leemans, Sandrine Florquin, Mark C Dessing
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82498 (2013)
Tubulo-interstitial damage is a common finding in the chronically diseased kidney and is characterized by ongoing inflammation and fibrosis leading to renal dysfunction and end-stage renal disease. Upon kidney injury, endogenous ligands can be releas
Externí odkaz:
https://doaj.org/article/b9002f040fe04bc5928bb616b3070021