Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Loes A Oosterhoff"'
Autor:
Talitha C. F. Spanjersberg, Loes A. Oosterhoff, Hedwig S. Kruitwagen, Noortje A. M. van den Dungen, Johannes C. M. Vernooij, Folkert W. Asselbergs, Michal Mokry, Bart Spee, Magdalena Harakalova, Frank G. van Steenbeek
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Vascular pathologies show locational predisposition throughout the body; further insights into the transcriptomics basis of this vascular heterogeneity are needed. We analyzed transcriptomes from cultured endothelial cells and vascular smoot
Externí odkaz:
https://doaj.org/article/084d9af137ee4c1b8e300e79be3a0038
Autor:
Maya W. Haaker, Hedwig S. Kruitwagen, Arie B. Vaandrager, Martin Houweling, Louis C. Penning, Martijn R. Molenaar, Monique E. vanWolferen, Loes A. Oosterhoff, Bart Spee, J. Bernd Helms
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 34, Iss 1, Pp 132-138 (2020)
Abstract Background Hepatic lipidosis is increasing in incidence in the Western world, with cats being particularly sensitive. When cats stop eating and start utilizing their fat reserves, free fatty acids (FFAs) increase in blood, causing an accumul
Externí odkaz:
https://doaj.org/article/9e1ab320d6b74ca9bb639a32d61656eb
Autor:
Hedwig S. Kruitwagen, Loes A. Oosterhoff, Ingrid G.W.H. Vernooij, Ingrid M. Schrall, Monique E. van Wolferen, Farah Bannink, Camille Roesch, Lisa van Uden, Martijn R. Molenaar, J. Bernd Helms, Guy C.M. Grinwis, Monique M.A. Verstegen, Luc J.W. van der Laan, Meritxell Huch, Niels Geijsen, Robert G. Vries, Hans Clevers, Jan Rothuizen, Baukje A. Schotanus, Louis C. Penning, Bart Spee
Publikováno v:
Stem Cell Reports, Vol 8, Iss 4, Pp 822-830 (2017)
Summary: Hepatic steatosis is a highly prevalent liver disease, yet research is hampered by the lack of tractable cellular and animal models. Steatosis also occurs in cats, where it can cause severe hepatic failure. Previous studies demonstrate the p
Externí odkaz:
https://doaj.org/article/1b75311bbf3843328b88a26d9590e37a
Autor:
Loes A. Oosterhoff, Hedwig S. Kruitwagen, Monique E. van Wolferen, Bas W.M. van Balkom, Michal Mokry, Nico Lansu, Noortje A.M. van den Dungen, Louis C. Penning, Talitha C.F. Spanjersberg, Johannes W. de Graaf, Tomas Veenendaal, Flin Zomerdijk, Joost O. Fledderus, Bart Spee, Frank G. van Steenbeek
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Vasculature performs a critical function in tissue homeostasis, supply of oxygen and nutrients, and the removal of metabolic waste products. Vascular problems are implicated in a large variety of pathologies and accurate in vitro models resembling na
Externí odkaz:
https://doaj.org/article/d3bcd76059fd4137b465861aad4ad624
Autor:
Hedwig S. Kruitwagen, Loes A. Oosterhoff, Monique E. van Wolferen, Chen Chen, Sathidpak Nantasanti Assawarachan, Kerstin Schneeberger, Anne Kummeling, Giora van Straten, Ies C. Akkerdaas, Christel R. Vinke, Frank G. van Steenbeek, Leonie W.L. van Bruggen, Jeannette Wolfswinkel, Guy C.M. Grinwis, Sabine A. Fuchs, Helmuth Gehart, Niels Geijsen, Robert G. Vries, Hans Clevers, Jan Rothuizen, Baukje A. Schotanus, Louis C. Penning, Bart Spee
Publikováno v:
Cells, Vol 9, Iss 2, p 410 (2020)
The shortage of liver organ donors is increasing and the need for viable alternatives is urgent. Liver cell (hepatocyte) transplantation may be a less invasive treatment compared with liver transplantation. Unfortunately, hepatocytes cannot be expand
Externí odkaz:
https://doaj.org/article/c674d01025924804a5b649c947eca488
Autor:
Sathidpak Nantasanti, Bart Spee, Hedwig S. Kruitwagen, Chen Chen, Niels Geijsen, Loes A. Oosterhoff, Monique E. van Wolferen, Nicolas Pelaez, Hille Fieten, Richard W. Wubbolts, Guy C. Grinwis, Jefferson Chan, Meritxell Huch, Robert R.G. Vries, Hans Clevers, Alain de Bruin, Jan Rothuizen, Louis C. Penning, Baukje A. Schotanus
Publikováno v:
Stem Cell Reports, Vol 5, Iss 5, Pp 895-907 (2015)
The recent development of 3D-liver stem cell cultures (hepatic organoids) opens up new avenues for gene and/or stem cell therapy to treat liver disease. To test safety and efficacy, a relevant large animal model is essential but not yet established.
