Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Loes A. van de Pasch"'
Autor:
Lara Schawalder, Marc Kleiser, Michelle van Heck, Sanne Vendelbosch, Gideon Hönger, Stefan Schaub, Erik H. Rozemuller, Loes A. van de Pasch
Publikováno v:
Hla
Eplets are defined as distinct amino acid configurations on the surface of HLA molecules. The aim of this study was to estimate the immunogenicity of HLA-DQ eplets in a cohort of 221 pregnancies with HLA-DQ mismatches. We defined the immunogenicity o
Autor:
James Jones, Sanne Vendelbosch, Irene Hösli, Erik H. Rozemuller, Gideon Hönger, Matthias Niemann, Sarah Blümel, Loes A. van de Pasch, Lara Schawalder, Michelle van Heck, Stefan Schaub
Publikováno v:
HLA. 96:589-600
Eplets are functional units of structural epitopes on donor HLA, potentially recognized by complementarity-determining regions of the paratope of the recipients' B-cell receptors or antibodies (Ab). Their individual immunogenicity is poorly described
Publikováno v:
Human Immunology. 80:21
Publikováno v:
Human Immunology. 80:128
Autor:
Sanne Vendelbosch, Maarten T. Penning, Erik H. Rozemuller, Karin van Ham, Loes A. van de Pasch
Publikováno v:
Human Immunology. 79:42
Aim Killer-cell Immunoglobulin-like Receptors (KIRs) are encoded by 17 genes in the Leukocyte Receptor Complex (LRC). These genes are highly polymorphic, on the level of structural variants, and copy-number variation. These characteristics make it ch
Publikováno v:
Human Immunology. 79:139
Aim Accurate NGS-based HLA typing heavily depends on a reliable PCR amplification of HLA genes. Most protocols apply a method in which each HLA gene is amplified separately, after which amplicons are pooled and processed in a library preparation proc
Publikováno v:
Human Immunology. 79:138
Aim Accurate monitoring of the chimeric status after stem cell transplantation is essential for early detection of relapse and at the moment mainly performed by STR or qPCR. The major disadvantages of STR are the laborious data analysis and poor sens
Autor:
Stephen Buratowski, Dik van Leenen, TaeSoo Kim, Michael S. Kobor, Nathalie Brabers, Sebastiaan van Heesch, Frank C. P. Holstege, Joris J. Benschop, Thomas Hentrich, Cheuk W. Ko, Patrick Kemmeren, Sander R. van Hooff, Katrin Sameith, Julia M. Schulze, Philip Lijnzaad, Mariel O. Brok, Thanasis Margaritis, Marian J. A. Groot Koerkamp, Loes A.L. van de Pasch, Tineke L. Lenstra
Publikováno v:
Molecular Cell. 42:536-549
Packaging of DNA into chromatin has a profound impact on gene expression. To understand how changes in chromatin influence transcription, we analyzed 165 mutants of chromatin machinery components in Saccharomyces cerevisiae. mRNA expression patterns
Publikováno v:
Human Immunology. 78:78
Aim Accurate monitoring of the chimeric status of patients after stem cell transplantation is essential for early detection of transplant rejection or relapse. Currently, micro-chimerism levels are mostly assessed by Short Tandem Repeat (STR) fragmen
Centromere Binding and a Conserved Role in Chromosome Stability for SUMO-Dependent Ubiquitin Ligases
Autor:
Nathalie Brabers, Jimmy Ouellet, Antony J. Miles, Philip Lijnzaad, Yves Barral, Markus K. Brown, Geert J. P. L. Kops, Loes A.L. van de Pasch, Wilco Nijenhuis, Frank C. P. Holstege, Dik van Leenen
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65628 (2013)
PloS one
PLoS ONE
PLoS ONE, 8 (6)
PloS one
PLoS ONE
PLoS ONE, 8 (6)
The Saccharomyces cerevisiae Slx5/8 complex is the founding member of a recently defined class of SUMO-targeted ubiquitin ligases (STUbLs). Slx5/8 has been implicated in genome stability and transcription, but the precise contribution is unclear. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef416c65ce1c0bc9d73eadf6442513c1