Externí odkaz:
https://doaj.org/article/1abf448ce02c4f37b5e21cdc6b0ded40
Autor:
Xiaoyan Wu, Hsiaotzu Chien, Monique E. van Wolferen, Hedwig S. Kruitwagen, Loes A. Oosterhoff, Louis C. Penning
Publikováno v:
Veterinary Sciences, Vol 6, Iss 4, p 78 (2019)
Wilson’s disease (WD), an autosomal recessive disorder, results in copper accumulation in the liver as a consequence of mutations in the gene ATPase copper transporting beta (ATP7B). The disease is characterized by chronic hepatitis, eventually res
Externí odkaz:
https://doaj.org/article/c4b1737912334d57b76f0aa81e01a5be
Autor:
Ruby Lieshout, Chen Chen, Natalia Sánchez-Romero, Kerstin Schneeberger, Iris Pla Palacin, Louis C. Penning, Joery De Kock, Hans Clevers, Sabine A. Fuchs, Bart Spee, Monique E van Wolferen, Loes A Oosterhoff, Haaike Colemonts-Vroninks, Imre F. Schene, Ruurdtje Hoekstra, Pedro M. Baptista, Shicheng Ye, Luc J. W. van der Laan, Monique M A Verstegen, Gilles S van Tienderen, Frank G. van Steenbeek
Publikováno v:
Hepatology, 72(1), 257-270. John Wiley & Sons Ltd.
Zaguán: Repositorio Digital de la Universidad de Zaragoza
Universidad de Zaragoza
Hepatology (Baltimore, Md.)
Hepatology
Hepatology. American Association for the Study of Liver Diseases (AASLD)
Hepatology (Baltimore, Md.), 72(1), 257-270. John Wiley and Sons Ltd
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Zaguán: Repositorio Digital de la Universidad de Zaragoza
Universidad de Zaragoza
Hepatology (Baltimore, Md.)
Hepatology
Hepatology. American Association for the Study of Liver Diseases (AASLD)
Hepatology (Baltimore, Md.), 72(1), 257-270. John Wiley and Sons Ltd
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Background and Aims: The gap between patients on transplant waiting lists and available donor organs is steadily increasing. Human organoids derived from leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5)–positive adult stem cells r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fad3b8a1076fd1098e69342ff04b7e7
https://doi.org/10.1002/hep.31037
https://doi.org/10.1002/hep.31037
Autor:
Michal Mokry, Hedwig S. Kruitwagen, Frank G. van Steenbeek, Magdalena Harakalova, Noortje A.M. van den Dungen, Loes A Oosterhoff, Talitha C.F. Spanjersberg, Bart Spee
The locational predisposition of vascular pathologies illustrates the need for a better insight into vascular heterogeneity. To investigate the transcriptomic basis of angiodiversity, we isolated and analyzed transcriptomes from endothelial cells and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8a45852a7c305cc4a5804306c4fa10b
https://doi.org/10.1101/2021.10.20.465092
https://doi.org/10.1101/2021.10.20.465092
Autor:
Hedwig S, Kruitwagen, Loes A, Oosterhoff, Monique E, van Wolferen, Chen, Chen, Sathidpak, Nantasanti Assawarachan, Kerstin, Schneeberger, Anne, Kummeling, Giora, van Straten, Ies C, Akkerdaas, Christel R, Vinke, Frank G, van Steenbeek, Leonie W L, van Bruggen, Jeannette, Wolfswinkel, Guy C M, Grinwis, Sabine A, Fuchs, Helmuth, Gehart, Niels, Geijsen, Robert G, Vries, Hans, Clevers, Jan, Rothuizen, Baukje A, Schotanus, Louis C, Penning, Bart, Spee
Publikováno v:
Cells
The shortage of liver organ donors is increasing and the need for viable alternatives is urgent. Liver cell (hepatocyte) transplantation may be a less invasive treatment compared with liver transplantation. Unfortunately, hepatocytes cannot be expand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b6956646f14c62888d55af9dd83411cf
https://pubmed.ncbi.nlm.nih.gov/32053895
https://pubmed.ncbi.nlm.nih.gov/32053895